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The Immunology of Horses and Donkeys

  • Book

  • August 2026
  • Elsevier Science and Technology
  • ID: 6251589
The Immunology of Horses and Donkeys offers a comprehensive overview of the immune systems of equids, bridging a critical gap by combining current research with foundational concepts and emphasizing both mechanisms and practical applications. The book covers immune development, disease resistance, vaccination, and immune disorders, supporting improved health management in horses and donkeys. Organized logically, it begins with the evolutionary history and domestication of equids and then explores immune ontogeny, innate and adaptive responses, and lymphoid tissue structure. Chapters detail the major histocompatibility complex, cytokine signaling, antigen-presenting cells, and mucosal immunity.

Additional sections address the microbiota, vaccine strategies, and immune responses to bacterial, viral, and parasitic infections, providing a holistic view of equine immune health. Users will find content that advances understanding in immunology, biomedical research, and veterinary medicine, supporting the development of better diagnostics, vaccines, and therapies. The book's clear, thorough approach benefits both scientific discovery and clinical application, ultimately improving equine health and informing broader mammalian immunology studies.

Table of Contents

1. The Evolution and Domestication of the Horse
2. Foal Ontogeny, Reproduction, and Lactation
3. Innate Immunity in the Horse
4. The Hematology of Horses and Donkeys
5. The Equine Sickness Response
6. Equine Cytokines
7. Antigen Processing Cells
8. The Lymphoid Organs of the Horse.
9. ELA -The Equine Major Histocompatibility Complex.
10. Equine Innate Lymphoid Cells
11. The Equine B Cell System
12. The Equine T Cell System
13. Immunity on Equine Body Surfaces
14. The Microbiota and the Equine Immune System.
15. Horse and Donkey Vaccines and Vaccination
16. Immunity to Selected Bacterial Diseases of Equids
17. Immunity to Selected Viral diseases of Equids
18. Immunity to Selected Equine Parasites
19. Equine Anaphylaxis and Allergic Diseases
20. Other Hypersensitivity Diseases of Equids
21. Immunity and Equine tumors
22. Equine Inflammatory Diseases
23. Equine autoimmune diseases
24. Equine Immunodeficiency Diseases
25. The effects of intensive exercise on equine immunity.
26. Equine Immunosenescence

Authors

Ian R. Tizard University Distinguished Professor of Immunology Emeritus, Department of Veterinary Pathobiology, Texas A&M University, College Station, Texas, USA.

Ian R. Tizard, BVMS, BSc, PhD, DSc (Hons), DACVM, is a Diplomate of the American College of Veterinary Microbiologists and a University Distinguished Professor Emeritus of Immunology, Department of Veterinary Pathobiology, The Texas Veterinary Medical Center at Texas A &M University (TAMU), College Station, Texas, USA. Dr. Tizard earned his Bachelor of Veterinary Medicine and Surgery from the University of Edinburgh, Scotland, in 1965. He then completed a Bachelor of Science in Pathology and a PhD in Immunology. After completing his studies, Dr. Tizard became a Post-Doctoral Fellow at the University of Guelph, where he remained as a professor until 1982 when he moved to TAMU. Dr. Tizard wrote the first standardized textbook on Veterinary Immunology in 1977. This text, now in its 11th edition, is used worldwide, and has played a major role in establishing Immunology among the key disciplines.