The global market for Long Read Sequencing was estimated at US$756.8 Million in 2024 and is projected to reach US$3.8 Billion by 2030, growing at a CAGR of 30.8% from 2024 to 2030. This comprehensive report provides an in-depth analysis of market trends, drivers, and forecasts, helping you make informed business decisions. The report includes the most recent global tariff developments and how they impact the Long Read Sequencing market.
Long read sequencing, also known as third-generation sequencing, refers to advanced DNA sequencing technologies capable of reading extended nucleotide sequences in a single pass - often exceeding tens of thousands of base pairs. Unlike short-read sequencing, which reads DNA fragments in small bits (typically 100-300 base pairs), long read sequencing provides a more complete and accurate picture of the genome by spanning repetitive and complex regions that short-read technologies cannot resolve effectively. This makes it especially valuable for de novo genome assembly, structural variant detection, epigenetic analysis, and studying previously uncharacterized genomic regions.
Technologies from providers like Pacific Biosciences (PacBio) and Oxford Nanopore Technologies (ONT) are at the forefront of this field, offering highly scalable and increasingly cost-effective solutions for long read analysis. These platforms are transforming genomics research and clinical diagnostics by enabling comprehensive insights into human diseases, microbial communities, plant genomics, and cancer genomics. Their ability to capture full-length transcripts and methylation patterns also enhances functional genomics and transcriptome profiling. As the demand for more precise and complete genetic data grows, long read sequencing is playing an increasingly central role in modern molecular biology.
What Innovations and Use Cases Are Accelerating the Adoption of Long Read Sequencing?
The evolution of long read sequencing is being shaped by continuous advancements in read accuracy, throughput, and portability. Recent iterations of PacBio`s HiFi reads and Oxford Nanopore’s Q20+ chemistry have significantly improved the base-calling accuracy of long reads, making them competitive with short-read platforms in both precision and reliability. These innovations have expanded long read sequencing’s applicability across clinical diagnostics, personalized medicine, and rare disease identification, where accurate detection of structural variants, gene fusions, and large insertions or deletions is critical.
Long read technologies are also being increasingly used in microbiome analysis and metagenomics, where the ability to fully resolve microbial genomes from complex samples enhances the understanding of microbial diversity, antibiotic resistance, and pathogen surveillance. In oncology, long reads are aiding in the detection of tumor heterogeneity and somatic structural variations that inform treatment decisions. The portability of platforms like ONT’s MinION device is enabling in-field and point-of-care sequencing for infectious disease tracking, environmental genomics, and food safety testing. Furthermore, long read sequencing is being integrated into hybrid sequencing strategies - combining long and short reads - to balance cost, accuracy, and depth of coverage, particularly in population-scale genome projects.
What Factors Are Fueling the Expansion of the Long Read Sequencing Market?
The growth in the global long read sequencing market is driven by several factors, including increasing demand for comprehensive genomic insights, declining sequencing costs, and expanding applications in clinical and agricultural genomics. As researchers and clinicians seek to decode complex genetic regions and structural variations that short-read sequencing often misses, long read platforms are being increasingly adopted for more accurate and complete genomic profiling. This demand is particularly pronounced in oncology, rare disease diagnostics, neurogenetics, and prenatal screening, where genomic complexity requires high-resolution analysis.
In addition, the rising prevalence of personalized and precision medicine is catalyzing the need for technologies that can deliver actionable insights from individual genomic data. Government-backed genomic initiatives, such as national population sequencing projects and rare disease registries, are also contributing to market growth by incorporating long read platforms to ensure data completeness and utility. Moreover, growing investments in agricultural biotechnology and plant genomics are expanding the use of long reads in crop trait analysis, genome editing validation, and biodiversity studies. The continuous innovation in sequencing chemistry, device miniaturization, and cloud-based bioinformatics is lowering the entry barrier for new users, further accelerating market adoption across academic, clinical, and commercial domains.
Segments: Product (Instruments, Consumables, Services); Technology (Single Molecule Real Time Sequencing, Nanopore Sequencing, Others); Workflow (Pre-sequencing, Sequencing, Data Analysis); Application (Whole Genome Sequencing, Targeted Sequencing, Metagenomics, RNA Sequencing, Epigenetics, Others); End-Use (Academic & Research Institutes, Hospitals & Clinics, Pharma & Biotech Companies, Others)
Geographic Regions/Countries: World; United States; Canada; Japan; China; Europe (France; Germany; Italy; United Kingdom; Spain; Russia; and Rest of Europe); Asia-Pacific (Australia; India; South Korea; and Rest of Asia-Pacific); Latin America (Argentina; Brazil; Mexico; and Rest of Latin America); Middle East (Iran; Israel; Saudi Arabia; United Arab Emirates; and Rest of Middle East); and Africa.
The analysts continuously track trade developments worldwide, drawing insights from leading global economists and over 200 industry and policy institutions, including think tanks, trade organizations, and national economic advisory bodies. This intelligence is integrated into forecasting models to provide timely, data-driven analysis of emerging risks and opportunities.
Global Long Read Sequencing Market - Key Trends & Drivers Summarized
What Is Long Read Sequencing and Why Is It Revolutionizing Genomics?Long read sequencing, also known as third-generation sequencing, refers to advanced DNA sequencing technologies capable of reading extended nucleotide sequences in a single pass - often exceeding tens of thousands of base pairs. Unlike short-read sequencing, which reads DNA fragments in small bits (typically 100-300 base pairs), long read sequencing provides a more complete and accurate picture of the genome by spanning repetitive and complex regions that short-read technologies cannot resolve effectively. This makes it especially valuable for de novo genome assembly, structural variant detection, epigenetic analysis, and studying previously uncharacterized genomic regions.
Technologies from providers like Pacific Biosciences (PacBio) and Oxford Nanopore Technologies (ONT) are at the forefront of this field, offering highly scalable and increasingly cost-effective solutions for long read analysis. These platforms are transforming genomics research and clinical diagnostics by enabling comprehensive insights into human diseases, microbial communities, plant genomics, and cancer genomics. Their ability to capture full-length transcripts and methylation patterns also enhances functional genomics and transcriptome profiling. As the demand for more precise and complete genetic data grows, long read sequencing is playing an increasingly central role in modern molecular biology.
What Innovations and Use Cases Are Accelerating the Adoption of Long Read Sequencing?
The evolution of long read sequencing is being shaped by continuous advancements in read accuracy, throughput, and portability. Recent iterations of PacBio`s HiFi reads and Oxford Nanopore’s Q20+ chemistry have significantly improved the base-calling accuracy of long reads, making them competitive with short-read platforms in both precision and reliability. These innovations have expanded long read sequencing’s applicability across clinical diagnostics, personalized medicine, and rare disease identification, where accurate detection of structural variants, gene fusions, and large insertions or deletions is critical.
Long read technologies are also being increasingly used in microbiome analysis and metagenomics, where the ability to fully resolve microbial genomes from complex samples enhances the understanding of microbial diversity, antibiotic resistance, and pathogen surveillance. In oncology, long reads are aiding in the detection of tumor heterogeneity and somatic structural variations that inform treatment decisions. The portability of platforms like ONT’s MinION device is enabling in-field and point-of-care sequencing for infectious disease tracking, environmental genomics, and food safety testing. Furthermore, long read sequencing is being integrated into hybrid sequencing strategies - combining long and short reads - to balance cost, accuracy, and depth of coverage, particularly in population-scale genome projects.
What Factors Are Fueling the Expansion of the Long Read Sequencing Market?
The growth in the global long read sequencing market is driven by several factors, including increasing demand for comprehensive genomic insights, declining sequencing costs, and expanding applications in clinical and agricultural genomics. As researchers and clinicians seek to decode complex genetic regions and structural variations that short-read sequencing often misses, long read platforms are being increasingly adopted for more accurate and complete genomic profiling. This demand is particularly pronounced in oncology, rare disease diagnostics, neurogenetics, and prenatal screening, where genomic complexity requires high-resolution analysis.
In addition, the rising prevalence of personalized and precision medicine is catalyzing the need for technologies that can deliver actionable insights from individual genomic data. Government-backed genomic initiatives, such as national population sequencing projects and rare disease registries, are also contributing to market growth by incorporating long read platforms to ensure data completeness and utility. Moreover, growing investments in agricultural biotechnology and plant genomics are expanding the use of long reads in crop trait analysis, genome editing validation, and biodiversity studies. The continuous innovation in sequencing chemistry, device miniaturization, and cloud-based bioinformatics is lowering the entry barrier for new users, further accelerating market adoption across academic, clinical, and commercial domains.
Report Scope
The report analyzes the Long Read Sequencing market, presented in terms of market value (US$ Thousand). The analysis covers the key segments and geographic regions outlined below.Segments: Product (Instruments, Consumables, Services); Technology (Single Molecule Real Time Sequencing, Nanopore Sequencing, Others); Workflow (Pre-sequencing, Sequencing, Data Analysis); Application (Whole Genome Sequencing, Targeted Sequencing, Metagenomics, RNA Sequencing, Epigenetics, Others); End-Use (Academic & Research Institutes, Hospitals & Clinics, Pharma & Biotech Companies, Others)
Geographic Regions/Countries: World; United States; Canada; Japan; China; Europe (France; Germany; Italy; United Kingdom; Spain; Russia; and Rest of Europe); Asia-Pacific (Australia; India; South Korea; and Rest of Asia-Pacific); Latin America (Argentina; Brazil; Mexico; and Rest of Latin America); Middle East (Iran; Israel; Saudi Arabia; United Arab Emirates; and Rest of Middle East); and Africa.
Key Insights:
- Market Growth: Understand the significant growth trajectory of the Instruments segment, which is expected to reach US$2.6 Billion by 2030 with a CAGR of a 32.5%. The Consumables segment is also set to grow at 28.3% CAGR over the analysis period.
- Regional Analysis: Gain insights into the U.S. market, estimated at $206.2 Million in 2024, and China, forecasted to grow at an impressive 40.4% CAGR to reach $973.2 Million by 2030. Discover growth trends in other key regions, including Japan, Canada, Germany, and the Asia-Pacific.
Why You Should Buy This Report:
- Detailed Market Analysis: Access a thorough analysis of the Global Long Read Sequencing Market, covering all major geographic regions and market segments.
- Competitive Insights: Get an overview of the competitive landscape, including the market presence of major players across different geographies.
- Future Trends and Drivers: Understand the key trends and drivers shaping the future of the Global Long Read Sequencing Market.
- Actionable Insights: Benefit from actionable insights that can help you identify new revenue opportunities and make strategic business decisions.
Key Questions Answered:
- How is the Global Long Read Sequencing Market expected to evolve by 2030?
- What are the main drivers and restraints affecting the market?
- Which market segments will grow the most over the forecast period?
- How will market shares for different regions and segments change by 2030?
- Who are the leading players in the market, and what are their prospects?
Report Features:
- Comprehensive Market Data: Independent analysis of annual sales and market forecasts in US$ Million from 2024 to 2030.
- In-Depth Regional Analysis: Detailed insights into key markets, including the U.S., China, Japan, Canada, Europe, Asia-Pacific, Latin America, Middle East, and Africa.
- Company Profiles: Coverage of players such as 10x Genomics, Agilent Technologies, BGI Genomics, Bionano Genomics, CD Genomics and more.
- Complimentary Updates: Receive free report updates for one year to keep you informed of the latest market developments.
Select Competitors (Total 42 Featured):
- 10x Genomics
- Agilent Technologies
- BGI Genomics
- Bionano Genomics
- CD Genomics
- Element Biosciences
- FG Technologies
- GENEWIZ (Azenta Life Sciences)
- Illumina, Inc.
- MGI Tech Co., Ltd.
- MicrobesNG
- Oxford Nanopore Technologies
- Pacific Biosciences (PacBio)
- Qiagen
- Quantapore, Inc.
- Singular Genomics
- Stratos Genomics
- Thermo Fisher Scientific
- Ultima Genomics
- Universal Sequencing Technology Corp.
Tariff Impact Analysis: Key Insights for 2025
Global tariff negotiations across 180+ countries are reshaping supply chains, costs, and competitiveness. This report reflects the latest developments as of April 2025 and incorporates forward-looking insights into the market outlook.The analysts continuously track trade developments worldwide, drawing insights from leading global economists and over 200 industry and policy institutions, including think tanks, trade organizations, and national economic advisory bodies. This intelligence is integrated into forecasting models to provide timely, data-driven analysis of emerging risks and opportunities.
What’s Included in This Edition:
- Tariff-adjusted market forecasts by region and segment
- Analysis of cost and supply chain implications by sourcing and trade exposure
- Strategic insights into geographic shifts
Buyers receive a free July 2025 update with:
- Finalized tariff impacts and new trade agreement effects
- Updated projections reflecting global sourcing and cost shifts
- Expanded country-specific coverage across the industry
Table of Contents
I. METHODOLOGYII. EXECUTIVE SUMMARY2. FOCUS ON SELECT PLAYERSIV. COMPETITION
1. MARKET OVERVIEW
3. MARKET TRENDS & DRIVERS
4. GLOBAL MARKET PERSPECTIVE
III. MARKET ANALYSIS
Companies Mentioned (Partial List)
A selection of companies mentioned in this report includes, but is not limited to:
- 10x Genomics
- Agilent Technologies
- BGI Genomics
- Bionano Genomics
- CD Genomics
- Element Biosciences
- FG Technologies
- GENEWIZ (Azenta Life Sciences)
- Illumina, Inc.
- MGI Tech Co., Ltd.
- MicrobesNG
- Oxford Nanopore Technologies
- Pacific Biosciences (PacBio)
- Qiagen
- Quantapore, Inc.
- Singular Genomics
- Stratos Genomics
- Thermo Fisher Scientific
- Ultima Genomics
- Universal Sequencing Technology Corp.
Table Information
| Report Attribute | Details |
|---|---|
| No. of Pages | 85 |
| Published | April 2025 |
| Forecast Period | 2024 - 2030 |
| Estimated Market Value ( USD | $ 756.8 Million |
| Forecasted Market Value ( USD | $ 3800 Million |
| Compound Annual Growth Rate | 30.8% |
| Regions Covered | Global |
