Pathophysiology of Ischemia Reperfusion Injury and Use of Fingolimod in Cardioprotection explores the physiology and pathophysiology of myocardial metabolism under normal and ischemic conditions. It examines current advancements and limitations of treatment, as well as prevention tactics that can be used against myocardial ischemia-reperfusion injury, also providing insights into potential new therapies. This concise, yet rigorous, coverage outlines an innovative cardioprotection strategy with insights into the mechanisms of myocardial ischemia-reperfusion injury and the role of fingolimod as a cardioprotective due to its anti-oxidant, anti-apoptotic and anti-inflammatory pathways.
- Provides detailed and critical analysis of the latest research in the field, from molecular basis, to potential clinical relevance
- Examines the effect of fingolimod/sphingosine 1-phosphate in cardioprotection, pointing to future myocardial preventative strategies
- Presents full coverage of the mechanisms of ischemia reperfusion injury
Naseer Ahmed is enthusiastic clinician-scientist who accomplished his PhD (Cardiovascular Sciences) and Postdoctoral fellowship from University of Verona, Verona, Italy. He completed his MBBS degree from Riphah International University, Islamabad, Pakistan. His research interest includes Ischemia-Reperfusion injury, Atherosclerosis & thrombosis and Arrhythmias. He is active research member of Cardiovascular Research lab, Verona and Coordinator of Functional Foods/ Complementary therapies in Cardio-metabolic disorders.
Soban Sadiq completed his medical degree at the University of Health Sciences (UHS)-Pakistan. His Research passion led him to pursue MPhil degree in Pharmacology from UHS. To further his research methodology and techniques he then trained at the University of Liverpool-UK and was earned a PhD in Molecular and Clinical Pharmacology. He has vast experience teaching, conducting research and publishing papers in national and international journals. His research interest includes natural products, diabetes and insulin resistance.