Eye Melanoma Unveiled: Cutting-Edge Diagnosis, Revolutionary Treatments and Advanced Drug Delivery delves into the latest advancements in drug delivery systems for diagnosing and treating eye melanoma. Compiled by leading scientists globally, the book thoroughly examines innovative drug delivery techniques utilized in uveal melanoma treatments, beginning with an overview of the disease's epidemiology, risk factors, pathogenesis, and molecular mechanisms. The book further discusses imaging techniques and diagnostic methods essential for precise disease identification.
Despite stable incidence rates over the past thirty years and enhanced local treatments, survival rates for uveal melanoma have not notably improved. Recent genetic and cytogenetic developments have improved prognostication and cancer identification with high metastatic potential. This book is invaluable for specialists in drug formulation and delivery, eye oncologists, translational researchers, and life scientists.
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Table of Contents
Chapter 1: Introduction to eye melanoma: Pathogenesis, diagnosis, and current treatment modalitiesPavithra Kothapalli, Manimaran Vasanthan and Devesh U Kapoor
Chapter 2: Eye melanoma: Epidemiology and risk factors
Shama Mujawar, Durairaj Vijayasarathi, Tanishqa Annam, Tanaya Deshpande, Abha Prabhune, Aarohi Deshpande and Bhupendra G. Prajapati
Chapter 3: Fundamentals of nano drug delivery systems: Principles and applications in ocular oncology
Biswajit Basu, Monosiz Rahaman and Bhupendra G. Prajapati
Chapter 4: Diagnostic nanoprobes for early detection and monitoring of eye melanoma progression
Lucy Mohapatra, Ayushi Singh, Deepak Mishra, Alok S Tripathi, Sambit Kumar Parida and Bhupendra G. Prajapati
Chapter 5: Liposomal formulation for the diagnosis and treatment of eye melanoma
Biswajit Basu, Monosiz Rahaman and Bhupendra G. Prajapati
Chapter 6: Polymeric nanoparticles for the diagnosis and treatment of eye melanoma
Kavyashree Shetty and Saritha Shetty
Chapter 7: Role of hydrogel for the diagnosis and treatment of eye melanoma
Anindita De, Marjita Chakma, Kanika Singh, Shivam Singh and Young Joon Park
Chapter 8: Application of quantum dots for the diagnosis and treatment of eye melanoma
Himanshu Paliwal, Akanksha Kasture, Pratiksha Khedkar, Tejas Rangbhal and Bhupendra G. Prajapati
Chapter 9: Nanoscale drug-eluting implants for the diagnosis and treatment of eye melanoma
Akruti Khodakiya, Chelsi Gadhvi, Bhupendra G. Prajapati and Ashish Wadhwani
Chapter 10: Nanoparticles conjugated with targeting ligands for the diagnosis and treatment of eye melanoma
Nidhi Trivedi, Vidhi Pandya, Amit A. Patel, Viral A. Patel, Bhupendra G. Prajapati, Samir G. Patel and Ravish J. Patel
Chapter 11: Treatment modalities: Surgery and radiotherapy for eye melanoma
Sridevi S, Dhivya L. S, Ankul Singh. S, Monisha A, Harikrishnan N and Bhupendra G. Prajapati
Chapter 12: Emerging therapies: Targeted and immunotherapy for eye melanoma
Neelakanta Sarvashiva Kiran, Chandrashekar Yashaswini, Ankita Chatterjee and Bhupendra G. Prajapati
Chapter 13: Biomarkers for detection of eye melanoma
Ranjan Kumar Singh, Chennu M.M Prasada Rao, Vaibhav Saxena, Komal Sharma, Vivek Jain, Rajeswari Tanniru and Devesh U. Kapoor
Chapter 14: Eye melanoma: Management of metastatic disease
Mayur B. Kale, Nitu L. Wankhede, Rupali S. Pawar, Aman B. Upaganlawar, Brijesh G. Taksande, Milind J. Umekar, Sushruta Koppula and Spandana Rajendra Kopalli
Chapter 15: Precision medication in therapy of eye melanoma
Neelakanta Sarvashiva Kiran, Chandrashekar Yashaswini, Ankita Chatterjee and Bhupendra G. Prajapati
Authors
Bhupendra G. Prajapati Parul Institute of Pharmacy, Faculty of Pharmacy, Parul University, Waghodia, Vadodara, Gujarat, India. Dr. Bhupendra Gopalbhai Prajapati is Professor (Research Cadre) at Parul Institute of Pharmacy, Parul University, Gujarat, India, and serves as Adjunct Professor in the Department of Industrial Pharmacy at Silpakorn University, Thailand. His academic, research, and industry expertise focuses on lipid-based formulations, nano- and microparticulate drug delivery systems, and strategies to enhance drug bioavailability. Dr. Prajapati has received several academic and professional honors recognizing excellence in teaching and research. He has made substantial scholarly contributions through research and review publications, book chapters, and edited volumes in pharmaceutical sciences. Actively engaged in postgraduate and doctoral mentoring, he supports research training in advanced drug delivery and formulation science. Dr. Prajapati also serves in editorial and section-editor roles for international scientific publications, contributing to the advancement and quality of pharmaceutical research dissemination. Devesh U. Kapoor Professor, Dr. Dayaram Patel Pharmacy College, Bardoli, Gujarat, India. Dr. Devesh U. Kapoor is Professor of Pharmaceutics at Dr. Dayaram Patel Pharmacy College, Bardoli, Gujarat, affiliated with Gujarat Technological University. His academic and research expertise centers on pharmaceutics, nanodrug delivery, and modified-release drug delivery systems. Dr. Kapoor has made extensive scholarly contributions through research and review publications, book chapters, and edited volumes with international publishers. He is actively involved in postgraduate and doctoral research supervision in advanced drug delivery technologies. His editorial experience includes serving in senior editorial roles for international journals across pharmacology, pharmaceutics, and biomedical sciences, along with regular peer-review activity for a wide range of scientific journals. Dr. Kapoor has also secured competitive research and academic development funding and is a frequent invited speaker at national scientific meetings, workshops, and academic programs. Nemat Ali King Saud University, Saudi Arabia.Currently working as an Assistant Professor in the Department of Pharmacology and Toxicology at College of Pharmacy King Saud University, Riyadh Saudi Arabia. Before joining King Saud University worked as a Post-Doctoral Scholar in the School of Medicine, University of Kentucky, Lexington, USA.. Currently involved in teaching, research, and research is mainly focused on finding the molecular mechanisms involved in cancer chemoprevention and chemotherapy-induced vital organ toxicity and their prevention using natural and synthetic compounds using in-vivo and in-vitro models. He has published more than 130 research, review and book chapters in highly reputed international journals.
