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Over the Counter (OTC) Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) are a class of medications used to reduce inflammation and pain. They are available without a prescription and are used to treat a variety of conditions, including headaches, muscle aches, arthritis, and menstrual cramps. NSAIDs work by blocking the production of certain chemicals in the body that cause inflammation and pain. Common OTC NSAIDs include ibuprofen, naproxen, and aspirin. NSAIDs are generally safe and effective when taken as directed. However, they can cause side effects, such as stomach upset, nausea, and dizziness. People with certain medical conditions, such as kidney or liver disease, should not take NSAIDs without consulting their doctor. Companies in the OTC NSAID market include Bayer, Pfizer, GlaxoSmithKline, Novartis, and Johnson & Johnson. Show Less Read more