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Hematological Insights and Clinical Implications of Platelet Functions in Lymphatic Filariasis

  • Book

  • February 2026
  • Elsevier Science and Technology
  • ID: 6250496

Hematological Insights and Clinical Implications of Platelet Functions in Lymphatic Filariasis is a groundbreaking resource that delves into the impact of filarial parasites on platelet functions in humans. This comprehensive work explores the intricate signaling and immunological pathways affected by these interactions, filling a significant gap in the existing literature. The book is particularly valuable for researchers, scientists, and clinicians involved in the management and study of lymphatic filariasis, commonly known as elephantiasis; and also human platelets. With limited prior information on the interplay between human platelets and filarial parasites, this text offers a fresh perspective that could enhance patient management strategies. By understanding these interactions, healthcare professionals may unlock new avenues for effective treatment and prevention of lymphatic filariasis. This book is essential for anyone looking to deepen their understanding of the disease and contribute to its potential elimination.

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Table of Contents

  1. Introduction to lymphatic filariasis
  2. Global burden of lymphatic filariasis
  3. Pathogenesis and hematological findings in lymphatic filariasis
  4. Immunology related to chronic edema, inflammation, and their cardiovascular effects
  5. Platelet biology and functions
  6. Impact of lymphatic filariasis on platelet count and functions and their biochemical and molecular mechanisms
  7. Role of immunomodulation in the pathogenesis of filariasis
  8. Prevention and therapeutic interventions of lymphatic filariasis
  9. Future directions of research on platelet function in lymphatic filariasis

Authors

Jyotsna Kailashiya Banaras Hindu University, India. Prof. Jyotsna Kailashiya completed her post graduation (MD) and PhD in Medical Biochemistry and has been working in the Department of Biochemistry, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India as faculty since 2015. She has expertise in clinical and medical biochemistry, blood investigations, flow cytometry, confocal microscopy, proteomics and platelet function assays. Her area of research includes platelet biology and analysis of different aspects of platelet functions related to human health and diseases. Her lab is focused on clinical and experimental research on platelet functions and signaling and their effects on pathogenesis of various diseases.