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Acetaminophen is a widely used over-the-counter (OTC) drug used to treat pain and reduce fever. It is the active ingredient in many OTC pain relievers and cold medicines, and is also available as a generic drug. Acetaminophen is generally considered safe when taken as directed, but can cause serious liver damage if taken in large doses or with alcohol. The OTC acetaminophen market is highly competitive, with many different brands and formulations available. Acetaminophen is available in a variety of forms, including tablets, capsules, liquids, and suppositories. It is also available in combination with other drugs, such as ibuprofen and aspirin. Some of the major companies in the OTC acetaminophen market include Johnson & Johnson, Bayer, GlaxoSmithKline, Pfizer, and Novartis. These companies produce a variety of acetaminophen-based products, including Tylenol, Excedrin, and Advil. Show Less Read more