RNA Recognition, Vol 623

  • ID: 4745974
  • Book
  • 412 Pages
  • Elsevier Science and Technology
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RNA Recognition, Volume 623, the latest volume in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. This updated volume covers a variety of topics, including The Preparation of cooperative RNA recognition complexes for crystallographic structural studies, Methods for thermal denaturation studies of fluorogenic aptamers, Dynamic combinatorial chemistry as a rapid, fragment-based approach to RNA-targeted compound discovery, Using a click chemistry assay to identify natural product ligands for pre-microRNAs, Lessons from exploration of chemical and structural small molecule:RNA space, Using ligand-observed NMR to study RNA-small molecule interactions, and much more.

  • Provides the authority and expertise of leading contributors from an international board of authors
  • Presents the latest release in the Methods in Enzymology series
  • Includes the latest information on RNA Recognition
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1. Preparation of cooperative RNA recognition complexes for crystallographic structural studies Traci Tanaka Hall 2. Methods for thermal denaturation studies of fluorogenic aptamers Aaron Engelhart 3. Chapter title to be confirmed Matt Disney 4. Dynamic Combinatorial Chemistry as a rapid, fragment-based approach to RNA-targeted compound discovery Benjamin Miller 5. Using a Click Chemistry Assay to Identify Natural Product Ligands for pre-microRNAs Amanda Garner 6. Lessons from exploration of chemical and structural small molecule:RNA space Amanda E. Hargrove 7. Using ligand-observed NMR to study RNA-small molecule interactions Jay Schneekloth 8. structure-guided ligand design for RNA targets Thomas Hermann 9. Melamine scaffolds that induce RNA structure-function via a base triple interface Dennis Bong 10. Chapter title to be confirmed Robert T. Batey 11. determining RNA dynamic ensembles using NMR and computation Hashim M. Al-Hashimi 12. Insights into RNA recognition through tertiary structure homology modeling with Rosetta Rhiju Das 13. Monitoring co-transcriptional folding of riboswitches through helicase unwinding of fluorescently labeled RNA Adrian Ferre-d'Amare 14. lessons from riboswitch dynamics and recognition Aiming Ren 15. Identifying tertiary structures on long noncoding RNAs using chemical probing Anna Marie Pyle 16. Chapter title to be confirmed Dev Arya 17. The Use of Electrospray Ionization Mass Spectrometry to Examine RNA-Ligand Interactions Christine Chow 18. Lessons from viral RNA recognition Victoria D'Souza 19. Design of and synthesis of potent peptide ligands for RNA Gabriele Varani 20. Molecular recognition of HIV-1 RNAs with Branched Peptides Webster Santos 21. Sequence-specific recognition of structured RNA by triplex-forming peptide nucleic acids Eriks Rozners 22. Calculating the thermodynamic optimum for a ligand-sensing RNA Rhiju Das
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