- Provide a current and easily digestible resource on chromatin and epigenetics
- Addresses the role of chromatin in transcription regulation and chromatin abnormalities in disease
- Valuably covers the background of the field - the history of the nucleosome and the early days of chromatin research - enabling readers to understand how the field was born and what discoveries and technical advances have propelled it forward
Part I. Chromatin structure 1. Early history 2. Figuring out the nucleosome 3. Nucleosome positioning
Part 2. Chromatin function 4. Early studies 5. Chromatin remodeling 6. Chromatin modifications
The author has more than 30 years' experience in the fields of biochemistry, molecular biology and genetics, much of which has involved research involving Chromatin structure, function and genetics. He has been teaching this topic in intro graduate level courses since 1994, has participated in numerous conferences devoted to chromatin research, and has obtained grants and published articles involving research on chromatin structure and function.