Results for tag: "Heparanase"

Heparanase is an enzyme that plays a role in the development of cancer. It is involved in the degradation of heparan sulfate, a component of the extracellular matrix, which is important for the growth and metastasis of cancer cells. As a result, it has become a target for the development of oncology drugs. Inhibitors of heparanase have been developed to block the activity of the enzyme and prevent the growth and spread of cancer cells. These inhibitors have been studied in preclinical and clinical trials for the treatment of various types of cancer, including breast, lung, and ovarian cancer. In addition, heparanase has been studied as a biomarker for cancer diagnosis and prognosis. It has been found to be elevated in the serum of cancer patients, and its levels can be used to monitor the progression of the disease. The heparanase market is expected to grow in the coming years as more drugs targeting the enzyme are developed and approved. Companies such as Merck, Pfizer, and Novartis are actively involved in the development of heparanase inhibitors for the treatment of cancer. Other companies such as Amgen, AstraZeneca, and Bristol-Myers Squibb are also researching the potential of heparanase inhibitors in oncology. Show Less Read more