Fundamentals and Design of Drug Delivery Systems: A Textbook with Lab Activities is an essential resource for pharmaceutical sciences and engineering students. Covering all key concepts related to drug delivery courses, it introduces basic pharmacology, barriers to drug delivery, drug targeting, and novel drug delivery systems. Design considerations and approaches are thoroughly illustrated. The textbook reflects nanotechnology in various chapters and includes practical lab activities, providing a comprehensive understanding of drug delivery systems, experimental design, and data analysis. It is ideally suited for upper-undergraduate and graduate courses.
In addition to the foundational material, the textbook delves into cutting-edge topics such as biomimetic drug delivery systems, targeted delivery systems, stimuli-responsive systems, and micro/nano-robots-based drug delivery systems. Emerging fields like cell therapy, artificial intelligence (AI) in drug delivery, and 3D printing-based systems are also explored. Professionals in the Pharma industry will benefit from the innovative concepts and platforms presented, making it a valuable addition to their resources.
Table of Contents
1. Introduction2. Historical Aspects of Pharmacy and Delivery of Drugs
3. Basics of Pharmacology, Pharmacokinetics and Pharmacodynamics
4. Physiological and Biochemical Barriers to Drug Delivery
5. Prodrugs as Drug Delivery Systems
6. Engineered Carriers in Drug Delivery
7. Cell Encapsulation A Living Drug Delivery Approach
8. Diffusion-Controlled Drug Delivery Systems
9. Erodible Drug Delivery Systems
10. Osmotic-Controlled Drug Delivery Systems
11. Targeted Drug Delivery Systems
12. Biomimetic Drug Delivery Systems
13. Site-Specific Drug Delivery
14. Stimuli-Responsive Drug Delivery Systems
15. Other Drug Delivery Systems
16. Commercialization of Controlled Release Products
Authors
Wujie Zhang Professor of Chemical and Biomolecular Engineering at the Milwaukee School of Engineering (MSOE), USA.Dr. Wujie Zhang is a professor of Chemical and Biomolecular Engineering at the Milwaukee School of Engineering (MSOE). He received his Ph.D. degree in Biomedical Engineering from the University of South Carolina. Dr. Zhang's scholarly work and research span biomaterials, tissue engineering, drug delivery, and cancer treatment. Dr. Zhang's recent drug delivery-related research focuses on novel micro/nano-scale drug delivery systems design. Dr. Zhang has published more than 40 peer-reviewed journal articles in ACS Nano, Pharmaceutics, Pharmaceutical Development and Technology, and beyond. He recently authored the book Nanotechnology for Bioengineers. Dr. Zhang has taught the Engineering Controlled Drug Delivery course at MSOE for more than 10 years and developed numerous lab activities for the course. Dr. Zhang has been recognized by the ASEE's Prism magazine as one of 20 high-achieving researchers and educators under 40 (2018) and STEM Forward's Young Engineer of the Year (2022).