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Panitumumab is a monoclonal antibody used to treat metastatic colorectal cancer. It is a type of targeted therapy, which works by blocking the action of a protein called epidermal growth factor receptor (EGFR). This protein is found on the surface of some cancer cells and helps them to grow and spread. By blocking the action of EGFR, panitumumab can help to slow down the growth of cancer cells. It is usually used in combination with other chemotherapy drugs.
Panitumumab is approved by the US Food and Drug Administration (FDA) for the treatment of metastatic colorectal cancer in patients who have not responded to other treatments. It is also approved in Europe and other countries.
Panitumumab is marketed by Amgen, Inc. in the United States and by Merck KGaA in Europe and other countries. Other companies involved in the market include Pfizer, Inc., Bristol-Myers Squibb Company, and Eli Lilly and Company. Show Less Read more