Synthesis and Applications of Isotopically-Labelled Compounds: Recent Advances and Emerging Topics reviews recent advances in the field of tritium, carbon-14, and stable isotope compound synthesis along with their analysis. The emerging field of the development of deuterated pharmaceuticals is also discussed, along with the application of isotopically labelled compounds in drug metabolism studies. There book presents a comprehensive guide to the field for the community, as well as newcomers, interested parties, or collaborators who need to be able to communicate with labeling groups. This book fills this gap and provides a "one-stop shop" by having a comprehensive review of recent developments. Sections cover analytical chemistry in depth and include new sections on methods of stable isotope analysis. Analytical chemistry aspects of these specific areas are also covered.
Table of Contents
1. General Introduction2. Recent advances in tritium chemistry
3. Recent advances in carbon-14 chemistry
4. Recent advances in the chemistry of PET and SPECT isotopes
5. Recent advances in the chemistry of stable isotopes
6. Preclinical and clinical studies of pharmaceuticals supported by labelled compounds
7. Non pharmaceutical applications of labelled compounds
8. Emerging new fields in the chemistry of isotopes and their application
9. Deuterated APIs
10. Recent advances in the analysis of isotopically labelled compounds
11. Radiolabeling of large molecules
12. Summary and outlook
