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Results for tag: "78 Kda Glucose Regulated Protein"

78 kda Glucose Regulated Protein - Pipeline Review, H2 2019 - Product Thumbnail Image

78 kda Glucose Regulated Protein - Pipeline Review, H2 2019

  • Drug Pipelines
  • December 2019
  • 47 Pages
  • Global
From
78 kda Glucose Regulated Protein (Endoplasmic Reticulum Lumenal Ca Binding Protein Grp78 or Heat Shock 70 kDa Protein 5 or Immunoglobulin Heavy Chain Binding Protein or HSPA5) Drugs in Development by Therapy Areas and Indications, Stages, MoA, RoA, Molecule Type and Key Players - Product Thumbnail Image

78 kda Glucose Regulated Protein (Endoplasmic Reticulum Lumenal Ca Binding Protein Grp78 or Heat Shock 70 kDa Protein 5 or Immunoglobulin Heavy Chain Binding Protein or HSPA5) Drugs in Development by Therapy Areas and Indications, Stages, MoA, RoA, Molecule Type and Key Players

  • Report
  • May 2022
  • 36 Pages
  • Global
From
78 kda Glucose Regulated Protein (Endoplasmic Reticulum Lumenal Ca(2+) Binding Protein Grp78 or Heat Shock 70 kDa Protein 5 or Immunoglobulin Heavy Chain Binding Protein or HSPA5) - Drugs in Development, 2021 - Product Thumbnail Image

78 kda Glucose Regulated Protein (Endoplasmic Reticulum Lumenal Ca(2+) Binding Protein Grp78 or Heat Shock 70 kDa Protein 5 or Immunoglobulin Heavy Chain Binding Protein or HSPA5) - Drugs in Development, 2021

  • Report
  • April 2021
  • 30 Pages
  • Global
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78 kda Glucose Regulated Protein (Endoplasmic Reticulum Lumenal Ca(2+) Binding Protein Grp78 or Heat Shock 70 kDa Protein 5 or Immunoglobulin Heavy Chain Binding Protein or HSPA5) - Pipeline Review, H2 2018 - Product Thumbnail Image

78 kda Glucose Regulated Protein (Endoplasmic Reticulum Lumenal Ca(2+) Binding Protein Grp78 or Heat Shock 70 kDa Protein 5 or Immunoglobulin Heavy Chain Binding Protein or HSPA5) - Pipeline Review, H2 2018

  • Drug Pipelines
  • July 2018
  • 42 Pages
  • Global
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  • 4 Results (Page 1 of 1)
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The 78 kDa Glucose Regulated Protein (GRP78) is a protein that plays an important role in the regulation of glucose metabolism and is involved in the pathogenesis of several immune disorders. It is a key component of the unfolded protein response (UPR), a cellular stress response that is activated in response to various forms of cellular stress, including inflammation. GRP78 is also involved in the regulation of the immune system, and its expression is increased in several immune disorders, including rheumatoid arthritis, systemic lupus erythematosus, and multiple sclerosis. In the context of immune disorders drugs, GRP78 is being studied as a potential target for the development of novel therapeutics. Several companies are researching and developing GRP78-targeted drugs, including AbbVie, AstraZeneca, and Merck. Additionally, several biotechnology companies are developing GRP78-targeted antibodies, including Genentech, Regeneron, and Sanofi. Show Less Read more