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Supercritical Fluid Chromatography (SFC) is a chromatographic technique used in the pharmaceutical industry to separate and analyze compounds. It is a form of liquid chromatography that uses a supercritical fluid as the mobile phase. This fluid is a combination of carbon dioxide and a modifier, such as methanol or ethanol. The supercritical fluid has properties between those of a gas and a liquid, allowing it to be used as a mobile phase for chromatography. SFC is used to separate and analyze compounds that are difficult to separate using traditional liquid chromatography. It is also used to purify compounds, as the supercritical fluid can dissolve impurities more easily than a liquid.
SFC is used in the pharmaceutical industry to analyze and purify active pharmaceutical ingredients (APIs) and drug products. It is also used to analyze the impurities in APIs and drug products, as well as to identify and quantify the components of complex mixtures.
Some companies in the Supercritical Fluid Chromatography market include Waters Corporation, Agilent Technologies, Shimadzu Corporation, Thermo Fisher Scientific, and PerkinElmer. Show Less Read more