Mosquito-borne Diseases Drug Development Pipeline Review, 2018

  • ID: 4557093
  • Report
  • Region: Global
  • 142 Pages
  • GBI Research
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FEATURED COMPANIES

  • 4SC AG
  • Bavarian Nordic A/S
  • DMG Deutsche Malaria GmbH
  • Hawaii Biotech Inc
  • Kymab Ltd
  • Osivax SAS
  • MORE

West Nile infection, Japanese encephalitis and yellow fever are all caused by flaviviruses, whereas malaria is caused by a parasite (Plasmodium). Symptoms of West Nile infection include a fever, headache, body aches, skin rash, and swollen lymph glands. There are 18 products in development for this indication.

Japanese encephalitis affects the membranes around the brain. Symptoms include fever, headache, muscle pain, diarrhea, seizures, muscle weakness and paralysis. There are 17 products in development for this indication.

Yellow fever is an acute systemic illness (hemorrhagic fever). Symptoms include irregular heartbeats, bleeding, vomiting, coma, delirium, fever, headache and muscle aches. There are 15 products in development for this indication.

Malaria is a life-threatening blood disease. Symptoms may include fever, chills, headache, sweats, fatigue, enlarged spleen, nausea and vomiting. There are 206 products in development for this indication.

Molecular targets acted on by products in development for mosquito-borne diseases include interferon receptors, toll-like receptors and pathogen proteins such as Plasmodium falciparum merozoite surface proteins. Companies operating in this pipeline space include Sanaria, Medigen and Ology Bioservices.

This report "Mosquito-borne Diseases Drug Development Pipeline Review, 2018"provides an overview of the pipeline landscape for mosquito-borne diseases and comprehensive information on the therapeutics under development and key players involved in therapeutic development for West Nile virus infections, Japanese encephalitis, yellow fever and malaria. It also features dormant and discontinued products.

Scope

  • Which companies are the most active within each pipeline?
  • Which pharmaceutical approaches are the most prominent at each stage of the pipeline and within each indication?
  • To what extent do universities and institutions play a role within this pipeline, compared to pharmaceutical companies?
  • What are the most important R&D milestones and data publications to have happened in this disease area?

Reasons to buy

  • Understand the overall pipeline, with an at-a-glance overview of all products in therapeutic development for each indication
  • Assess the products in development in granular detail, with an up-to-date overview of each individual pipeline program in each indication and a comprehensive picture of recent updates and milestones for each
  • Analyze the companies, institutions and universities currently operating in the pipeline and the products being fielded by each of these
  • Understand the composition of the pipeline in terms of molecule type, molecular target, mechanism of action and route of administration.
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Note: Product cover images may vary from those shown
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FEATURED COMPANIES

  • 4SC AG
  • Bavarian Nordic A/S
  • DMG Deutsche Malaria GmbH
  • Hawaii Biotech Inc
  • Kymab Ltd
  • Osivax SAS
  • MORE

1 Table of Contents

2 Introduction
2.1 Mosquito-borne Diseases Report Coverage
2.2 West Nile Virus Infections - Overview
2.3 Japanese Encephalitis - Overview
2.4 Yellow Fever - Overview
2.5 Malaria - Overview

3 Therapeutics Development
3.1 West Nile Virus Infections
3.2 Japanese Encephalitis
3.3 Yellow Fever
3.4 Malaria

4 Therapeutics Assessment
4.1 West Nile Virus Infections
4.2 Japanese Encephalitis
4.3 Yellow Fever
4.4 Malaria

5 Companies Involved in Therapeutics Development
5.1 West Nile Virus Infections
5.2 Japanese Encephalitis
5.3 Yellow Fever
5.4 Malaria

6 Dormant Projects
6.1 West Nile Virus Infections
6.2 Japanese Encephalitis
6.3 Yellow Fever
6.4 Malaria

7 Discontinued Products
7.1 Japanese Encephalitis
7.2 Malaria

8 Product Development Milestones
8.1 West Nile Virus Infections
8.2 Yellow Fever
8.3 Malaria

9 Appendix
9.1 Methodology
9.2 Coverage
9.3 Secondary Research
9.4 Primary Research
9.5 Expert Panel Validation

List of Tables
Table 1: Number of Products under Development for West Nile Virus Infections
Table 2: Number of Products under Development by Companies, West Nile Virus Infections
Table 3: Number of Products under Development by Universities/Institutes, West Nile Virus Infections
Table 4: Products under Development by Companies, West Nile Virus Infections
Table 5: Products under Development by Universities/Institutes, West Nile Virus Infections
Table 6: Number of Products under Development for Japanese Encephalitis
Table 7: Number of Products under Development by Companies, Japanese Encephalitis
Table 8: Number of Products under Development by Universities/Institutes, Japanese Encephalitis
Table 9: Products under Development by Companies, Japanese Encephalitis
Table 10: Products under Development by Universities/Institutes, Japanese Encephalitis
Table 11: Number of Products under Development for Yellow Fever
Table 12: Number of Products under Development by Companies, Yellow Fever
Table 13: Number of Products under Development by Universities/Institutes, Yellow Fever
Table 14: Products under Development by Companies, Yellow Fever
Table 15: Products under Development by Universities/Institutes, Yellow Fever
Table 16: Number of Products under Development for Malaria
Table 17: Number of Products under Development by Companies, Malaria
Table 18: Number of Products under Development by Universities/Institutes, Malaria
Table 19: Products under Development by Companies, Malaria
Table 20: Products under Development by Universities/Institutes, Malaria
Table 21: Number of Products by Stage and Target, West Nile Virus Infections
Table 22: Number of Products by Stage and Mechanism of Action, West Nile Virus Infections
Table 23: Number of Products by Stage and Route of Administration, West Nile Virus Infections
Table 24: Number of Products by Stage and Molecule Type, West Nile Virus Infections
Table 25: Number of Products by Stage and Target, Japanese Encephalitis
Table 26: Number of Products by Stage and Mechanism of Action, Japanese Encephalitis
Table 27: Number of Products by Stage and Route of Administration, Japanese Encephalitis
Table 28: Number of Products by Stage and Molecule Type, Japanese Encephalitis
Table 29: Number of Products by Stage and Target, Yellow Fever
Table 30: Number of Products by Stage and Mechanism of Action, Yellow Fever
Table 31: Number of Products by Stage and Route of Administration, Yellow Fever
Table 32: Number of Products by Stage and Molecule Type, Yellow Fever
Table 33: Number of Products by Stage and Target, Malaria
Table 34: Number of Products by Stage and Mechanism of Action, Malaria
Table 35: Number of Products by Stage and Route of Administration, Malaria
Table 36: Number of Products by Stage and Molecule Type, Malaria
Table 37: West Nile Virus Infections - Pipeline by CEL-SCI Corp
Table 38: West Nile Virus Infections - Pipeline by Ennaid Therapeutics LLC
Table 39: West Nile Virus Infections - Pipeline by Hawaii Biotech Inc
Table 40: West Nile Virus Infections - Pipeline by Hemispherx Biopharma Inc
Table 41: West Nile Virus Infections - Pipeline by Kineta Inc
Table 42: West Nile Virus Infections - Pipeline by Ology Bioservices Inc
Table 43: West Nile Virus Infections - Pipeline by Plex Pharmaceuticals Inc
Table 44: Japanese Encephalitis - Pipeline by Abivax SA
Table 45: Japanese Encephalitis - Pipeline by Adimmune Corp
Table 46: Japanese Encephalitis - Pipeline by Cadila Healthcare Ltd
Table 47: Japanese Encephalitis - Pipeline by Ennaid Therapeutics LLC
Table 48: Japanese Encephalitis - Pipeline by Indian Immunologicals Ltd
Table 49: Japanese Encephalitis - Pipeline by Kineta Inc
Table 50: Japanese Encephalitis - Pipeline by Livzon Pharmaceutical Group Inc
Table 51: Japanese Encephalitis - Pipeline by Panacea Biotec Ltd
Table 52: Japanese Encephalitis - Pipeline by Sinovac Biotech Ltd
Table 53: Yellow Fever - Pipeline by Bavarian Nordic A/S
Table 54: Yellow Fever - Pipeline by BioCryst Pharmaceuticals Inc
Table 55: Yellow Fever - Pipeline by Emergex Vaccines Ltd
Table 56: Yellow Fever - Pipeline by Ennaid Therapeutics LLC
Table 57: Yellow Fever - Pipeline by iBio Inc
Table 58: Yellow Fever - Pipeline by Ology Bioservices Inc
Table 59: Yellow Fever - Pipeline by Sihuan Pharmaceutical Holdings Group Ltd
Table 60: Yellow Fever - Pipeline by Valneva SE
Table 61: Malaria - Pipeline by 4SC AG
Table 62: Malaria - Pipeline by AbbVie Inc
Table 63: Malaria - Pipeline by Agilvax Inc
Table 64: Malaria - Pipeline by Akshaya Bio Inc
Table 65: Malaria - Pipeline by AlfaSigma SpA
Table 66: Malaria - Pipeline by Allergy Therapeutics Plc
Table 67: Malaria - Pipeline by Altimmune Inc
Table 68: Malaria - Pipeline by Artificial Cell Technologies Inc
Table 69: Malaria - Pipeline by AstraZeneca Plc
Table 70: Malaria - Pipeline by Bharat Biotech Ltd

List of Figures
Figure 1: Number of Products under Development for West Nile Virus Infections
Figure 2: Number of Products under Development by Companies, West Nile Virus Infections
Figure 3: Number of Products under Development by Universities/Institutes, West Nile Virus Infections
Figure 4: Number of Products under Development for Japanese Encephalitis
Figure 5: Number of Products under Development by Companies, Japanese Encephalitis
Figure 6: Number of Products under Development by Universities/Institutes, Japanese Encephalitis
Figure 7: Number of Products under Development for Yellow Fever
Figure 8: Number of Products under Development by Companies, Yellow Fever
Figure 9: Number of Products under Development by Universities/Institutes, Yellow Fever
Figure 10: Number of Products under Development for Malaria
Figure 11: Number of Products under Development by Companies, Malaria
Figure 12: Number of Products under Development by Universities/Institutes, Malaria
Figure 13: Number of Products by Targets, West Nile Virus Infections
Figure 14: Number of Products by Stage and Targets, West Nile Virus Infections
Figure 15: Number of Products by Mechanism of Actions, West Nile Virus Infections
Figure 16: Number of Products by Stage and Mechanism of Actions, West Nile Virus Infections
Figure 17: Number of Products by Routes of Administration, West Nile Virus Infections
Figure 18: Number of Products by Stage and Routes of Administration, West Nile Virus Infections
Figure 19: Number of Products by Molecule Types, West Nile Virus Infections
Figure 20: Number of Products by Stage and Molecule Types, West Nile Virus Infections
Figure 21: Number of Products by Routes of Administration, Japanese Encephalitis
Figure 22: Number of Products by Stage and Routes of Administration, Japanese Encephalitis
Figure 23: Number of Products by Molecule Types, Japanese Encephalitis
Figure 24: Number of Products by Stage and Molecule Types, Japanese Encephalitis
Figure 25: Number of Products by Targets, Yellow Fever
Figure 26: Number of Products by Stage and Targets, Yellow Fever
Figure 27: Number of Products by Mechanism of Actions, Yellow Fever
Figure 28: Number of Products by Stage and Mechanism of Actions, Yellow Fever
Figure 29: Number of Products by Routes of Administration, Yellow Fever
Figure 30: Number of Products by Stage and Routes of Administration, Yellow Fever
Figure 31: Number of Products by Molecule Types, Yellow Fever
Figure 32: Number of Products by Stage and Molecule Types, Yellow Fever
Figure 33: Number of Products by Targets, Malaria
Figure 34: Number of Products by Stage and Targets, Malaria
Figure 35: Number of Products by Top 10 Mechanism of Actions, Malaria
Figure 36: Number of Products by Stage and Mechanism of Actions, Malaria
Figure 37: Number of Products by Routes of Administration, Malaria
Figure 38: Number of Products by Stage and Routes of Administration, Malaria
Figure 39: Number of Products by Top 10 Molecule Types, Malaria
Figure 40: Number of Products by Stage and Top 10 Molecule Types, Malaria

Note: Product cover images may vary from those shown
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  • 4SC AG
  • AbbVie Inc
  • Abivax SA
  • Adimmune Corp
  • Agilvax Inc
  • Akshaya Bio Inc
  • AlfaSigma SpA
  • Allergy Therapeutics Plc
  • Altimmune Inc
  • Artificial Cell Technologies Inc
  • AstraZeneca Plc
  • Bavarian Nordic A/S
  • Bharat Biotech Ltd
  • BioCryst Pharmaceuticals Inc
  • Cadila Healthcare Ltd
  • Carna Biosciences Inc
  • Celgene Corp
  • CEL-SCI Corp
  • Cilian AG
  • Curevac AG
  • Daiichi Sankyo Co Ltd
  • DesignMedix Inc
  • DMG Deutsche Malaria GmbH
  • Eisai Co Ltd
  • Emergex Vaccines Ltd
  • Ennaid Therapeutics LLC
  • Fosun International Ltd
  • GenVec Inc
  • Genzyme Corp
  • GeoVax Labs Inc
  • GlaxoSmithKline Plc
  • Hager Biosciences LLC
  • Hawaii Biotech Inc
  • Hemispherx Biopharma Inc
  • iBio Inc
  • Ichor Medical Systems Inc
  • ID Pharma Co Ltd
  • Immunovaccine Inc
  • Indian Immunologicals Ltd
  • IPCA Laboratories Ltd
  • Kancera AB
  • Kineta Inc
  • Kymab Ltd
  • Lipocure Ltd
  • Livzon Pharmaceutical Group Inc
  • LondonPharma Ltd
  • Marinomed Biotech AG
  • Merck KGaA
  • Microbiotix Inc
  • Mitsubishi Tanabe Pharma Corp
  • Mymetics Corp
  • Nobelpharma Co Ltd
  • Novartis AG
  • Ology Bioservices Inc
  • Osivax SAS
  • Otsuka Holdings Co Ltd
  • Panacea Biotec Ltd
  • PaxVax Inc
  • Pfizer Inc
  • Plex Pharmaceuticals Inc
  • Protein Potential LLC
  • Rodos BioTarget GmbH
  • Sanaria Inc
  • Sanofi
  • SBI Pharmaceuticals Co Ltd
  • Sihuan Pharmaceutical Holdings Group Ltd
  • Sinovac Biotech Ltd
  • Takeda Pharmaceutical Co Ltd
  • Theravectys SA
  • Titan Pharmaceuticals Inc
  • Valneva SE
  • VLP Biotech Inc
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