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Genentech, Inc., a biotechnology company, engages in the research, development, manufacture, and marketing of biotechnology products for treating patients with serious or life-threatening diseases in the United States. It offers molecular entities and medicines in the areas of oncology, immunology, neuroscience, metabolism, and infectious diseases. The company was founded in 1976 and is headquartered in South San Francisco, California. Genentech operates as a subsidiary of Roche Holdings, Inc.