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Studies in Natural Products Chemistry, Vol 64

  • ID: 4829336
  • Book
  • 510 Pages
  • Elsevier Science and Technology
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Studies in Natural Products Chemistry, Volume 64, covers the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques that have made it possible to rapidly isolate and determine the structures and biological activity of natural products. The book highlights these new and exciting opportunities in the field of new drug development to the pharmaceutical industry. As natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects, this book is an ideal resource on the material presented.
  • Focuses on the chemistry of bioactive natural products
  • Contains contributions by leading authorities in the field
  • Presents sources of new pharmacophores
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1. The C-19 Methyl Substituted Sarpagine-Macroline-Ajmaline Alkaloids: Diversity, Occurrence, Bioactivity, and Synthesis 2. Recent Progress in the Synthesis of Antimalarial Indoloquinoline Natural Products and Analogues 3. Anticancer Activity of Natural Coumarins for Biological Targets 4. Silymarin Compounds: Chemistry, Innovative Extraction Techniques and Synthesis 5. The Olive-Tree Leaves as a Source of High-Added Value Molecules: Oleuropein 6. Progress in Studies on Meroterpenoids 7. Effects of Dietary N-3 Polyunsaturated Fatty Acids on Cardiovascular Disease 8. Potential of Natural Bioactive C-glycosyl Flavones for Antidiabetic Properties 9. Natural Products Encompassing Anti Tuberculosis Activities 10. Physiological Effects of Carotenoids on Hyperglycemia and Associated Events 11. Pharmacophore Modeling and Virtual Screening for the Discovery of Biologically Active Natural Products 12. Formation of Three-Dimensional Polymer Structures through Radical and Ionic Reactions of Peroxychitosan 13. Bioactive Natural Products as Potent Inhibitors of Xanthine Oxidase 14. Organocatalyzed ?-Aminooxylation/Amination of Aldehydes and their Sequential Reactions: A Versatile Tool for the Synthesis of Bioactive Molecules 15. Bioactive Compounds of Streptomyces: Biosynthesis to Applications

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Atta-ur-Rahman, Professor Emeritus, International Center for Chemical and Biological Sciences (H. E. J. Research Institute of Chemistry and Dr. Panjwani Center for Molecular Medicine and Drug Research), University of Karachi, Pakistan, was the Pakistan Federal Minister for Science and Technology (2000-2002), Federal Minister of Education (2002), and Chairman of the Higher Education Commission with the status of a Federal Minister from 2002-2008. He is a Fellow of the Royal Society of London (FRS) and an UNESCO Science Laureate. He is a leading scientist with more than 930 publications in several fields of organic chemistry.
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