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Pathophysiology of Ischemia Reperfusion Injury and Use of Fingolimod in Cardioprotection

  • ID: 4753595
  • Book
  • 140 Pages
  • Elsevier Science and Technology
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Pathophysiology of Ischemia-Reperfusion Injury and Use of Fingolimod in Cardioprotection is a deep examination into the mechanisms of myocardial ischemiareperfusion injury and role of fingolimod as a cardioprotective agent through its antioxidant, anti-apoptotic and anti-inflammatory effects. Dr. Ahmed explore the physiology and pathophysiology of myocardial metabolism under normal and ischemic conditions and focused on pharmacological cardioprotection. They provide a concise, yet rigorous discussion of Ischemia-Reperfusion Injury, Myocardial Ischemia during Circulatory Arrest, Myocardial Reperfusion, Myocardial Protection related to Ischemia-Reperfusion Injury and Role of Fingolimod in Cardioprotection.
Pathophysiology of Ischemia-Reperfusion Injury and Use of Fingolimod in Cardioprotection is ideal for researchers, cardiovascular scientists, and clinical pharmacologists to further work in this challenging area and apply this knowledge to clinical trials for cardioprotection.

- Provides detailed and critical analysis of the latest research in the field from molecular basis to potential clinical relevance- Examines the effect of fingolimod/sphingosine 1-phosphate in cardioprotection, pointing to future myocardial preventative strategies

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1. Ischemia-Reperfusion Injury 2. Myocardial Ischemia 3. Myocardial Reperfusion 4. Cardioprotection 5. Experimental models for Ischemia reperfusion Injury 6. Role of Fingolimod in Cardioprotection

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Ahmed, Naseer
Naseer Ahmed is enthusiastic clinician-scientist who accomplished his PhD (Cardiovascular Sciences) and Postdoctoral fellowship from University of Verona, Verona, Italy. He completed his MBBS degree from Riphah International University, Islamabad, Pakistan. His research interest includes Ischemia-Reperfusion injury, Atherosclerosis & thrombosis and Arrhythmias. He is active research member of Cardiovascular Research lab, Verona and Coordinator of Functional Foods/ Complementary therapies in Cardio-metabolic disorders.
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