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Results for tag: "Sitaxentan"

Endothelin Receptor Antagonist - Pipeline Insight, 2024 - Product Thumbnail Image

Endothelin Receptor Antagonist - Pipeline Insight, 2024

  • Clinical Trials
  • January 2024
  • 60 Pages
  • Global
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Sitaxentan is a type of cardiovascular drug used to treat pulmonary arterial hypertension (PAH). It is a selective endothelin receptor antagonist, meaning it works by blocking the action of endothelin, a substance in the body that can cause blood vessels to narrow. This narrowing can lead to high blood pressure in the lungs, which can cause shortness of breath, fatigue, and other symptoms. Sitaxentan is taken orally and is usually prescribed in combination with other medications. Sitaxentan is a relatively new drug, having been approved by the US Food and Drug Administration in 2009. It is used to treat PAH in adults, and is generally well-tolerated with few side effects. It is not recommended for use in children or pregnant women. The Sitaxentan market is a growing one, with many companies developing and marketing the drug. Some of these companies include Actelion Pharmaceuticals, GlaxoSmithKline, Pfizer, and United Therapeutics. Show Less Read more