New developments in mass spectrometry have allowed routine identification and lowered limits of detection at levels only imagined a decade ago. Thousands of contaminants and residues in the food supply and the environment are now being reported. Between 2005 and 2010, more than 5,000 publications covering TOF-MS and environmental and food analysis were published, showing the importance of the technique in these applications.
This book covers the basic principles of method development in GC- and LC-TOF-MS as well as the main operational parameters related to TOF-MS. The second part focuses on the relevant environmental applications, including quality control aspects as well as data collection. The third part is devoted to relevant applications in food analysis, including validation procedures for screening analysis as well as relevant databases.
- Outlines basic concepts and principles of gas and liquid chromatography TOF-MS and its application in food analysis
- Includes quality control and data collection techniques
- Focuses on environmental implications and safety concerns
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1. Application of HPLC-ToF-MS and HPLC-QToF-MS/MS for Pesticide Residues Analysis in Fruit and Vegetable Matrices 2. Chemical Evaluation of Water Treatment Processes by LC-(Q)Tof-MS. Identification of Transformation Products 3. Selected Applications of Accurate Mass Determinations Using LC-Tof-MS for Toxic Compounds in Animal Origin Products 4. High Mass Resolution vs MS/MS 5. Time of Flight Mass Spectrometry vs Orbitrap Based Mass Spectrometry for the Screening and Identification of Drugs and Metabolites: Is There a Winner? 6. Electrospray Operational Parameters in ToF-MS 7. Maldi ToF-MS for Characterization of Synthetic Polymers in Aqueous Environment 8. The Potential of Ambient Desorption Ionization Methods Combined with High Resolution Mass Spectrometry for Pesticide Testing in Food 9. Application of GC-ToF-MS for Pesticide Residue Analysis in Grapes