The U.S. population health management market size was estimated at USD 43.69 Billion in 2025 and is projected to reach USD 210.18 billion by 2033, growing at a CAGR of 21.70% from 2025 to 2033. The market growth is majorly driven by the rising demand for healthcare IT services and solutions that support value-based healthcare delivery, resulting in a transition from Fee-For-Service (FFS) to a Value-Based Payment (VBP) model.
Increasing healthcare expenditure, the rising need for value-based healthcare, and effective disease management across different care settings are expected to drive the growth of the U.S. population health management industry. More than 130 million people in the U.S. suffer from at least one chronic condition. For instance, according to the data published by the Centers for Disease Control and Prevention (CDC) in February 2024, an estimated 129 million people in the U.S. live with at least one major chronic disease.
Population health management solutions based on open Application Programming Interfaces (APIs) are helpful for the management of chronic conditions with high treatment costs, such as cardiac diseases, asthma, and diabetes. PHM solutions also help reduce the cost of care, improve patient outcomes. PHM software also enables better analysis of patient data to make informed decisions.
Moreover, the implementation of population health management (PHM) facilitates the identification of at-risk patients and enhances disease prevention and management, resulting in financial savings. The Centers for Medicare & Medicaid Services (CMS) has introduced the Value-Based Payment Modifier to promote the adoption of PHM systems. This modifier offers varying payment rates to physician groups based on the quality of care provided, rather than the cost of care incurred during their performance period.
In the U.S., providers, payers, and accountable care organizations promote PHM systems. Many providers and payers require upgrading and automating their healthcare management systems, which is anticipated to improve healthcare delivery and help departments collaborate. The providers mainly focus on chronic diseases, such as diabetes and cardiovascular disorders, which are generally responsible for significant healthcare costs. The rising prevalence of lifestyle disorders has increased the need for effective management of the disease burden on healthcare centers.
Furthermore, key players are engaged in strategic initiatives, such as the launch of new products, partnerships and collaborations, mergers and acquisition activities, etc., which contribute to market growth. For instance, in May 2025, Oracle, the Cleveland Clinic, and G42 announced a strategic partnership to develop an AI-based global healthcare platform. This platform will leverage AI, large-scale data analytics, and clinical expertise to deliver scalable, affordable care models, enhancing patient outcomes, precision medicine, and public health management across the U.S. and UAE.
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Increasing healthcare expenditure, the rising need for value-based healthcare, and effective disease management across different care settings are expected to drive the growth of the U.S. population health management industry. More than 130 million people in the U.S. suffer from at least one chronic condition. For instance, according to the data published by the Centers for Disease Control and Prevention (CDC) in February 2024, an estimated 129 million people in the U.S. live with at least one major chronic disease.
Population health management solutions based on open Application Programming Interfaces (APIs) are helpful for the management of chronic conditions with high treatment costs, such as cardiac diseases, asthma, and diabetes. PHM solutions also help reduce the cost of care, improve patient outcomes. PHM software also enables better analysis of patient data to make informed decisions.
Moreover, the implementation of population health management (PHM) facilitates the identification of at-risk patients and enhances disease prevention and management, resulting in financial savings. The Centers for Medicare & Medicaid Services (CMS) has introduced the Value-Based Payment Modifier to promote the adoption of PHM systems. This modifier offers varying payment rates to physician groups based on the quality of care provided, rather than the cost of care incurred during their performance period.
In the U.S., providers, payers, and accountable care organizations promote PHM systems. Many providers and payers require upgrading and automating their healthcare management systems, which is anticipated to improve healthcare delivery and help departments collaborate. The providers mainly focus on chronic diseases, such as diabetes and cardiovascular disorders, which are generally responsible for significant healthcare costs. The rising prevalence of lifestyle disorders has increased the need for effective management of the disease burden on healthcare centers.
Furthermore, key players are engaged in strategic initiatives, such as the launch of new products, partnerships and collaborations, mergers and acquisition activities, etc., which contribute to market growth. For instance, in May 2025, Oracle, the Cleveland Clinic, and G42 announced a strategic partnership to develop an AI-based global healthcare platform. This platform will leverage AI, large-scale data analytics, and clinical expertise to deliver scalable, affordable care models, enhancing patient outcomes, precision medicine, and public health management across the U.S. and UAE.
U.S. Population Health Management Market Report Segmentation
This report forecasts revenue growth and provides an analysis of the latest trends in each of the sub-segments from 2021 to 2033. For this report, the analyst has segmented the U.S. population health management market report based on product, delivery mode, and end use:Product Outlook (Revenue, USD Million, 2021-2033)
- Software
- Services
Delivery Mode Outlook (Revenue, USD Million, 2021-2033)
- On-Premise
- Cloud-based
End Use Outlook (Revenue, USD Million, 2021-2033)
- Providers
- Payers
- Employer Groups
Why should you buy this report?
- Comprehensive Market Analysis: Gain detailed insights into the market across major regions and segments.
- Competitive Landscape: Explore the market presence of key players.
- Future Trends: Discover the pivotal trends and drivers shaping the future of the market.
- Actionable Recommendations: Utilize insights to uncover new revenue streams and guide strategic business decisions.
This report addresses:
- Market intelligence to enable effective decision-making
- Market estimates and forecasts from 2018 to 2030
- Growth opportunities and trend analyses
- Segmental and regional revenue forecasts for market assessment
- Competition strategy and market share analysis
- Product innovation listings for you to stay ahead of the curve
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Table of Contents
Chapter 1. Methodology and Scope
Chapter 2. Executive Summary
Chapter 3. Population Health Management Market Variables, Trends & Scope
Chapter 4. U.S. Population Health Management Market: Product Estimates & Trend Analysis
Chapter 5. U.S. Population Health Management Market: Delivery Mode Estimates & Trend Analysis
Chapter 6. U.S. Population Health Management Market: End Use Estimates & Trend Analysis
Chapter 7. U.S. Population Health Management Market - Competitive Analysis
List of Tables
List of Figures
Companies Mentioned
The leading players profiled in this U.S. Population Health Management market report include:- eradigm LLC.
- racle
- onifer Health Solutions, LLC
- ClinicalWorks
- nli Health Intelligence
- cKesson Corp.
- edecision
- ptum, Inc.
- dvisory Board
- oninklijke Philips N.V.
- thenahealth, Inc.
- edBrick Health
- elltok
Table Information
| Report Attribute | Details |
|---|---|
| No. of Pages | 100 |
| Published | September 2025 |
| Forecast Period | 2025 - 2033 |
| Estimated Market Value ( USD | $ 43.69 Billion |
| Forecasted Market Value ( USD | $ 210.18 Billion |
| Compound Annual Growth Rate | 21.7% |
| Regions Covered | United States |
| No. of Companies Mentioned | 14 |
