Epigenetic Regulations in Gastrointestinal Cancers

Table of Contents

1 Epigenetics of GI cancers
2 Overview of epigenetic changes in cancer-related to gastrointestinal systems
3 Epigenetic change-based cancer development in the gastrointestinal gastric, pancreatic, and colorectal cancers
4 Epigenetics in gastrointestinal cancers
5 Targeting methylation and acetylation in colon cancer
6 Epigenetics in angiogenesis, gastrointestinal cancer progression and its clinical significance
7 Non-coding RNAs
8 The roles of non-coding RNA-encoded functional peptides in gastrointestinal cancer
9 Targeting methylation and acetylation in colon cancer
10 Deciphering the crosstalk between single cell sequencing and gastrointestinal cancer
11 Exosome-derived biomarkers and therapies
12 Therapeutic challenges and advances in the management of colorectal cancer overcoming resistance mechanisms and exploring future directions
13 Current and emerging epigenetic therapies and future directions
14 Phytochemicals as epigenetic modulators in gastrointestinal cancer
15 Epigenetics and metabolic involvement in regeneration: An overview
16 The role of DNA methyltransferase genes in cancers: A systematic review and meta-analysis of DNMT1 and DNMT3B gene polymorphisms
17 Epigenetic and post-transcriptional regulators of colon cancer formation vs progression invasion and metastasis
18 Role of the microbiome on epigenetic changes in pancreatic and colon cancers
19 DNA methylation and histone modifications in gastrointestinal cancers
20 Epigenetic mechanisms in colorectal cancer: Preclinical studies to clinical implications
21 DNA methylation and histone modification in liver cancer

Authors

Ganji Purnachandra Nagaraju Assistant Professor, School of Medicine, Division of Hematology and Oncology, University of Alabama, Birmingham, AL, USA. Dr. Nagaraju obtained his MSc and his PhD, both in Biotechnology, from Sri Venkateswara University in Tirupati, Andhra Pradesh, India. He received his DSc from Berhampur University in Berhampur, Odisha, India. Dr. Nagaraju's research focuses on translational projects related to gastrointestinal malignancies. He has published over 100 research papers in highly reputed international journals and has presented more than 50 abstracts at various national and international conferences. Dr. Nagaraju is author and editor of several published books for Elsevier and Springer Nature. He serves as editorial board member of several internationally recognized academic journals. Dr. Nagaraju has received several international awards including FAACC. He also holds memberships with the Association of Scientists of Indian Origin in America (ASIOA), the Society for Integrative and Comparative Biology (SICB), The Science Advisory Board, The RNA Society, The American Association for Clinical Chemistry (AACC) and the American Association of Cancer Research (AACR). Seema Kumari GITAM University, India. Dr. Seema Kumari is a Scientist in the Department of Biochemistry and Bioinformatics at GITAM University, where she earned her PhD in Biochemistry. With a strong focus on cancer research, her work explores cancer initiation, progression, metastasis, oxidative stress, and phytochemical-based anticancer drugs. Dr. Seema is dedicated to translating her research into practical applications, as demonstrated by her 56 publications in esteemed peer-reviewed journals and presentations at national and international conferences. She has secured government funding from the University Grants Commission (UGC) in New Delhi, India, to support her research initiatives. In addition to her research, Dr. Seema actively engages with the academic community by serving as a reviewer and guest editor for reputable journals and is a member of the Indian Association of Cancer Research. Her contributions significantly advance the field of biochemistry and cancer research.