Mushrooms: A Wealth of Nutraceuticals and An Agent of Bioremediation informs readers about the growing role of mycotherapy and fungal biotechnology for a sustainable future. It presents reviews of efficient treatment strategies for different diseases with the help of mushrooms and derived nutraceuticals. This book also highlights efficient bioremediation strategies exhibited by common mushrooms.
Starting with topics on the nutritional and medicinal values of various edible and non-edible mushrooms, the contributors explore their bioactive components. The book progressively covers the antidiabetic, anticancer and antimcrobial potential of mushrooms. The contents are rounded up by reviews of the application of fungal xylanase enzymes and bioremediation of heavy metals from the environment. This is a comprehensive reference for researchers interested in working in the field of applied mycology for nutraceuticals and environmental bioremediation for pollution control.
Table of Contents
Chapter 1 Nutritional Composition of Mushroom
- Medicinal Attributes of Mushrooms
- Conclusion and Future Prospects
- Consent for Publication
- Conflict of Interest
- Acknowledgement
- References
Chapter 2 Mushrooms Against Malignancies: from Chemosensitization to Immunopotentiation
- Introduction
- Mushrooms as a Promising Source of Therapeutic Agents
- Anticancer Potential of Mushrooms
- Mushrooms in the Prevention of Malignancies
- Mushroom for Nutritional Management During/After Malignancies
- Mushrooms as Anti-Angiogenic Agents
- The Anti-Metastatic Potential of Mushroom
- Mushroom and Immuno-Potentiation Against Cancer
- Mushroom and Chemosensitization
- Anticancer Compounds of Mushrooms and Their Molecular Targets
- Future Prospective
- Conclusion
- Author Contributions
- Consent of Publication
- Conflict of Interest
- Acknowledgments
- References
Chapter 3 Anti-Proliferative, Anti-Angiogenic, Anti-Apoptotic, and Anti-Metastatic Effects of Mushroom
- Introduction
- Anti-Proliferative Effect
- Apoptosis
- Angiogenesis
- Immunomodulation
- Metastasis
- Conclusion
- Consent for Publication
- Conflict of Interest
- Acknowledgement
- References
Chapter 4 Antidiabetic Attributes of Mushrooms
- Sushil Kumar Dubey, Vinay Kumar Singh, Rahul Shyam and Mohan Prasad Singh
- Introduction
- Diabetes Mellitus (Dm)
- Diabetes Mellitus Type 1 (Dmt-1) or Insulin-Dependent Diabetes Mellitus (Iddm)
- Diabetes Mellitus Type 2 (Dmt-2) or Non-Insulin-Dependent Diabetes Mellitus (Niddm)
- Auricularia Auricula-Judae
- Agaricus Bisporus
- Cordycep Sinensis
- Ganoderma Lucidum
- Pleurotus Species
- Summary and Conclusion
- Future Perspective
- Consent for Publication
- Conflict of Interest
- Acknowledgement
- References
Chapter 5 Antimicrobial Potential of Mushrooms: Emergence of Mycotherapy
- Introduction
- Classification of Antimicrobial Agents
- Classification According to the Type of Action
- Classification Based on the Source of Antibacterial Agents
- Classification Based on Activity Spectrum
- Classification Based on Chemical Structure
- Β-Lactams
- Aminoglycosides
- Some Other Well-Known Antimicrobial Agents
- Tetracycline
- Macrolides
- Quinolone
- Streptogramin
- Function-Based Classification of Antibacterial Drugs
- Inhibitors of Membrane Function
- Protein Synthesis Inhibitor
- Nucleic Acid Aynthesis Inhibitor
- Mechanism of Antimicrobial Resistance
- Biomolecules of Mushrooms as a Natural Antimicrobial Agent: Mycotherapy
- Future Prospects and Conclusion
- Consent for Publication
- Conflict of Interest
- Acknowledgement
- References
Chapter 6 in Silico Interactions of the Biomolecules of Edible Mushrooms Against Lifestyle Diseases
- Introduction
- Biomolecules of Mushrooms
- Medicinal Properties of Mushroom
- Methods to Identify Interaction Among Biomolecules and Diseases
- Ligand Preparation
- Protein Preparation
- Determination of in Silico Pharmacokinetic, Physicochemical Parameters and Drug Likeliness of the Compound
- Molecular Docking
- Molecular Dynamic Simulation
- Conclusion
- Consent for Publication
- Conflict of Interest
- Acknowledgement
- References
Chapter 7 An Eco-Friendly Practice of Decontamination of Toxicants Using Fungi
- Introduction
- Role of Fungi in Mycoremediation
- Role of Fungal Enzymes Involved in Mycoremediation Techniques
- Cell-Bound Enzymes
- Mechanisms of Action of Fungi for Detoxification of Toxicants
- Bioremediation of Different Kinds of Toxicants
- Mycoremediation of Heavy Metals
- Mycoremediation of Chemicals [Pesticides and Herbicides]
- Mycoremediation of Pharmaceuticals
- Mycoremediation of Antibiotics
- Mycoremediation of Dyes
- Mycoremediation of Phthalates
- Efficiency of Macrofungi (Mushrooms) for Bioremediation of Toxicants
- Conclusion and Future Perspectives
- Consent for Publication
- Conflict of Interest
- Acknowledgement
- References
Chapter 8 Application of Mushroom in Bioremediation of Toxic Heavy Metal Ions
- Introduction
- Source of Heavy Metal Toxicities
- Substrate for Mushroom Cultivation
- Requirements for a Good Mushroom Substrate
- Commonly Used Substrates for Mushroom Cultivation
- Removal of Heavy Metals
- Methods for Removal of Heavy Metals
- Application of Mushroom in Bioremediation of Toxic Metal Ions
- Factors Affecting the Heavy Metal Removal
- Temperature
- pH
- Growth Medium or Substrate
- Conclusion
- Consent for Publication
- Conflict of Interest
- Acknowledgement
- References
Chapter 9 Mushrooms - a Promising Candidate for the Bio- Sorption of Heavy Metals from the Environment
- Introduction
- Biosorption
- Influence of Parameters on Biosorption
- Fungi - a Felicitous Biosorbent
- Mushroom/Macrofungi-Aided Biosorption of Heavy Metals
- Mechanism of Biosorption
- Conclusion
- Consent for Publication
- Conflict of Interest
- Acknowledgement
- References
Chapter 10 Application of Fungal Xylanases Enzymes
- Harit Jha and Ragini Arora
- Introduction
- Xylan
- Xylanases
- Sources of Xylanases
- Bacterial Xylanases
- Fungal Xylanases
- Catalytic Mechanism of Xylanase Action
- Applications of Fungal Xylanases
- Biofuel Industry
- Ethanol Production
- Xylanases in Animal Feed
- Bread, Food and Drinks Manufacture
- Pharmaceutical and Chemical Applications
- Textiles
- Paper and Cellulose Pulp
- Concluding Remarks
- Consent for Publication
- Conflict of Interest
- Acknowledgements
- References
- Subject Index
Author
- Mohan Prasad Singh
- Sachchida Nand Rai
