Biofabrication and Synthetic Biology in Medicinal Plants: Advances in Biotechnology and Breeding presents recent technological advances for enhancing medicinal plants as sources of plant-based biopharmaceuticals. It covers biofabrication, synthetic biology, modern biotechnological tools, and innovative breeding strategies tailored for medicinal plant improvement. While these technologies are well established in crop plants, their application in medicinal plants remains underexplored. Medicinal plants are rich sources of therapeutic compounds traditionally used across cultures to treat a wide range of diseases and health conditions. These plants produce diverse bioactive molecules, including terpenoids, flavonoids, alkaloids, and phenolics, many of which exhibit significant pharmacological potential. For centuries, medicinal and aromatic plants have played a vital role in human healthcare and continue to be valued globally. Recent advances in synthetic biology, metabolic engineering, and biotechnology promise to enhance the production, quality, and efficacy of these bioactive compounds, addressing unmet medical needs and contributing to sustainable healthcare. This book compiles insights from leading experts, offering a comprehensive reference for researchers, early-career scientists, students, and professionals working in medicinal plant biotechnology and breeding.
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Table of Contents
1 Medicinal plants: Ancient practice for eradication of global diseases2 Bioactive compounds of medicinal plants and their role in preventing infectious diseases
3 Conservation of medicinal and aromatic plants: Current efforts, challenges and future perspectives
4 Biofabrication of nanoparticles from medicinal plants: Challenges and future perspectives
5 Intellectual property right law and traditional knowledge of medicinal plants
6 Biotechnological production of phytoconstituents to pure molecules
7 Conventional and advanced methods of phyto-constituent recovery
8 Green synthesis of nanoparticles and technological advances in analysis of biofabricated nanoparticles
9 Combinatorial approaches of MAPs and nanotechnology and its applications
10 In silico prediction tools of plant-based precision medicine
11 Biotechnological paradigms for augmenting secondary metabolite biosynthesis in medicinal flora
12 Genetic innovations shaping medicinal plant research: Advancements in genomic variability and architecture
13 Advances in plant tissue culture techniques for rapid propagation and conservation of medicinally valuable plant species
14 Manipulating biosynthetic pathways for controlled secondary metabolite production
15 Perspectives, problems, and possible solutions in Nutriomics and Ayurgenomics of medicinal plants with case studies
16 Utilization of computational resources for genomic data mining and integration in medicinal plant breeding initiatives
17 Bioengineering of plant natural products: Concepts and processes in synthetic biology
18 Role of synthetic biology in biodrug production and human wellness
19 Synthetic biology based production systems of bioactive compounds
20 Synthetic biology based reconstruction of pathway
21 Next-generation sequencing (NGS) techniques in improvement of medicinal plants
Authors
Eti Sharma Assistant Professor, Gautam Buddha University, India.Dr. Eti Sharma is currently working as Assistant Professor, School of Biotechnology, Gautam Buddha University, Greater Noida, India. She holds a Ph.D. degree in Molecular Biology & Biotechnology from G.B. Pant University of Agriculture & Technology, Pantnagar. She established herself in the field of bioprospecting and metabolomics of medicinal plants. She has expertise in medicinal plants research, biofabrication and her current research interest lies in plant-microbe interactions in medicinal plants. She is also working on more edited book proposals. She has authored many research papers, book chapters and popular articles in nationally and internationally reputed journals.
Gunjan Tiwari Scientist, Central Institute of Medicinal and Aromatic Plants, Lucknow, India.Dr. Gunjan Tiwari is working as Scientist C in the Division of Plant Breeding and Genetic Resource Conservation, CSIR-CIMAP-Lucknow, India. She has completed her Ph.D. (Genetics and Plant Breeding) from GB Pant University of Agriculture and Technology, Pantnagar. She has significantly contributed to the field of Population Genetics and Breeding, where she characterized the structure of breeding populations of various field and horticultural crops using second and third-generation molecular markers. She is actively involved in understanding the genetics of economic traits of medicinal and aromatic plants of global significance and using various selection methods to maximize genetic gain. She has authored many research articles in internationally reputed journals.
Deepali Singh Assistant Professor, Gautam Buddha University, Greater Noida, India. Dr. Deepali Singh serves as Assistant Professor, School of Biotechnology, Gautam Buddha University, Greater Noida, India. She achieved her doctoral degree from Delhi University, India. She did her postdoctoral work at The Ohio State University, Columbus, USA. She was trained in studying RNA-protein interactions of RNAse P. She also studied the RNA structure of the retroviral post-transcriptional element and its role in regulating viral transcription and translation. She has extensive training and experience of more than two decades of working in plant molecular biology and biotechnology. Her current research interests lie in the field of genomics and genome engineering for studying plant-pathogen interactions. She has authored several research papers in internationally reputed journals.
