Biomanufacturing - Global Strategic Business Report

The global market for Biomanufacturing was estimated at US$21.5 Billion in 2024 and is projected to reach US$31.5 Billion by 2030, growing at a CAGR of 6.6% from 2024 to 2030. This comprehensive report provides an in-depth analysis of market trends, drivers, and forecasts, helping you make informed business decisions. The report includes the most recent global tariff developments and how they impact the Biomanufacturing market.

Global Biomanufacturing Market - Key Trends & Drivers Summarized

Why Is Biomanufacturing Reshaping the Global Landscape of Pharmaceutical and Industrial Production?

Biomanufacturing is revolutionizing modern production processes by using living organisms, cells, or biological systems to develop a broad spectrum of products including pharmaceuticals, biofuels, industrial enzymes, food ingredients, and biomaterials. Unlike traditional chemical manufacturing that often relies on high temperatures, toxic solvents, and fossil-derived inputs, biomanufacturing leverages biologically-based and often renewable methods to produce complex molecules with high specificity and efficiency. In the pharmaceutical sector, biomanufacturing plays a central role in the production of biologics, including monoclonal antibodies, vaccines, hormones like insulin, and gene or cell therapies. These therapies often require precise protein structures and post-translational modifications that only living cells can provide. The value of biomanufacturing extends beyond healthcare it is also transforming the agricultural, energy, and textile sectors through sustainable alternatives like microbial fermentation for fertilizers, algae-based biofuels, and biodegradable biopolymers. As global industries aim to lower carbon footprints and reduce environmental impact, biomanufacturing offers a cleaner, safer, and more sustainable alternative that aligns with ESG goals and circular economy models. Its ability to produce high-value, low-volume products with minimal waste and energy consumption is especially relevant in an era of increasing resource scarcity and climate consciousness. Biomanufacturing isn’t just an upgrade to traditional production it represents a fundamental shift in how we conceptualize, design, and scale the manufacturing of the future.

How Are Technological Advancements Powering the Next Generation of Biomanufacturing?

Technological innovations are significantly expanding the potential, precision, and productivity of biomanufacturing processes. Central to this advancement is synthetic biology, which enables scientists to engineer microorganisms like yeast, bacteria, or mammalian cells with custom-designed genetic blueprints that optimize metabolic pathways for higher yield and target specificity. CRISPR and other gene-editing tools allow for rapid, precise modifications that were previously labor-intensive and unpredictable. Meanwhile, advances in bioprocessing technologies such as single-use bioreactors, continuous manufacturing, and perfusion systems are increasing scalability and reducing production costs. Digitalization is also transforming biomanufacturing smart factories equipped with real-time sensors, data analytics, and AI algorithms enable predictive maintenance, process optimization, and quality assurance at unprecedented levels. Automation through robotics and digital twins allows for high-throughput experimentation and accelerated product development cycles. Innovations in cell culture media, feed strategies, and upstream/downstream integration have improved process yields and consistency across batches. Furthermore, machine learning is being used to simulate fermentation outcomes, optimize protein folding, and reduce time to market. Cloud-based platforms now support collaborative development, enabling stakeholders from academia, biotech startups, and big pharma to share data and refine processes in real time. These technologies collectively push biomanufacturing beyond laboratory confines into scalable, efficient, and industrial-grade operations that can adapt to evolving demand and therapeutic complexity. As innovation continues to converge across biology, computing, and engineering, biomanufacturing is positioned to deliver faster, cheaper, and more customizable production solutions on a global scale.

Which Sectors and Global Markets Are Leading the Adoption and Expansion of Biomanufacturing?

The adoption of biomanufacturing is accelerating across a diverse array of industries and global regions, each leveraging its capabilities to address specific economic, healthcare, and environmental needs. In the pharmaceutical and biotechnology sectors, leading companies in the United States and Europe are heavily investing in biomanufacturing to meet the growing demand for biologics and personalized medicine. With blockbuster biologics accounting for a significant portion of pharmaceutical revenues, companies like Genentech, Amgen, and Roche are expanding their biomanufacturing footprints both in-house and through contract development and manufacturing organizations (CDMOs). In Asia-Pacific, countries like China, India, South Korea, and Singapore are rapidly scaling up biomanufacturing capabilities, supported by government incentives, skilled labor, and expanding healthcare markets. China, for instance, is making biomanufacturing a strategic priority under its 'Made in China 2025' initiative. The food and agriculture sectors are adopting biomanufacturing to produce alternative proteins, enzymes, and bio-based preservatives, catering to a growing global demand for plant-based and sustainable diets. Environmental and energy sectors are leveraging microbial and algae-based systems to generate biofuels and biodegradable plastics, especially in regions where green technology investment is high. Latin America is beginning to emerge as a key player in agricultural biomanufacturing, thanks to its vast biomass availability and biodiversity. In all these regions, biomanufacturing is being integrated into broader national strategies focused on bioeconomy development, innovation ecosystems, and industrial decarbonization. This multi-sectoral and global push is transforming biomanufacturing into a foundational industry with far-reaching economic and environmental impact.

What Is Fueling the Growth in the Global Biomanufacturing Market?

The growth in the global biomanufacturing market is driven by several interconnected factors related to healthcare demand, environmental urgency, technological maturity, and supportive policy frameworks. One of the most prominent drivers is the exponential rise in demand for biologics, including complex therapeutics like monoclonal antibodies, gene therapies, and mRNA vaccines. This demand is further amplified by the global aging population and the increasing incidence of chronic diseases that require long-term, biologically-targeted treatment solutions. The COVID-19 pandemic demonstrated the strategic importance of resilient and scalable biomanufacturing capacity, leading to massive investments in both public and private infrastructure. Environmental sustainability goals are also driving adoption, as industries seek alternatives to petrochemical-based manufacturing. Biomanufacturing offers a low-emission, waste-minimizing pathway that aligns with net-zero targets and circular economy models. On the regulatory front, faster approval pathways for biologics and biosimilars, along with government grants and tax incentives, are lowering barriers to entry for startups and accelerating innovation. Advances in automation, process control, and modular facility design are reducing time-to-market and enabling flexible production capable of meeting both large-scale and niche demands. Additionally, increasing collaboration between academia, biotech companies, and multinational manufacturers is creating innovation clusters and accelerating the development of next-generation platforms. As more industries and governments recognize the strategic value of biological manufacturing, investment and innovation in this field are set to continue rising. The result is a dynamic, expanding market with the potential to redefine global production norms where biology becomes the engine of industry.

Key Insights:

• Market Growth: Understand the significant growth trajectory of the Continuous Upstream Biomanufacturing segment, which is expected to reach US$19.0 Billion by 2030 with a CAGR of a 7.9%. The Single-Use Upstream Biomanufacturing segment is also set to grow at 4.6% CAGR over the analysis period.
• Regional Analysis: Gain insights into the U.S. market, valued at $5.9 Billion in 2024, and China, forecasted to grow at an impressive 10.6% CAGR to reach $6.6 Billion by 2030. Discover growth trends in other key regions, including Japan, Canada, Germany, and the Asia-Pacific.

Why You Should Buy This Report:

• Detailed Market Analysis: Access a thorough analysis of the Global Biomanufacturing Market, covering all major geographic regions and market segments.
• Competitive Insights: Get an overview of the competitive landscape, including the market presence of major players across different geographies.
• Future Trends and Drivers: Understand the key trends and drivers shaping the future of the Global Biomanufacturing Market.
• Actionable Insights: Benefit from actionable insights that can help you identify new revenue opportunities and make strategic business decisions.

Key Questions Answered:

• How is the Global Biomanufacturing Market expected to evolve by 2030?
• What are the main drivers and restraints affecting the market?
• Which market segments will grow the most over the forecast period?
• How will market shares for different regions and segments change by 2030?
• Who are the leading players in the market, and what are their prospects?

Report Features:

• Comprehensive Market Data: Independent analysis of annual sales and market forecasts in US$ Million from 2024 to 2030.
• In-Depth Regional Analysis: Detailed insights into key markets, including the U.S., China, Japan, Canada, Europe, Asia-Pacific, Latin America, Middle East, and Africa.
• Company Profiles: Coverage of players such as AbbVie Inc., Amgen Inc., Biocon Limited, BioNTech SE, and more.
• Complimentary Updates: Receive free report updates for one year to keep you informed of the latest market developments.

Some of the 36 companies featured in this Biomanufacturing market report include:

• AbbVie Inc.
• Amgen Inc.
• Biocon Limited
• BioNTech SE
• Boehringer Ingelheim GmbH
• Bristol-Myers Squibb Company
• Catalent, Inc.
• Cytiva
• Eli Lilly and Company
• FUJIFILM Diosynth Biotechnologies
• Genentech, Inc.
• Ginkgo Bioworks Holdings, Inc.
• Lonza Group AG
• Moderna, Inc.
• Novartis AG
• Pfizer Inc.
• Regeneron Pharmaceuticals, Inc.
• Roche Holding AG
• Samsung Biologics Co., Ltd.
• WuXi Biologics

This edition integrates the latest global trade and economic shifts as of June 2025 into comprehensive market analysis. Key updates include:

• Tariff and Trade Impact: Insights into global tariff negotiations across 180+ countries, with analysis of supply chain turbulence, sourcing disruptions, and geographic realignment. Special focus on 2025 as a pivotal year for trade tensions, including updated perspectives on the Trump-era tariffs.
• Adjusted Forecasts and Analytics: Revised global and regional market forecasts through 2030, incorporating tariff effects, economic uncertainty, and structural changes in globalization. Includes segmentation by product, technology, type, material, distribution channel, application, and end-use, with historical analysis since 2015.
• Strategic Market Dynamics: Evaluation of revised market prospects, regional outlooks, and key economic indicators such as population and urbanization trends.
• Innovation & Technology Trends: Latest developments in product and process innovation, emerging technologies, and key industry drivers shaping the competitive landscape.
• Competitive Intelligence: Updated global market share estimates for 2025, competitive positioning of major players (Strong/Active/Niche/Trivial), and refined focus on leading global brands and core players.
• Expert Insight & Commentary: Strategic analysis from economists, trade experts, and domain specialists to contextualize market shifts and identify emerging opportunities.
• Complimentary Update: Buyers receive a free July 2025 update with finalized tariff impacts, new trade agreement effects, revised projections, and expanded country-level coverage.