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Cozaar (losartan) is a medication used to treat high blood pressure and reduce the risk of stroke in people with hypertension. It belongs to a class of drugs known as angiotensin II receptor blockers (ARBs). Cozaar works by blocking the action of a hormone called angiotensin II, which causes blood vessels to narrow and increases blood pressure. By blocking the action of this hormone, Cozaar helps to relax the blood vessels and reduce blood pressure. Cozaar is one of several cardiovascular drugs available on the market. Other drugs in this class include Diovan (valsartan), Avapro (irbesartan), and Benicar (olmesartan). These drugs are used to treat high blood pressure and reduce the risk of stroke in people with hypertension. They work by blocking the action of angiotensin II, which causes blood vessels to narrow and increases blood pressure. Some companies that produce cardiovascular drugs include Pfizer, Merck, Novartis, and Sanofi. These companies produce a variety of medications, including Cozaar, Diovan, Avapro, and Benicar. Show Less Read more