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Fibrates are a class of drugs used to treat cardiovascular diseases, such as high cholesterol and triglyceride levels. They work by increasing the activity of the enzyme lipoprotein lipase, which helps to break down fats in the blood. Fibrates are often used in combination with statins, another class of drugs used to lower cholesterol levels. Fibrates are generally well tolerated, but can cause side effects such as muscle pain, nausea, and abdominal pain.
Fibrates are available in both prescription and over-the-counter forms. Commonly prescribed fibrates include fenofibrate, gemfibrozil, and clofibrate. Over-the-counter fibrates include omega-3 fatty acids, which are found in fish oil supplements.
Several companies are involved in the fibrates market, including Pfizer, Merck, GlaxoSmithKline, Sanofi, and Novartis. Show Less Read more