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DNA Minor Groove Binders (MGBs) are a class of small molecules used in molecular diagnostics to bind to the minor groove of double-stranded DNA. MGBs are used to detect and quantify DNA sequences, and can be used to detect mutations, single nucleotide polymorphisms (SNPs), and other genetic variations. MGBs are also used to detect and quantify gene expression levels, and to identify and quantify gene expression patterns. MGBs are used in a variety of molecular diagnostic applications, including cancer diagnostics, infectious disease diagnostics, and prenatal diagnostics. MGBs are used in a variety of molecular diagnostic assays, including PCR, real-time PCR, and DNA sequencing. MGBs are also used in a variety of other molecular diagnostic applications, such as DNA methylation analysis, gene expression profiling, and gene expression quantification. MGBs are used in a variety of molecular diagnostic assays, including PCR, real-time PCR, and DNA sequencing. Companies in the MGB market include Illumina, Thermo Fisher Scientific, Agilent Technologies, Bio-Rad Laboratories, and Qiagen. Show Less Read more