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Carglumic acid is a drug used to treat endocrine and metabolic disorders. It is a synthetic form of N-carbamoyl-L-glutamate, an intermediate in the urea cycle. Carglumic acid is used to treat N-acetylglutamate synthase (NAGS) deficiency, an inherited disorder that can cause ammonia to accumulate in the blood. It is also used to treat hyperammonemia, a condition in which the body has too much ammonia in the blood. Carglumic acid works by helping the body break down ammonia and other nitrogen-containing compounds.
Carglumic acid is available in tablet and powder form. It is usually taken once or twice a day, depending on the condition being treated. Common side effects include nausea, vomiting, and diarrhea.
The carglumic acid market is a niche market, with few companies offering the drug. Companies in the market include Orphan Europe, Orphan Technologies, and Orphan Canada. Show Less Read more