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Insights and Implications of Pseudo Esterase Activity of Human Serum Albumin in Diabetic Kidney Disease

  • Book

  • August 2026
  • Elsevier Science and Technology
  • ID: 6251620
Insights and Implications of Pseudo Esterase Activity of Human Serum Albumin in Diabetic Kidney Disease provides a comprehensive exploration of diabetic nephropathy, emphasizing the critical need for early detection methods prior to the onset of microalbuminuria. The book's primary focus is on the study of pseudoesterase activity in urinary albumin and other proteins as a potential biomarker for early diagnosis of diabetic kidney disease. This resource bridges a significant gap in current literature by providing an in-depth analysis of how this enzymatic activity can inform the classification and management of diabetic nephropathy.

Chapters cover foundational knowledge of diabetes and its complications, the mechanisms of diabetic nephropathy, and detailed discussions on human serum albumin and its enzymatic activities. Each chapter covers the biochemical characterization of pseudoesterase activity, methods for its detection, and the significance of urinary proteomic profiling. Final chapters highlight future research opportunities and the potential for developing point-of-care testing tools, positioning this work as a critical resource for advancing the field of diabetic kidney disease research and clinical practice.

Table of Contents

1. Diabetes Mellitus and Its Complications
2. Diabetic Nephropathy and Microalbuminuria as Its Biomarker
3. Human Serum Albumin and Its Enzymatic Activities
4. Pseudoesterase Activity of Human Serum Albumin
5. Methods for Detecting Pseudoesterase Activity of Human Serum Albumin
6. Urinary Proteomic Profiling in Diabetic Nephropathy and the Importance of Understanding Enzymatic Profiles
7. Urinary Pseudoesterase Activity of Human Serum Albumin as a Promising Biomarker of Diabetic Nephropathy
8. Future Directions and Research Opportunities

Authors

Dibyajyoti Banerjee Professor and Head, of the Department of Experimental Medicine and Biotechnology at the Postgraduate Institute of Medical Education and Research, India. Dr Dibyajyoti Banerjee passed MBBS from North Bengal Medical College, Darjeeling, West Bengal, India in 1999 with Honors in Physiology and Biochemistry and a Gold Medal in Pathology. He was awarded an MD (Biochemistry) from Kasturba Medical College, Manipal, Karnataka, India in 2003. During the study of MD(Course), he established urinary hydrogen peroxide as a biomarker of malignancies. He is an expert in biochemistry in with research expertise in human serum albumin and POCT development. Currently, he is interested in the esterase activity of albumin and recently while working as Professor and Head, of the Department of Experimental Medicine and Biotechnology at the Postgraduate Institute of Medical Education and Research, Chandigarh, India his team discovered that pseudo esterase activity of human serum albumin has the potential to screen microalbuminuria for diagnosis of diabetic nephropathy. He has over 10 years of research experience and published ~40 articles.