Results for tag: "Evolocumab"

Evolocumab is a monoclonal antibody used in the treatment of cardiovascular diseases. It is a PCSK9 inhibitor, which works by blocking the action of the PCSK9 protein, thus reducing the amount of low-density lipoprotein (LDL) cholesterol in the blood. This helps to reduce the risk of cardiovascular events such as heart attack and stroke. Evolocumab is administered as an injection, either subcutaneously or intravenously. Evolocumab is used in combination with other lipid-lowering therapies, such as statins, to reduce LDL cholesterol levels in patients with primary hyperlipidemia or mixed dyslipidemia. It is also used in patients with homozygous familial hypercholesterolemia, who are unable to achieve adequate LDL cholesterol levels with other lipid-lowering therapies. Evolocumab is marketed by several pharmaceutical companies, including Amgen, Sanofi, Regeneron, and Pfizer. It is also available as a generic drug in some countries. Show Less Read more