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Subsys is a type of analgesic drug used to treat severe pain. It is a sublingual spray form of fentanyl, a powerful opioid analgesic. Subsys is designed to provide rapid relief of breakthrough pain in cancer patients who are already taking other opioid medications. It is also used to treat pain in patients who have not responded to other opioid medications. Subsys is a Schedule II controlled substance, meaning it has a high potential for abuse and addiction. Subsys is a relatively new type of analgesic drug, and is not widely used. It is typically prescribed to cancer patients who have not responded to other opioid medications, and is not recommended for use in non-cancer patients. Subsys is not recommended for long-term use, as it can lead to tolerance and dependence. Companies in the Subsys market include Insys Therapeutics, Inc., Mylan N.V., and Teva Pharmaceutical Industries Ltd. Show Less Read more