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Results for tag: "Growth Differentiation Factor 8"

Growth/Differentiation Factor 8 - Pipeline Review, H2 2020 - Product Thumbnail Image

Growth/Differentiation Factor 8 - Pipeline Review, H2 2020

  • Drug Pipelines
  • October 2020
  • 78 Pages
  • Global
From
Growth Differentiation Factor 8 - Pipeline Review, H2 2019 - Product Thumbnail Image

Growth Differentiation Factor 8 - Pipeline Review, H2 2019

  • Drug Pipelines
  • December 2019
  • 81 Pages
  • Global
From
  • 3 Results (Page 1 of 1)
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Growth Differentiation Factor 8 (GDF8) is a member of the transforming growth factor-beta (TGF-β) superfamily of proteins. It is involved in the regulation of cell growth, differentiation, and apoptosis. GDF8 is a potential therapeutic target for endocrine and metabolic disorders, such as obesity, diabetes, and metabolic syndrome. It has been shown to regulate the expression of genes involved in glucose and lipid metabolism, as well as the production of hormones involved in energy balance. GDF8 has also been shown to be involved in the regulation of bone formation and remodeling, and may be a potential therapeutic target for osteoporosis. GDF8 is being studied as a potential therapeutic target for a variety of endocrine and metabolic disorders. Several companies are developing GDF8-based therapies, including Novartis, Merck, and Pfizer. Other companies, such as Amgen and Regeneron, are also researching GDF8-based therapies. Show Less Read more