Physiological and Biotechnological Aspects of Extremophiles highlights research in this rapidly growing field. Expert authors from around the world provide the latest insights into the mechanisms these fascinating organisms use to survive. The vast majority of extremophiles are microbes, mainly archaea and bacteria, but some are eukaryotes. These microbes live under chemical and physical extremes that are usually lethal to cellular molecules, yet they manage to survive and thrive. They are a valuable source of industrially important enzymes and recent research has revealed novel mechanisms and biomolecular structures with a broad range of potential applications in biotechnology, biomining and bioremediation.
Aimed at research scientists, students, microbiologists and biotechnologists, this book is essential reading for scientists working with extremophiles and a recommended reference text for anyone interested in the microbiology of these organisms, bioprospecting, biomining, biofuels and extremozymes.
- Shows the implications of the physiological adaptations of microbes from extreme habitats that are largely contributed by their biomolecules in basic to applied research
- Provides in-depth knowledge of genomic plasticity and proteome of different extremophiles
- Gives detailed and comprehensive insights on the use of genetic engineering and genome editing in industrial applications
1. Overview of extremophiles 2. Culture dependent and independent approaches for accessing community structure of extremophiles 3. Physiology of thermophiles 4. Quorum sensing in extremophiles 5. Osmoadaptation strategies of extremophiles 6. Comparative study of genome organizations in extremophiles 7. Microbial community structure in saline environment 8. Secretome analysis of extremophiles 9. Cold adaptation in psychrophiles using transcriptome and metatranscriptome 10. Genome editing in extremophiles using CRISPR/Cas9 technology 11. Codon optimization of genes for optimum production of enzymes from extremophiles 12. Structure and application of antifreeze proteins of psychrophiles 13. Understanding the structural basis of adaptation in enzymes from extremophiles 14. Oxidative stress response in halophilies 15. Low temperature active enzymes from psychrotolerant bacteria 16. Role of fatty acids in cold adaptation of psychrophilic bacteria 17. Ecological significance and industrial application of extremophiles 18. Engineering redox-balanced ethanol production in the cellulolytic thermophiles 19. Hydrolases of extremophiles and their implication in the saccharification of agricultural biomass for value added products 20. Lytic polysaccharides monooxygenases of extremophiles 21. Exopolysaccharides of thermophiles: Molecular, structural and rheological properties 22. Degradation of petroleum hydrocarbons and treatment of refinery wastewater by halophilic bacterial 23. Application of halophilic and haloalkaliphilic sulfur-oxidizing bacteria
Dr. Salwan is presently working as Young Scientist under DST funded project at Chandigarh University as Principal Scientist. She has published more than twenty research papers in journals of international reputations. She has also published 6 book chapters and presented her research in international conferences. She has been awarded National post doc fellowship (Npdf- SERB) in 2015 and 2017. She has completed her PhD in Biological Sciences from AcSIR - Academy of Scientific & Innovative Research, New Delhi India. She is working on the exploration of extremophiles for industrial relevant enzymes and agricultural benefits.
Dr. Sharma's work focuses on molecular aspects of plant beneficial microbes. He has published several research papers in journals including International Journal of Biological macromolecules, Frontiers in Microbiology, European Journal of Plant Pathology, Current Microbiology, Pesticide Biochemistry and Physiology. He is a reviewer in journals of international reputation such as MDPI Pathogens, Molecular Biotechnology, Folia Microbiology, Physiological and Molecular Plant Pathology, Archive of Microbiology etc. Dr. Vivek Sharma did his PhD from CSIR-Institute of Himalyan Bioresource Technology, Palampur Himachal Pradesh, India. Dr. Sharma has qualified CSIR-UGC junior Research Fellowship and awarded DST Young Scientist award under Fast Track Scheme. Dr. Sharma was selected for ARO post doc fellowship at Israel in 2017-18. He is presently working as Assistant Professor in University Centre For Research and Development at Chandigarh University, Punjab. He is having research experience of more than 12 years in exploring molecular attributes of Trichoderma involved in different plant benefits.