Immunomodulators Part B brings together a curated set of research-focused chapters that explore how the immune system is influenced by microbes, immune checkpoint molecules, genetic regulation, and emerging therapeutic strategies. It covers the role of the microbiome and microbial products in shaping immune responses relevant to gastrointestinal cancers, examines VISTA as a “double-edged” checkpoint in cancer and autoimmunity, and uses bioinformatics to uncover immune-modulatory patterns in HPV-associated head and neck squamous cell carcinoma and bladder cancer.
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Table of Contents
1. Microbiome and microbial products as immunomodulators: Implications for gastrointestinal cancersShriyans Reddy Yendreddy, Divya Patchigolla, Satyendra Singh, Kirti Baghel, Rupal Ojha, and Vijay Kumar Prajapati
2. VISTA as a Double-Edged immune checkpoint molecule in cancer and autoimmunity
Ali Mert Sencer and Sibel Kalyoncu
3. Investigating the immune modulatory association of miRNAs in HPV-associated HNSCC individuals: A bioinformatics approach
Ankur Datta, M. Muthu Meenakshi, Susanna Daniels, B. Varsha, and C. George Priya Doss
4. Transcriptomic Insights into Epigenetic and Immunomodulatory Roles of Nuclear Histone Genes in Bladder Cancer: A Bioinformatics Approach
Santhosh Mudipalli Elavarasu, Insha Asheem, Nihla M, Udhaya Kumar. S, R. Magesh, Sasikumar K, and George Priya Doss C
5. Identification of Common Hub Genes and Pathways in Systemic Lupus Erythematosus and Cervical Cancer Using Bioinformatics Approach
Tamizhini Loganathan, Madhulekha, Hatem Zayed, and George Priya Doss C
6. Transcriptomic Profiling Reveals Immune Pathway Dysregulation and Key Interferon-Responsive Genes in Systemic Lupus Erythematosus
Prasanna Kumar Selvam, Supraja Mohan and Karthick Vasudevan
7. Peptides and Peptidomimetics as Immunomodulator Agents Targeting Neglected Tropical Diseases
Sheila Oliveira de Souza, Leandro Rocha Silva, Manuele Figueiredo da Silva,
Maria Gabriele Cordeiro Domingos, Eziane Dantas da Silva, Jo�o Xavier de Ara�jo-J�nior, Paulo Fernando da Silva Santos-J�nior, Ana Catarina Rezende Leite, and
Edeildo Ferreira da Silva J�nior
8. Aptamers as immunomodulatory therapeutic alternatives targeting Neglected Tropical Diseases (NTDs)
Leandro Rocha Silva, Wadja Feitosa dos Santos Silva, Ana Clara Ferreira de Melo,
�rica Erlanny da Silva Rodrigues, and Edeildo Ferreira da Silva-J�nior
