The neurodegenerative disease market size has grown strongly in recent years. It will grow from $52.3 billion in 2024 to $57.23 billion in 2025 at a compound annual growth rate (CAGR) of 9.4%. Growth in the historic period was driven by enhanced diagnostic capabilities, increased demand for symptomatic treatments, more clinical trial activity, strengthened public-private partnerships, and a growing burden of unmet medical needs.
The neurodegenerative disease market size is expected to see strong growth in the next few years. It will grow to $81.23 billion in 2029 at a compound annual growth rate (CAGR) of 9.2%. This anticipated growth is attributed to advancements in gene and cell therapy, increased use of digital biomarkers, a rise in precision medicine strategies, expansion of disease-modifying drug pipelines, and greater adoption of artificial intelligence in neurology. Notable trends expected during the forecast period include progress in neuroimaging technologies, advanced brain-targeted drug delivery systems, personalized treatment innovations, biomarker discovery breakthroughs, and advancements in gene editing techniques.
The increase in research and clinical trials is expected to propel the growth of the neurodegenerative disease market going forward. Clinical trials refer to research studies conducted with human participants to evaluate the safety, efficacy, and potential side effects of new treatments, drugs, or medical devices. The rise in research and clinical trials is primarily driven by the growing demand for new treatments to meet evolving healthcare needs and enhance patient outcomes. These trials play a crucial role in neurodegenerative disease research by generating essential data on the safety and effectiveness of new therapies, thereby advancing therapeutic development and improving patient care. For instance, in November 2023, according to a report published by the Association of the British Pharmaceutical Industry (ABPI), a UK-based association, the total number of industry clinical trials initiated annually in the UK rose slightly by 4.3%, from 394 trials in 2021 to 411 in 2022. Therefore, the increase in research and clinical trials is expected to drive the growth of the neurodegenerative disease market.
Major companies operating in the neurodegenerative disease market are focusing on developing innovative products such as next-generation adaptive Deep Brain Stimulation (aDBS) systems, aiming to improve treatment precision, enhance disease-modifying effects, and increase patient quality of life. Next-generation adaptive deep brain stimulation (aDBS) systems are advanced neurostimulation devices designed to deliver real-time, personalized treatment for Parkinson's disease by dynamically adjusting stimulation parameters based on neural feedback. This optimizes therapeutic effects and minimizes side effects, resulting in better patient outcomes. For example, in February 2025, Medtronic, a US-based medical technology company, received approval from the U.S. Food and Drug Administration (USFDA) for the world’s first adaptive deep brain stimulation (aDBS) system for Parkinson’s disease. This approval covers the premarket approval (PMA) application for the Percept RC neurostimulator with BrainSense technology, which automatically adjusts therapy in response to a patient’s brain signals. The system is clinically validated to provide symptom relief for advanced Parkinson’s disease patients and represents a major advancement in personalized neuromodulation therapies.
In December 2024, AbbVie, a US-based biopharmaceutical company, acquired Aliada Therapeutics for an undisclosed amount. Through this acquisition, AbbVie aims to advance potentially disease-modifying therapies for Alzheimer’s disease and enhance its neuroscience pipeline by utilizing Aliada’s innovative drug delivery platform capable of crossing the blood-brain barrier. Aliada Therapeutics is a US-based company that develops precision medicines for neurological disorders.
Major players in the neurodegenerative disease market are Pfizer Inc., Johnson & Johnson, F. Hoffmann-La Roche Ltd, AbbVie Inc., Sanofi S.A., Novartis AG, Takeda Pharmaceutical Company Limited, Eli Lilly and Company, Merck & Co. Inc., Biogen Inc., Neurocrine Biosciences Inc., Alnylam Pharmaceuticals Inc., Ionis Pharmaceuticals Inc., Cassava Sciences Inc., Denali Therapeutics Inc., Voyager Therapeutics Inc., AC Immune SA, Amylyx Pharmaceuticals Inc., Sage Therapeutics Inc., Alzheon Inc.
North America was the largest region in the neurodegenerative disease market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in neurodegenerative disease report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East and Africa.
The countries covered in the neurodegenerative disease market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain.
Neurodegenerative disease encompasses a group of disorders marked by the progressive deterioration of the structure and function of the nervous system, including the brain and spinal cord. The primary objective in this field is to understand, diagnose, and treat these conditions through advancements in biotechnology, pharmaceuticals, and medical technology. The aim is to slow disease progression, enhance patient outcomes, and lessen the burden on healthcare systems. This field also supports aging populations, improves neurological care, and contributes to a sustainable, technology-driven healthcare infrastructure.
The main types of neurodegenerative diseases include Parkinson's disease, Alzheimer's disease, multiple sclerosis, Huntington's disease, and amyotrophic lateral sclerosis. Parkinson's disease is a progressive neurological condition that impairs movement control due to the degeneration of dopamine-producing brain cells. These conditions are managed using various drug types such as N-methyl-D-aspartate (NMDA) receptor antagonists, cholinesterase inhibitors, dopamine agonists, and immunomodulatory drugs. Administration routes include oral, injectable, transdermal, and other methods. The drugs are distributed through hospital pharmacies, retail pharmacies, online pharmacies, and other distribution channels. Key end-users include hospitals, retail providers, and online platforms.
The neurodegenerative diseases market research report is one of a series of new reports that provides neurodegenerative diseases market statistics, including the neurodegenerative diseases industry global market size, regional shares, competitors with the neurodegenerative diseases market share, detailed neurodegenerative diseases market segments, market trends, and opportunities, and any further data you may need to thrive in the neurodegenerative diseases industry. This neurodegenerative diseases market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenarios of the industry.
The neurodegenerative disease market consists of revenues earned by entities through services such as biotechnology research, pharmaceutical development, diagnostic solutions, medical technologies, and patient care advancements aimed at understanding, diagnosing, and treating neurodegenerative conditions. The market value includes the value of related goods sold by the service provider or included within the service offering. The neurodegenerative disease market also includes sales of pharmaceuticals, biotechnology treatments, medical devices, and diagnostic tools aimed at managing and treating neurodegenerative conditions. Values in this market are ‘factory gate’ values, that is, the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors, and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.
The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD unless otherwise specified).
The revenues for a specified geography are consumption values and are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.
This product will be delivered within 3-5 business days.
The neurodegenerative disease market size is expected to see strong growth in the next few years. It will grow to $81.23 billion in 2029 at a compound annual growth rate (CAGR) of 9.2%. This anticipated growth is attributed to advancements in gene and cell therapy, increased use of digital biomarkers, a rise in precision medicine strategies, expansion of disease-modifying drug pipelines, and greater adoption of artificial intelligence in neurology. Notable trends expected during the forecast period include progress in neuroimaging technologies, advanced brain-targeted drug delivery systems, personalized treatment innovations, biomarker discovery breakthroughs, and advancements in gene editing techniques.
The increase in research and clinical trials is expected to propel the growth of the neurodegenerative disease market going forward. Clinical trials refer to research studies conducted with human participants to evaluate the safety, efficacy, and potential side effects of new treatments, drugs, or medical devices. The rise in research and clinical trials is primarily driven by the growing demand for new treatments to meet evolving healthcare needs and enhance patient outcomes. These trials play a crucial role in neurodegenerative disease research by generating essential data on the safety and effectiveness of new therapies, thereby advancing therapeutic development and improving patient care. For instance, in November 2023, according to a report published by the Association of the British Pharmaceutical Industry (ABPI), a UK-based association, the total number of industry clinical trials initiated annually in the UK rose slightly by 4.3%, from 394 trials in 2021 to 411 in 2022. Therefore, the increase in research and clinical trials is expected to drive the growth of the neurodegenerative disease market.
Major companies operating in the neurodegenerative disease market are focusing on developing innovative products such as next-generation adaptive Deep Brain Stimulation (aDBS) systems, aiming to improve treatment precision, enhance disease-modifying effects, and increase patient quality of life. Next-generation adaptive deep brain stimulation (aDBS) systems are advanced neurostimulation devices designed to deliver real-time, personalized treatment for Parkinson's disease by dynamically adjusting stimulation parameters based on neural feedback. This optimizes therapeutic effects and minimizes side effects, resulting in better patient outcomes. For example, in February 2025, Medtronic, a US-based medical technology company, received approval from the U.S. Food and Drug Administration (USFDA) for the world’s first adaptive deep brain stimulation (aDBS) system for Parkinson’s disease. This approval covers the premarket approval (PMA) application for the Percept RC neurostimulator with BrainSense technology, which automatically adjusts therapy in response to a patient’s brain signals. The system is clinically validated to provide symptom relief for advanced Parkinson’s disease patients and represents a major advancement in personalized neuromodulation therapies.
In December 2024, AbbVie, a US-based biopharmaceutical company, acquired Aliada Therapeutics for an undisclosed amount. Through this acquisition, AbbVie aims to advance potentially disease-modifying therapies for Alzheimer’s disease and enhance its neuroscience pipeline by utilizing Aliada’s innovative drug delivery platform capable of crossing the blood-brain barrier. Aliada Therapeutics is a US-based company that develops precision medicines for neurological disorders.
Major players in the neurodegenerative disease market are Pfizer Inc., Johnson & Johnson, F. Hoffmann-La Roche Ltd, AbbVie Inc., Sanofi S.A., Novartis AG, Takeda Pharmaceutical Company Limited, Eli Lilly and Company, Merck & Co. Inc., Biogen Inc., Neurocrine Biosciences Inc., Alnylam Pharmaceuticals Inc., Ionis Pharmaceuticals Inc., Cassava Sciences Inc., Denali Therapeutics Inc., Voyager Therapeutics Inc., AC Immune SA, Amylyx Pharmaceuticals Inc., Sage Therapeutics Inc., Alzheon Inc.
North America was the largest region in the neurodegenerative disease market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in neurodegenerative disease report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East and Africa.
The countries covered in the neurodegenerative disease market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain.
Neurodegenerative disease encompasses a group of disorders marked by the progressive deterioration of the structure and function of the nervous system, including the brain and spinal cord. The primary objective in this field is to understand, diagnose, and treat these conditions through advancements in biotechnology, pharmaceuticals, and medical technology. The aim is to slow disease progression, enhance patient outcomes, and lessen the burden on healthcare systems. This field also supports aging populations, improves neurological care, and contributes to a sustainable, technology-driven healthcare infrastructure.
The main types of neurodegenerative diseases include Parkinson's disease, Alzheimer's disease, multiple sclerosis, Huntington's disease, and amyotrophic lateral sclerosis. Parkinson's disease is a progressive neurological condition that impairs movement control due to the degeneration of dopamine-producing brain cells. These conditions are managed using various drug types such as N-methyl-D-aspartate (NMDA) receptor antagonists, cholinesterase inhibitors, dopamine agonists, and immunomodulatory drugs. Administration routes include oral, injectable, transdermal, and other methods. The drugs are distributed through hospital pharmacies, retail pharmacies, online pharmacies, and other distribution channels. Key end-users include hospitals, retail providers, and online platforms.
The neurodegenerative diseases market research report is one of a series of new reports that provides neurodegenerative diseases market statistics, including the neurodegenerative diseases industry global market size, regional shares, competitors with the neurodegenerative diseases market share, detailed neurodegenerative diseases market segments, market trends, and opportunities, and any further data you may need to thrive in the neurodegenerative diseases industry. This neurodegenerative diseases market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenarios of the industry.
The neurodegenerative disease market consists of revenues earned by entities through services such as biotechnology research, pharmaceutical development, diagnostic solutions, medical technologies, and patient care advancements aimed at understanding, diagnosing, and treating neurodegenerative conditions. The market value includes the value of related goods sold by the service provider or included within the service offering. The neurodegenerative disease market also includes sales of pharmaceuticals, biotechnology treatments, medical devices, and diagnostic tools aimed at managing and treating neurodegenerative conditions. Values in this market are ‘factory gate’ values, that is, the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors, and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.
The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD unless otherwise specified).
The revenues for a specified geography are consumption values and are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.
This product will be delivered within 3-5 business days.
Table of Contents
1. Executive Summary2. Neurodegenerative Disease Market Characteristics3. Neurodegenerative Disease Market Trends And Strategies4. Neurodegenerative Disease Market - Macro Economic Scenario Including The Impact Of Interest Rates, Inflation, Geopolitics, Trade Wars and Tariffs, And Covid And Recovery On The Market32. Global Neurodegenerative Disease Market Competitive Benchmarking And Dashboard33. Key Mergers And Acquisitions In The Neurodegenerative Disease Market34. Recent Developments In The Neurodegenerative Disease Market
5. Global Neurodegenerative Disease Growth Analysis And Strategic Analysis Framework
6. Neurodegenerative Disease Market Segmentation
7. Neurodegenerative Disease Market Regional And Country Analysis
8. Asia-Pacific Neurodegenerative Disease Market
9. China Neurodegenerative Disease Market
10. India Neurodegenerative Disease Market
11. Japan Neurodegenerative Disease Market
12. Australia Neurodegenerative Disease Market
13. Indonesia Neurodegenerative Disease Market
14. South Korea Neurodegenerative Disease Market
15. Western Europe Neurodegenerative Disease Market
16. UK Neurodegenerative Disease Market
17. Germany Neurodegenerative Disease Market
18. France Neurodegenerative Disease Market
19. Italy Neurodegenerative Disease Market
20. Spain Neurodegenerative Disease Market
21. Eastern Europe Neurodegenerative Disease Market
22. Russia Neurodegenerative Disease Market
23. North America Neurodegenerative Disease Market
24. USA Neurodegenerative Disease Market
25. Canada Neurodegenerative Disease Market
26. South America Neurodegenerative Disease Market
27. Brazil Neurodegenerative Disease Market
28. Middle East Neurodegenerative Disease Market
29. Africa Neurodegenerative Disease Market
30. Neurodegenerative Disease Market Competitive Landscape And Company Profiles
31. Neurodegenerative Disease Market Other Major And Innovative Companies
35. Neurodegenerative Disease Market High Potential Countries, Segments and Strategies
36. Appendix
Executive Summary
Neurodegenerative Disease Global Market Report 2025 provides strategists, marketers and senior management with the critical information they need to assess the market.This report focuses on neurodegenerative disease market which is experiencing strong growth. The report gives a guide to the trends which will be shaping the market over the next ten years and beyond.
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Description
Where is the largest and fastest growing market for neurodegenerative disease ? How does the market relate to the overall economy, demography and other similar markets? What forces will shape the market going forward? The neurodegenerative disease market global report answers all these questions and many more.The report covers market characteristics, size and growth, segmentation, regional and country breakdowns, competitive landscape, market shares, trends and strategies for this market. It traces the market’s historic and forecast market growth by geography.
- The market characteristics section of the report defines and explains the market.
- The market size section gives the market size ($b) covering both the historic growth of the market, and forecasting its development.
- The forecasts are made after considering the major factors currently impacting the market. These include:
- The forecasts are made after considering the major factors currently impacting the market. These include the Russia-Ukraine war, rising inflation, higher interest rates, and the legacy of the COVID-19 pandemic.
- Market segmentations break down the market into sub markets.
- The regional and country breakdowns section gives an analysis of the market in each geography and the size of the market by geography and compares their historic and forecast growth. It covers the growth trajectory of COVID-19 for all regions, key developed countries and major emerging markets.
- The competitive landscape chapter gives a description of the competitive nature of the market, market shares, and a description of the leading companies. Key financial deals which have shaped the market in recent years are identified.
- The trends and strategies section analyses the shape of the market as it emerges from the crisis and suggests how companies can grow as the market recovers.
Scope
Markets Covered:
1) By Disease Type: Parkinson's Disease; Alzheimer's Disease; Multiple Sclerosis; Huntington Disease; Amyotrophic Lateral Sclerosis2) By Drug Type: N-methyl-D-aspartate Receptor antagonists; Cholinesterase Inhibitors; Dopamine Agonists; Immunomodulatory Drugs; Acetylcholinesterase (AChE) Inhibitors; Antagonist, Monoamine Oxidase B (MAO-B) Inhibitor; Catechol-O-Methyltransferase (COMT) Inhibitor; Selective Serotonin Reuptake Inhibitor (SSRIs); Other Drug Types
3) By Route of Administration: Oral; Injectable; Transdermal; Other Routes Of Administration
4) By Distribution Channel: Hospital Pharmacies; Retail Pharmacies; Online Pharmacies; Other Distribution Channels
5) By End-User: Hospital; Retail; Online
Subsegment:
1) By Parkinson's Disease: Idiopathic Parkinson's Disease; Familial Parkinson's Disease; Early-Onset Parkinson's Disease; Parkinsonism2) By Alzheimer's Disease: Early-Onset Alzheimer's Disease; Late-Onset Alzheimer's Disease; Familial Alzheimer's Disease (FAD); Inflammatory Subtype; Non-Inflammatory Subtype; Cortical Subtype
3) By Multiple Sclerosis (MS): Clinically Isolated Syndrome (CIS); Relapsing-Remitting MS (RRMS); Secondary Progressive MS (SPMS); Primary Progressive MS (PPMS); Progressive-Relapsing MS (PRMS)
4) By Huntington's Disease: Adult-Onset Huntington's Disease; Juvenile Huntington's Disease
5) By Amyotrophic Lateral Sclerosis (ALS): Classical ALS; Limb-Onset ALS; Bulbar-Onset ALS; Respiratory-Onset ALS; Primary Lateral Sclerosis (PLS); Progressive Muscular Atrophy (PMA); Juvenile ALS; ALS-Parkinsonism-Dementia Complex (ALS-PDC)
Key Companies Profiled: Pfizer Inc.; Johnson & Johnson; F. Hoffmann-La Roche Ltd; AbbVie Inc.; Sanofi S.A.
Countries: Australia; Brazil; China; France; Germany; India; Indonesia; Japan; Russia; South Korea; UK; USA; Canada; Italy; Spain
Regions: Asia-Pacific; Western Europe; Eastern Europe; North America; South America; Middle East; Africa
Time Series: Five years historic and ten years forecast.
Data: Ratios of market size and growth to related markets, GDP proportions, expenditure per capita.
Data Segmentation: Country and regional historic and forecast data, market share of competitors, market segments.
Sourcing and Referencing: Data and analysis throughout the report is sourced using end notes.
Delivery Format: PDF, Word and Excel Data Dashboard.
Companies Mentioned
- Pfizer Inc.
- Johnson & Johnson
- F. Hoffmann-La Roche Ltd
- AbbVie Inc.
- Sanofi S.A.
- Novartis AG
- Takeda Pharmaceutical Company Limited
- Eli Lilly and Company
- Merck & Co. Inc.
- Biogen Inc.
- Neurocrine Biosciences Inc.
- Alnylam Pharmaceuticals Inc.
- Ionis Pharmaceuticals Inc.
- Cassava Sciences Inc.
- Denali Therapeutics Inc.
- Voyager Therapeutics Inc.
- AC Immune SA
- Amylyx Pharmaceuticals Inc.
- Sage Therapeutics Inc.
- Alzheon Inc.