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Selonsertib is a drug used to treat liver and kidney disorders. It is a selective inhibitor of the apoptosis signal-regulating kinase 1 (ASK1) enzyme, which is involved in the regulation of cell death and inflammation. Selonsertib is used to treat nonalcoholic steatohepatitis (NASH), a chronic liver disease, and primary biliary cholangitis (PBC), an autoimmune liver disease. It is also used to treat chronic kidney disease (CKD) caused by diabetes. Selonsertib is available in both oral and intravenous formulations.
Selonsertib is a relatively new drug, and is still in the early stages of development. It is being studied in clinical trials for its potential to treat a variety of liver and kidney disorders. The drug has shown promise in treating NASH and PBC, and is being studied for its potential to treat CKD.
Several companies are involved in the development and commercialization of Selonsertib. These include Gilead Sciences, Inc., Merck & Co., Inc., and AstraZeneca plc. Show Less Read more