Results for tag: "Bropirimine"

Bropirimine is an oncology drug used to treat certain types of cancer. It is a small molecule inhibitor of the enzyme dihydroorotate dehydrogenase (DHODH), which is involved in the production of pyrimidine nucleotides. Bropirimine has been approved by the US Food and Drug Administration (FDA) for the treatment of advanced renal cell carcinoma (RCC) and advanced hepatocellular carcinoma (HCC). It is also being investigated for the treatment of other types of cancer, including non-small cell lung cancer (NSCLC), colorectal cancer (CRC), and melanoma. Bropirimine is available in both oral and intravenous formulations. It is typically used in combination with other drugs, such as immunotherapies, targeted therapies, and chemotherapy. The drug is typically administered in cycles, with each cycle lasting for a few weeks. The market for Bropirimine is growing, as it is becoming increasingly used in the treatment of various types of cancer. Companies in the market include Bristol-Myers Squibb, Merck, Pfizer, and AstraZeneca. Show Less Read more