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T-Type Calcium Channel Antagonists Pipeline Analysis Report 2025

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    Report

  • 200 Pages
  • June 2025
  • Region: Global
  • Expert Market Research
  • ID: 6102655
The T-type calcium channel antagonists drug pipeline is gaining significant attention due to their potential in treating various diseases, including epilepsy, chronic pain, and cardiovascular disorders. These drugs work by selectively blocking T-type calcium channels, which play a crucial role in the pathophysiology of these conditions. With growing research efforts, the pipeline is poised for growth, driven by advancements in drug formulation and targeted therapies. The increasing prevalence of neurological and cardiovascular diseases, along with a greater focus on precision medicine, is expected to propel the development and approval of T-type calcium channel antagonists in the coming years, offering new treatment avenues.

Report Coverage

The T-type Calcium Channel Antagonists Drug Pipeline Insight Report by the publisher gives comprehensive insights into T-type calcium channel antagonists therapeutics currently undergoing clinical trials. It covers various aspects related to the details of each of these drugs under development for T-type calcium channel antagonists. The T-type calcium channel antagonists report assessment includes the analysis of over 100 pipeline drugs and 50+ companies. The T-type calcium channel antagonists pipeline landscape will include an analysis based on efficacy and safety measure outcomes published for the trials, including their adverse effects on patients suffering from the condition and alignment with T-type calcium channel antagonists treatment guidelines to ensure optimal care practices.

The assessment part will include a detailed analysis of each drug, drug class, clinical studies, phase type, drug type, route of administration, and ongoing product development activities related to T-type calcium channel antagonists.

T-Type Calcium Channel Antagonists Drug Pipeline Outlook

T-type calcium channel antagonists inhibit the influx of calcium ions through T-type calcium channels, which are crucial for regulating neuronal excitability and smooth muscle contraction. These channels play a significant role in various physiological processes, including pain transmission, heart rhythms, and neuronal firing. By blocking these channels, these antagonists help reduce excitability, making them therapeutically valuable in conditions like epilepsy, pain, and cardiac arrhythmias.

In epilepsy, T-type calcium channel antagonists prevent abnormal neuronal firing, thereby reducing seizure frequency. These drugs also help alleviate chronic pain by modulating nociceptive signals in the nervous system. Furthermore, they regulate cardiac arrhythmias by stabilizing electrical activity in the heart and controlling irregular heartbeats. By selectively blocking T-type calcium channels, these drugs are crucial in managing these conditions effectively.

T-Type Calcium Channel Antagonists - Drug Pipeline Therapeutic Assessment

This section of the report covers the analysis of T-type calcium channel antagonist drug candidates based on several segmentations, including:

By Phase

  • Late-Stage Products (Phase 3 and Phase 4)
  • Mid-Stage Products (Phase 2)
  • Early-Stage Products (Phase I)
  • Preclinical and Discovery Stage Products

By Drug Class

  • Small Molecules
  • Monoclonal Antibodies
  • Others

By Route of Administration

  • Oral
  • Parenteral
  • Others

T-Type Calcium Channel Antagonists - Pipeline Assessment Segmentation, By Phases

The report covers phase I, phase II, phase III, phase IV, and early-phase drugs. The coverage includes an in-depth analysis of each drug across these phases. According to analysis, phase II cover a major share of the total T-type calcium channel antagonists clinical trials.

T-Type Calcium Channel Antagonists - Pipeline Assessment Segmentation, By Drug Classes

The drug molecule categories covered under the T-type calcium channel antagonists pipeline analysis include small molecules, monoclonal antibodies, and others. The report provides a comparative analysis of the drug classes for each drug in various phases of clinical trials for T-type calcium channel antagonists.

T-Type Calcium Channel Antagonists Clinical Trials Therapeutic Assessment - Competitive Dynamics

The report for the T-type calcium channel antagonists report insights includes the profile of key companies involved in clinical trials and their drugs under development. Below is the list of a few players involved in T-type calcium channel antagonists clinical trials:
  • Praxis Precision Medicines
  • Jazz Pharmaceuticals
  • Neurocrine Biosciences
  • Boehringer Ingelheim
  • Zalicus Pharmaceuticals
  • Taro Pharmaceutical

T-Type Calcium Channel Antagonists Emerging Drugs Profile

This section covers the detailed analysis of each drug under multiple phases, including phase I, phase II, phase III, phase IV, and emerging drugs for T-type calcium channel antagonists. It includes product description, trial ID, study type, drug class, mode of administration, and recruitment status of T-type calcium channel antagonist drug candidates.

60 mg Ulixacaltamide

Praxis Precision Medicines is sponsoring a Phase 3 decentralized study to evaluate the safety and efficacy of ulixacaltamide, a selective T-type calcium channel blocker, in treating essential tremor (ET). The study aims to compare ulixacaltamide with a placebo, assessing its safety and effectiveness. With an estimated 600 participants, the study is set to conclude by April 2025.

Suvecaltamide

The T-type calcium channel antagonists drug pipeline includes suvecaltamide (JZP385), an investigational, highly selective, and state-dependent modulator of T-type calcium channels, sponsored by Jazz Pharmaceuticals. It is presently in a Phase 2 study and under evaluation for its efficacy and safety in adult patients with essential tremor (ET) and moderate to severe residual tremor in Parkinson's disease. The study enrolls 160 participants.

Reasons To Buy This Report

The T-type Calcium Channel Antagonists Drug Pipeline Insight Report provides a strategic overview of the latest and future landscape of treatments for T-type calcium channel antagonists. It provides necessary information for making informed investment decisions along with research, development, and strategic planning efforts. The stakeholders will benefit from the essential insights into market trends, regulatory environments, and potential growth opportunities within T-type calcium channel antagonists pipeline insights.

Key Questions Answered in the T-Type Calcium Channel Antagonists - Pipeline Insight Report

  • Which companies/institutions are leading the T-type calcium channel antagonists drug development?
  • What is the efficacy and safety profile of T-type calcium channel antagonists pipeline drugs?
  • Which company is leading the T-type calcium channel antagonists pipeline development activities?
  • What is the current T-type calcium channel antagonists commercial assessment?
  • What are the opportunities and challenges present in the T-type calcium channel antagonists drug pipeline landscape?
  • What is the efficacy and safety profile of T-type calcium channel antagonists pipeline drugs?
  • Which company is conducting major trials for T-type calcium channel antagonists drugs?
  • Which companies/institutions are involved in T-type calcium channel antagonists collaborations aimed at providing enhanced therapeutic alternatives for patients?
  • What are the geographies covered for clinical trials in T-type calcium channel antagonists?

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Table of Contents

1 Preface
1.1 Introduction
1.2 Objectives of the Study
1.3 Research Methodology & Assumptions
2 Executive Summary
3 Overview of T-Type Calcium Channel Antagonists
3.1 Signs and Symptoms
3.2 Causes
3.3 Risk Factors
3.4 Diagnosis
3.5 Treatment
4 Patient Profile: T-Type Calcium Channel Antagonists
4.1 Patient Profile Overview
4.2 Patient Psychology and Emotional Impact Factors
4.3 Risk Assessment and Treatment Success Rate
5 T-Type Calcium Channel Antagonists: Epidemiology Snapshot
5.1 T-Type Calcium Channel Antagonists Incidence by Key Markets
5.2 T-Type Calcium Channel Antagonists - Patients Seeking Treatment in Key Markets
6 T-Type Calcium Channel Antagonists: Market Dynamics
6.1 Market Drivers and Constraints
6.2 SWOT Analysis
7 T-Type Calcium Channel Antagonists: Key Facts Covered
7.1 Top Countries Contributing to Clinical Trials in Asia-Pacific
7.2 Top Countries Contributing to Clinical Trials in Europe
7.3 Top Countries Contributing to Clinical Trials in North America
7.4 Top Countries Contributing to Clinical Trials in Other Regions
8 T-Type Calcium Channel Antagonists, Drug Pipeline Assessment
8.1 Assessment by Treatment Type
8.2 Assessment by Route of Administration
8.3 Assessment by Drug Class
9 Drug Pipeline Comparative Analysis
9.1 List of T-Type Calcium Channel Antagonists Pipeline Drugs
9.1.1 By Company
9.1.2 By Phase
9.1.3 By Indication
9.1.4 By Trial Status
9.1.5 By Funder Type
9.2 Attribute Scoring Analysis of Pipeline Drugs (Top Drugs)
10 T-Type Calcium Channel Antagonists Drug Pipeline - Late-Stage Products (Phase III and IV) (Top Drugs)
10.1 Comparative Analysis for Late-Stage Drugs
10.1.1 Study Type
10.1.2 Recruitment Status
10.1.3 Company
10.1.4 Funder Type
10.2 Product Level Analysis*
10.2.1 Drug: 60 mg Ulixacaltamide
10.2.1.1 Product Description
10.2.1.2 Trial ID
10.2.1.3 Sponsor Name
10.2.1.4 Study Type
10.2.1.5 Drug Class
10.2.1.6 Eligibility Criteria
10.2.1.7 Study Record Dates
10.2.1.7.1 First Submitted
10.2.1.7.2 First Posted
10.2.1.7.3 Last Update Posted
10.2.1.7.4 Last Verified
10.2.1.8 Indication
10.2.1.9 Study Design
10.2.1.10 Recruitment Status
10.2.1.11 Enrollment (Estimated)
10.2.1.12 Location Countries
10.2.1.13 Recent Results
10.2.2 Other Drugs
11 T-Type Calcium Channel Antagonists Drug Pipeline - Mid-Stage Products (Phase II) (Top Drugs)
11.1 Comparative Analysis for Mid-Stage Drugs
11.1.1 Study Type
11.1.2 Recruitment Status
11.1.3 Company
11.1.4 Funder Type
11.2 Product Level Analysis*
11.2.1 Drug: Suvecaltamide
11.2.1.1 Product Description
11.2.1.2 Trial ID
11.2.1.3 Sponsor Name
11.2.1.4 Study Type
11.2.1.5 Drug Class
11.2.1.6 Eligibility Criteria
11.2.1.7 Study Record Dates
11.2.1.7.1 First Submitted
11.2.1.7.2 First Posted
11.2.1.7.3 Last Update Posted
11.2.1.7.4 Last Verified
11.2.1.8 Indication
11.2.1.9 Study Design
11.2.1.10 Recruitment Status
11.2.1.11 Enrollment (Estimated)
11.2.1.12 Location Countries
11.2.1.13 Recent Results
11.2.2 Other Drugs
12 T-Type Calcium Channel Antagonists Drug Pipeline - Early-Stage Products (Phase I) (Top Drugs)
12.1 Comparative Analysis for Early-Stage Drugs
12.1.1 Study Type
12.1.2 Recruitment Status
12.1.3 Company
12.1.4 Funder Type
12.2 Product Level Analysis*
12.2.1 Drug 1
12.2.1.1 Product Description
12.2.1.2 Trial ID
12.2.1.3 Sponsor Name
12.2.1.4 Study Type
12.2.1.5 Drug Class
12.2.1.6 Eligibility Criteria
12.2.1.7 Study Record Dates
12.2.1.7.1 First Submitted
12.2.1.7.2 First Posted
12.2.1.7.3 Last Update Posted
12.2.1.7.4 Last Verified
12.2.1.8 Indication
12.2.1.9 Study Design
12.2.1.10 Recruitment Status
12.2.1.11 Enrollment (Estimated)
12.2.1.12 Location Countries
12.2.2 Other Drugs
13 T-Type Calcium Channel Antagonists Drug Pipeline - Preclinical and Discovery Stage Products (Top Drugs)
13.1 Comparative Analysis for Preclinical and Discovery Stage Drugs
13.1.1 Study Type
13.1.2 Recruitment Status
13.1.3 Company
13.1.4 Funder Type
13.2 Product Level Analysis*
13.2.1 Drug 1
13.2.1.1 Product Description
13.2.1.2 Trial ID
13.2.1.3 Sponsor Name
13.2.1.4 Study Type
13.2.1.5 Drug Class
13.2.1.6 Eligibility Criteria
13.2.1.7 Study Record Dates
13.2.1.7.1 First Submitted
13.2.1.7.2 First Posted
13.2.1.7.3 Last Update Posted
13.2.1.7.4 Last Verified
13.2.1.8 Indication
13.2.1.9 Study Design
13.2.1.10 Recruitment Status
13.2.1.11 Enrollment (Estimated)
13.2.1.12 Location Countries
13.2.2 Other Drugs
14 T-Type Calcium Channel Antagonists, Key Drug Pipeline Companies
14.1 Praxis Precision Medicines
14.1.1 Company Snapshot
14.1.2 Pipeline Product Portfolio
14.1.3 Financial Analysis
14.1.4 Recent News and Developments
14.2 Neurocrine Biosciences
14.2.1 Company Snapshot
14.2.2 Pipeline Product Portfolio
14.2.3 Financial Analysis
14.2.4 Recent News and Developments
14.3 Boehringer Ingelheim
14.3.1 Company Snapshot
14.3.2 Pipeline Product Portfolio
14.3.3 Financial Analysis
14.3.4 Recent News and Developments
14.4 Zalicus Pharmaceuticals
14.4.1 Company Snapshot
14.4.2 Pipeline Product Portfolio
14.4.3 Financial Analysis
14.4.4 Recent News and Developments
14.5 Taro Pharmaceutical
14.5.1 Company Snapshot
14.5.2 Pipeline Product Portfolio
14.5.3 Financial Analysis
14.5.4 Recent News and Developments
14.6 Jazz Pharmaceuticals
14.6.1 Company Snapshot
14.6.2 Pipeline Product Portfolio
14.6.3 Financial Analysis
14.6.4 Recent News and Developments
15 Regulatory Framework for Drug Approval, By Region16 Terminated or Suspended Pipeline Products