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Acetyl CoA Carboxylase (ACC) is an enzyme that catalyzes the carboxylation of acetyl-CoA to form malonyl-CoA. It is a key enzyme in fatty acid biosynthesis and is found in all organisms that synthesize fatty acids. ACC is a multi-domain enzyme composed of two distinct domains, a biotin carboxylase domain and a carboxyltransferase domain. The biotin carboxylase domain binds biotin and catalyzes the carboxylation of biotin, while the carboxyltransferase domain transfers the carboxyl group from biotin to acetyl-CoA.
ACC is a key enzyme in the fatty acid biosynthesis pathway and is essential for the production of fatty acids. It is also involved in the regulation of fatty acid synthesis, as it is the target of several hormones and other regulatory molecules. ACC is also involved in the regulation of glucose and lipid metabolism, as well as in the regulation of energy balance.
The ACC market is composed of companies that produce and sell ACC enzymes and related products. These companies include Sigma-Aldrich, Merck, Novozymes, Roche, and Abcam. Show Less Read more
