Results for tag: "Selinexor"

Selinexor is an oncology drug used to treat certain types of cancer. It is a selective inhibitor of nuclear export (SINE) compound that works by blocking the export of tumor suppressor proteins from the nucleus of cancer cells. This leads to the accumulation of these proteins in the nucleus, which can then induce cell death. Selinexor is approved for the treatment of relapsed or refractory multiple myeloma in combination with dexamethasone, and is being studied in clinical trials for other types of cancer. Selinexor is marketed by Karyopharm Therapeutics, Inc., a biopharmaceutical company focused on the discovery and development of novel drugs targeting nuclear transport and related pathways. Other companies in the market include Celgene Corporation, which is developing selinexor in combination with other drugs for the treatment of multiple myeloma, and Novartis, which is studying selinexor in combination with other drugs for the treatment of solid tumors. Show Less Read more