Results for tag: "Protease Inhibitors"

Protease inhibitors are a class of compounds that serve to inhibit the enzymatic activity of proteases, which are enzymes responsible for the breakdown of proteins into amino acids. These inhibitors find applications across various industries, including pharmaceuticals, where they are employed in the development of treatments for diseases characterized by excessive or undesirable proteolytic activity. They are particularly important in therapeutic areas such as oncology, infectious diseases, and inflammatory conditions, where they modulate the activity of specific proteases implicated in disease pathology. In the context of enzymes, protease inhibitors are often used as research tools to understand protease function or to extend the shelf life of proteins in various biotechnological applications. These inhibitors can be synthetic or derived from natural sources. They are designed to bind to the protease, thus preventing the cleavage of substrate proteins. In biochemistry and molecular biology, such inhibitors are crucial for preserving the integrity of proteins during extraction and purification processes. Several companies operate within the protease inhibitors market, providing various formulations and specificities of inhibitors. Prominent players in this sector include Sigma-Aldrich (part of Merck KGaA), Roche, Thermo Fisher Scientific, and Promega Corporation. These companies offer a wide range of protease inhibitor products to cater to the diverse needs of research, diagnostics, and therapeutic markets. Show Less Read more