Ichthyosis Epidemiology Forecast 2025-2034

The ichthyosis epidemiology forecast suggests that the prevalence of the condition is likely to vary across different populations, influenced by genetic factors, healthcare access, and diagnostic improvements. Ichthyosis vulgaris has an incidence of 1 in 300 people. Epidermolytic hyperkeratosis occurs in 1 in 300,000 individuals, whereas X-linked recessive ichthyosis affects 1 in 6,000 males. Further, ichthyosis is estimated to affect 5 to 10 per 100,000 people worldwide, as per Maritska, Ziske, et al. (2024).

Ichthyosis Epidemiology Forecast Report Coverage

The “Ichthyosis Epidemiology Forecast Report 2025-2034” offers comprehensive information on the prevalence and demographics of ichthyosis. It projects the future incidence and prevalence rates of ichthyosis cases across various populations. The study covers age, gender, and type as major determinants of the ichthyosis population. The report highlights patterns in the prevalence of ichthyosis over time and projects future trends based on multiple variables.

The report provides a comprehensive overview of the disease, as well as historical and projected data on ichthyosis epidemiology in the 8 major markets.

Regions Covered

• The United States
• Germany
• France
• Italy
• Spain
• The United Kingdom
• Japan
• India

Ichthyosis Understanding: Disease Overview

Ichthyosis refers to a group of genetic skin disorders characterized by the abnormal accumulation of dead skin cells, leading to dry, thick, and scaly skin. The condition occurs due to a defect in the skin’s ability to shed its outermost layer of cells.

The severity of symptoms can vary depending on the type of ichthyosis. Ichthyosis vulgaris is the most common form, causing dry, scaly patches primarily on the arms, legs, and torso. On the other hand, lamellar ichthyosis is a more severe form of ichthyosis, characterized by large, dark, plate-like scales. Harlequin Ichthyosis is considered the most severe type of ichthyosis, causing thick, hard plates of skin to cover the body. It is typically seen at birth and can lead to life-threatening complications.

Ichthyosis Epidemiology Perspective

The ichthyosis epidemiology division offers information on the patient pool from history to the present as well as the projected trend for each of the 8 major markets. The publisher provides both current and predicted trends for ichthyosis epidemiology scenario by examining a wide range of studies. Additionally, the report covers the diagnosed patient pool for ichthyosis and their trends. The ichthyosis detailed epidemiology segmentation is broken down into specific categories, such as total prevalent cases in males and females, and total diagnosed cases across different age groups and patient pools.

• Ichthyosis is estimated to affect 5 to 10 per 100,000 people worldwide, with lamellar ichthyosis being a significant form of autosomal recessive congenital ichthyosis, as per Maritska, Ziske, et al. (2024). Additionally, lamellar ichthyosis is recognized as a major type of inherited ichthyosis that usually presents in a nonsyndromic form.
• Ichthyosis vulgaris is the most common type of ichthyosis, inherited in an autosomal dominant pattern, with an incidence of 1 in 300 people. Epidermolytic hyperkeratosis, which also follows an autosomal dominant pattern, occurs in 1 in 300,000 people. Lamellar ichthyosis, a more severe form, is an autosomal recessive disorder, with an incidence of 1 in 300,000. X-linked recessive ichthyosis affects 1 in 6,000 males.
• In the United Kingdom, a study of 6,501 healthy school children found the incidence of ichthyosis vulgaris to be 1 in 250. Another large epidemiological study reported the incidence of X-linked recessive ichthyosis as 1 in 6,190 males.

Age-Based Ichthyosis Epidemiology Insights

Ichthyosis vulgaris follows an autosomal semi-dominant inheritance pattern, with a milder form of the condition seen in heterozygotes. The condition typically presents in infancy, and most patients show noticeable clinical signs by the age of 5. The symptoms often start with dry, scaly skin, which becomes more apparent as the child grows.

Gender-Based Ichthyosis Epidemiology Insights

X-linked ichthyosis is a genetic skin disorder that affects individuals across all ethnic groups and races worldwide, but it is much more common in males than females, due to its inheritance pattern. It is the second most common type of ichthyosis, after ichthyosis vulgaris, with an incidence of 1 in 2,500 to 1 in 6,000 males.

Country-wise Ichthyosis Epidemiology Segment

The ichthyosis epidemiology data and findings from the United States, Germany, Spain, Italy, France, the United Kingdom, Japan, and India are also provided in the epidemiology section.

The epidemiology of ichthyosis varies between countries, owing to differences in factors such as genetic predispositions, healthcare access, environmental conditions, and diagnostic practices. Genetic variations within different populations can significantly impact the prevalence rates of specific types of ichthyosis. In the United Kingdom, the frequency of Harlequin ichthyosis is estimated to be about 5 cases per year, according to the British Skin Foundation.

Ichthyosis: Treatment Overview

The primary treatment for ichthyosis involves using moisturizers, such as thick creams, lotions, or oils, to keep the skin hydrated and prevent dryness. Exfoliating creams with ingredients like urea, salicylic acid, or alpha-hydroxy acids are commonly used to reduce scaling.

Ichthyosis therapeutics, such as topical retinoids, are prescribed to accelerate skin cell turnover and prevent the skin from becoming too thick. Oral retinoids, such as acitretin, are used in severe ichthyosis cases to normalize skin cell growth. To prevent infections, antibiotics or antifungal treatments are recommended if the skin becomes cracked or irritated.

Key Questions Answered

• What are the key findings of ichthyosis epidemiology in the 8 major markets?
• What will be the total number of patients with ichthyosis across the 8 major markets during the forecast period?
• What was the country-wise ichthyosis epidemiology scenario in the 8 major markets in the historical period?
• Which country will have the highest number of ichthyosis patients during the forecast period of 2025-2034?
• Which key factors would influence the shift in the patient population of ichthyosis during the forecast period of 2025-2034?
• What are the currently available treatments in the ichthyosis market?
• What are the disease risks, signs, symptoms, and unmet needs of ichthyosis?

Scope of the Ichthyosis Epidemiology Report

• The report covers a detailed analysis of signs and symptoms, causes, risk factors, pathophysiology, diagnosis, treatment options, and classification/types of ichthyosis based on several factors.
• Ichthyosis Epidemiology Forecast Report covers data for the eight major markets (the US, France, Germany, Italy, Spain, the UK, Japan, and India).
• The ichthyosis report helps to identify the patient population and the unmet needs are highlighted along with an assessment of the disease's risk and burden.

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