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Bioprocess Controllers and Automation Systems Market By Type of Controllers, Scale of Operation, Types of Processes Controlled, Mode of Operation, Compatibility with Bioprocessing Systems, and Key Geographical Regions: Industry Trends and Global Forecasts, 2021-2030

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    Report

  • 237 Pages
  • September 2021
  • Region: Global
  • Roots Analysis
  • ID: 5510463

Overview

Over the past few decades, biopharmaceuticals have gained significant popularity owing to their therapeutic efficacy, favorable safety profiles and ability to treat a wide variety of disease indications, which are otherwise hard to treat. The success of these interventions has prompted the stakeholders to upgrade the conventional biologics manufacturing equipment. As a result, the domain has witnessed several technological advancements, including the adoption of controllers and automated systems. These systems not only ensure that the processes continue to run within precise limits but also make the necessary adjustments, while minimizing the risk of human errors and improving the product quality. Additionally, these controllers and automation systems have the potential to address a number of challenges associated with traditional bioprocessing systems and offer various additional benefits, such as lowering of production and labor cost (by 20-30%), optimizing the energy consumption (by 5-30%) and increasing the overall productivity (by 10-20%).


Given the various advantages of controllers and automated systems, biopharmaceutical developers and manufacturers are steadily adopting such solutions. Moreover, the recent surge in demand for vaccines amidst the ongoing COVID-19 pandemic has also prompted the biopharmaceutical companies to develop automation systems for producing drugs at a faster pace. In addition, several equipment manufacturers offering more user-friendly, controlled, and automated systems, have emerged. In fact, the field has been witnessing a lot of innovations, evident from the number of patents filed for the controllers and automation systems. These controllers and automated systems use process analytical technological tools that can be easily integrated in the bioprocessing unit to improve scalability. Stakeholders have also been focusing on making further improvements and have incorporated a variety of key features, including provisions for alerts/alarms, built-in system process control sensors, remote monitoring features, visual display, and advanced safety provisions. Owing to the rising interest of stakeholders towards technological advancement and adoption of these systems, we believe that the overall bioreactor controller and automation systems market is anticipated to witness substantial growth in the coming years.


Scope of the Report

The “Bioprocess Controllers and Automation Systems Market By Type of Controllers (Upstream/Downstream Controller System and Bioprocess Control Software), Scale of Operation (Preclinical/Clinical Operations and Commercial Operations), Mode of Operation (Batch, Fed-Batch and Perfusion), Compatibility with Bioprocessing Systems (Single-Use Systems, and Stainless Steel/Other Systems), and Key Geographical Regions (North America, Europe, Asia-Pacific and Rest of the World): Industry Trends and Global Forecasts, 2021-2030” report features an extensive study of the current landscape and the likely future potential of bioprocess controllers and automation systems, over the next decade. The study also features an in-depth analysis, highlighting the capabilities of various industry stakeholders engaged in this field.


In addition to other elements, the study includes:

  • A detailed assessment of the overall market landscape of bioprocess controller and automation systems (upstream controllers, downstream controller systems and bioprocess control software) based on a number of relevant parameters, such as scale of operation (lab, clinical and commercial), mode of operation (batch, fed-batch and perfusion), key features (scalability/ease to use, visual data display, remote accessibility, data processing capabilities, built-in system control sensors, expansive I/O compatibility and provisions for alarms/alerts), compatibility with the bioprocessing systems (stirred tank (glass), single use bioreactor, stirred tank (steel), fermenter, rocking motion, chromatography system, tangential flow filtration system), type of system(s) (single-use system and multi-use system) and type of processes controlled (cell cultivation, microbial fermentation, chromatography and filtration). In addition, it presents details of the companies developing bioprocess controller and automation systems, highlighting their year of establishment, company size, and geographical presence.
  • A detailed competitiveness analysis of upstream controllers, downstream controller systems and process control software, taking into consideration several relevant parameters, such as the product applicability (scale of operation, processes controlled, mode of operation and stage of bioprocess) and product strength (key features, and compatibility with system).
  • Tabulated profiles of the key players providing upstream controllers, downstream controller systems and process control software. Each profile includes an overview of the company, information on the financial performance (if available), product portfolio, recent developments, and an informed future outlook.
  • A contemporary market trend analysis, featuring a world map representation to highlight the regional distribution of players engaged in the development of upstream controllers, downstream controller systems and bioprocess control software, along with the information on type of products offered (upstream controllers, downstream controller systems and bioprocess control software). Further, the chapter also presents (a) a heat map representation of upstream controllers, based on compatibility with bioreactor systems, scale of operation and mode of operation, (b) a grid analysis of upstream controllers, based on scale of operation, compatibility with bioreactor systems and processes controlled (c) a grid analysis of downstream controller systems, based on scale of operation, type of systems and key features, (d) an analysis of downstream controller systems, based on mode of operation and application area (e) a grid analysis of bioprocess control software, based on scale of operation, key features and processes controlled and (f) an analysis of bioprocess control software, based on scale of operation and compatibility with bioprocessing systems.
  • An in-depth analysis of various patents that have been filed/granted for bioprocess controller and automation systems, till July 2021, highlighting key trends associated with these patents, across type of patents, publication year, application year, issuing authorities involved, type of organizations, emerging focus area, patent age, CPC symbols, leading patent assignees (in terms of number of patents granted/filed), patent characteristics and geography. It also includes a detailed patent benchmarking and an insightful valuation analysis.
  • A detailed brand positioning analysis of the key industry players (including upstream controller developers, downstream controller system developers, and bioprocess control software developers), highlighting the current perceptions regarding their proprietary products by taking into consideration several relevant aspects, such as experience of the manufacturer, number of products offered, product diversity, and number of patents published.

One of the key objectives of the report was to understand the primary growth drivers and estimate the future size of bioprocess controller and automation systems market. Based on multiple parameters, such as overall bioprocessing equipment market, and adoption rate of automation systems, we have provided an informed estimate of the evolution of the market for the period 2021-2030. Our year-wise projections of the current and future opportunity have further been segmented on the basis of [A] type of controllers (upstream controllers, downstream controller system and bioprocess control software), [B] scale of operation (preclinical/clinical operations and commercial operations), [C] mode of operation (batch, fed-batch and perfusion), [D] compatibility with bioprocessing systems (single-use systems, and stainless steel/other systems), and [E] key geographical regions (North America, Europe, Asia-Pacific and Rest of the World). In order to account for future uncertainties and to add robustness to our model, we have provided three forecast scenarios, namely conservative, base and optimistic scenarios, representing different tracks of the industry’s growth.


The opinions and insights presented in the report are backed by a deep understanding of key insights generated from both secondary and primary research. The information presented in this study was also influenced by discussions held with senior stakeholders in this industry. 


All actual figures have been sourced and analyzed from publicly available information forums and primary research discussions. Financial figures mentioned in this report are in USD, unless otherwise specified.


Key Questions Answered

  • Who are the leading players engaged in the development of bioprocess controller and automation systems?
  • What are the different application areas where bioprocess controller and automation systems can be used?
  • What are the key features of bioprocess controller and automation systems?
  • How has the intellectual property landscape of bioprocess controller and automation, evolved over the years?
  • What are the key trends within the bioprocess controllers and automation systems market?
  • How is the current and future opportunity likely to be distributed across key market segments?

Table of Contents

1. PREFACE
1.1. Overview
1.2. Scope of the Report
1.3. Key Questions Answered
1.4. Research Methodology
1.5. Chapter Outlines


2. EXECUTIVE SUMMARY
3. INTRODUCTION
3.1. Chapter Overview
3.2. Bioprocess Control
3.3. Building Block of Process Control
3.3.1. Components of Process Control Systems
3.3.1.1. Sensors
3.3.1.2. Actuators
3.3.1.3. Controllers
3.4. Purpose of Process Control
3.5. Bioprocess Automation
3.6. Advantages of Bioprocess Automation
3.7. Challenges Faced in Automated Control
3.7.1. Process Related Challenges to Automate
3.7.2. Compatibility and Infrastructure Challenges
3.7.3. Regulatory Challenges
3.7.4. IT Concerns and Data Integrity
3.8. Breakthrough in Bioprocess Control
3.8.1. Flexible and Automated Skids
3.8.2. Spectroscopy
3.8.3. Multivariate data Analytics
3.9. Future Perspective


4. MARKET LANDSCAPE: UPSTREAM CONTROLLERS
4.1. Chapter Overview
4.2. Upstream Controllers: Product Pipeline
4.2.1. Analysis by Scale of Operation
4.2.2. Analysis by Key Features
4.2.3. Analysis by Compatibility with Bioreactor System
4.2.4. Analysis by Mode of Operation
4.2.5. Analysis by Types of Processes Controlled
4.3. Upstream Controllers: Developer Landscape
4.3.1. Analysis by Year of Establishment
4.3.2. Analysis by Company Size
4.3.3. Analysis by Location of Headquarters
4.3.4. Leading Developers: Analysis by Number of Upstream Controllers


5. MARKET LANDSCAPE: DOWNSTREAM CONTROLLER SYSTEMS
5.1. Chapter Overview
5.2. Downstream Controller Systems: Product Pipeline
5.2.1. Analysis by Scale of Operation
5.2.2. Analysis by Key Features
5.2.3. Analysis by Types of Systems Involved
5.2.4. Analysis by Mode of Operation
5.2.5. Analysis by Application Area
5.3.  Downstream Controller Systems: Developer Landscape
5.3.1. Analysis by Year of Establishment
5.3.2. Analysis by Company Size
5.3.3. Analysis by Location of Headquarters
5.3.4. Leading Developers: Analysis by Number of Products


6. MARKET LANDSCAPE: BIOPROCESS CONTROL SOFTWARE
6.1. Chapter Overview
6.2. Bioprocess Control Software: Product Pipeline
6.2.1. Analysis by Stage of Bioprocess
6.2.2. Analysis by Scale of Operation
6.2.3. Analysis by Key Features
6.2.4. Analysis by Compatibility with Systems
6.2.5. Analysis by Types of Processes Controlled
6.3. Bioprocess Control Software: Developer Landscape
6.3.1. Analysis by Year of Establishment
6.3.2. Analysis of Company Size
6.3.3. Analysis by Location of Headquarters
6.3.4. Leading Developers: Analysis by Number of Bioprocess Control Software


7. PRODUCT COMPETITIVENESS ANALYSIS
7.1. Chapter Overview
7.2. Methodology
7.3. Assumptions/Key Parameters
7.4. Product Competitiveness Analysis: Upstream Controllers
7.5. Product Competitiveness Analysis: Downstream Controller Systems
7.6. Product Competitiveness Analysis: Bioprocess Controller Software


8. BIOPROCESS CONTROLLER AND AUTOMATION SYSTEM DEVELOPERS IN NORTH AMERICA: COMPANY PROFILES
8.1. Chapter Overview
8.2. Cytiva Lifesciences
8.2.1. Company Overview
8.2.2. Bioprocess Controller and Automation System Portfolio
8.2.3. Recent Developments and Future Outlook
8.3. Thermo Fisher Scientific
8.3.1. Company Overview
8.3.2. Bioprocess Controller and Automation System Portfolio
8.3.3. Recent Developments and Future Outlook
8.4. Sepragen
8.4.1. Company Overview
8.4.2. Bioprocess Controller and Automation System Portfolio
8.4.3. Recent Developments and Future Outlook
8.5. Repligen
8.5.1. Company Overview
8.5.2. Bioprocess Controller and Automation System Portfolio
8.5.3. Recent Developments and Future Outlook


9. BIOPROCESS CONTROLLER AND AUTOMATION SYSTEM DEVELOPERS IN EUROPE: COMPANY PROFILES
9.1. Chapter Overview
9.2. Applikon Biotechnology
9.2.1. Company Overview
9.2.2. Bioprocess Controller and Automation System Portfolio
9.2.3. Recent Developments and Future Outlook
9.3. Sartorius
9.3.1. Company Overview
9.3.2. Bioprocess Controller and Automation System Portfolio
9.3.3. Recent Developments and Future Outlook
9.4. Solaris Biotech
9.4.1. Company Overview
9.4.2. Bioprocess Controller and Automation System Portfolio
9.4.3. Recent Developments and Future Outlook
9.5. Sysbiotech
9.5.1. Company Overview
9.5.2. Bioprocess Controller and Automation System Portfolio
9.5.3. Recent Developments and Future Outlook


10. MARKET TREND ANALYSIS
10.1. Chapter Overview
10.2. World Map Representation: Analysis of Players by Location of Headquarters and Type of Product(s) Offered
10.3. Market Trend Analysis: Upstream Controllers
10.3.1. Heat Map Representation: Analysis by Scale of Operation, Compatibility with Bioreactor Systems and Operating Mode
10.3.2. Grid Analysis: Analysis by Scale of Operation, Compatibility with Bioreactor Systems and Types of Processes Controlled
10.4. Market Trend Analysis: Downstream Controller Systems
10.4.1. Grid Analysis: Analysis by Scale of Operation, Type of System(s) and Key Features
10.4.2. Analysis by Operation Mode and Application Area
10.5. Market Trend Analysis: Bioprocess Control Software
10.5.1. Grid Analysis: Analysis by Scale of Operation, Key Features and Types of Processes Controlled
10.5.2. Analysis by Scale of operation and Compatibility with Systems


11. PATENT ANALYSIS
11.1. Chapter Overview
11.2. Scope and Methodology
11.3. Bioprocess Controller and Automations Systems: Patent Analysis
11.3.1. Analysis by Publication Year
11.3.2. Analysis by Application Year
11.3.3. Analysis by Patent Office
11.3.4. Analysis by Geographical Location
11.3.5. Analysis by CPC Symbols
11.3.6. Emerging Focus Area
11.3.7. Analysis by Type of Organization
11.3.8. Leading Players: Analysis by Number of Patents
11.4. Patent Benchmarking Analysis
11.4.1. Analysis by Patent Characteristics
11.5. Bioprocess Controller and Automations Systems: Patent Valuation Analysis
11.6. Leading Patents by Number of Citations


12. BRAND POSITIONING ANALYSIS
12.1. Chapter Overview
12.2 Methodology
12.3. Key Parameters
12.4. Brand Positioning Matrix of Upstream Controller Developers
12.4.1. Brand Positioning Matrix: Applikon Biotechnology
12.4.2. Brand Positioning Matrix: Eppendorf
12.4.3. Brand Positioning Matrix: Thermo Fisher Scientific
12.4.4. Brand Positioning Matrix: ILS Automation
12.4.5. Brand Positioning Matrix: Pierre Guerin
12.5. Brand Positioning Matrix of Downstream Controller System Developers
12.5.1. Brand Positioning Matrix: Cytiva Lifesciences
12.5.2. Brand Positioning Matrix: Sepragen
12.5.3. Brand Positioning Matrix: Merck Millipore
12.5.4. Brand Positioning Matrix: Sartorius Stedim Biotech
12.5.5. Brand Positioning Matrix: Repligen
12.5.6. Brand Positioning Matrix: Agilitech
12.6. Brand Positioning Matrix of Bioprocess Controller Software Developers
12.6.1. Brand Positioning Matrix: Applikon Biotechnology
12.6.2. Brand Positioning Matrix: Pierre Guerin
12.6.3. Brand Positioning Matrix: Thermo Fisher Scientific
12.6.4. Brand Positioning Matrix: Merck Millipore
12.6.5. Brand Positioning Matrix: Sartorius Stedim Biotech
12.6.6. Brand Positioning Matrix: Cytiva Lifesciences
12.6.7. Brand Positioning Matrix: Bionet Engineering


13. MARKET FORECAST AND OPPORTUNITY ANALYSIS
13.1. Chapter Overview
13.2. Forecast Methodology and Key Assumptions
13.3. Overall Bioprocess Controller and Automation Market, 2021-2030
13.4. Bioprocess Controller and Automation Market, 2021-2030: Distribution by Type of Controller
13.4.1. Bioprocess Controller and Automation Market for Upstream/Downstream Controller Systems, 2021-2030
13.4.2. Bioprocess Controller and Automation Market for Bioprocess Control Software, 2021-2030
13.5. Bioprocess Controller and Automation Market, 2021-2030: Distribution by Scale of Operation
13.5.1. Bioprocess Controller and Automation Market for Preclinical/Clinical Operations, 2021-2030
13.5.2. Bioprocess Controller and Automation Market for Commercial Operations, 2021-2030
13.6. Bioprocess Controller and Automation Market, 2021-2030: Distribution by Mode of Operation
13.6.1. Bioprocess Controller and Automation Market for Batch/Fed-batch Manufacturing, 2021-2030
13.6.2. Bioprocess Controller and Automation Market for Perfusion Manufacturing, 2021-2030
13.7. Bioprocess Controller and Automation Market, 2021-2030: Distribution by Type of Systems
13.7.1. Bioprocess Controller and Automation Market for Single-use Systems, 2021-2030
13.7.2. Bioprocess Controller and Automation Market for Stainless Steel/Other Systems, 2021-2030
13.8. Bioprocess Controller and Automation Market, 2021-2030: Distribution by Key Geographical Regions
13.8.1. Bioprocess Controller and Automation Market in North America, 2021-2030
13.8.2. Bioprocess Controller and Automation Market in Europe, 2021-2030
13.8.3. Bioprocess Controller and Automation Market in Asia-Pacific and Rest of the World, 2021-2030


14. CONCLUSION
14.1. Chapter Overview


15. EXECUTIVE INSIGHTS16. APPENDIX 1: TABULATED DATA17. APPENDIX 2: LIST OF COMPANIES AND ORGANIZATIONS

Companies Mentioned

  • Agilitech
  • Amgen
  • Andrew Alliance (acquired by Waters)
  • Applikon Biotechnology (acquired by Getinge)
  • ARTeSYN Biosolutions (acquired by Repligen)
  • Automated Control Concepts (ACC)
  • Bioengineering
  • BIONET
  • Bioreactors.net
  • BlueSens gas sensor
  • Clorox
  • CSL
  • Curexsys
  • Cytiva (acquired by Danaher)
  • DISTek
  • Duke University
  • Eppendorf
  • Flotek
  • Flownamics
  • General Electric (GE)
  • Getinge
  • GoSilico (acquired by Cytiva)
  • Harvard Business School
  • ILS Automation
  • INFORS HT
  • Inscripta
  • J. Craig Venter Institute (JCVI)
  • LAMBDA Laboratory Instruments
  • Lonza
  • Massachusetts Institute of Technology (MIT)
  • Medtronic
  • Merck Millipore
  • Novasep
  • Pall (acquired by Danaher)
  • Parker Hannifin
  • PendoTECH
  • Pierre Guérin
  • Plus Therapeutics (formerly Cytori Therapeutics)
  • Princeton University
  • Procter & Gamble (P&G)
  • Propel Labs
  • Repligen
  • Roche
  • Rockwell Automation
  • Sartorius Stedim Biotech
  • Securecell
  • Sepragen
  • Solaris Biotechnology
  • Solida Biotech
  • SYSBIOTECH
  • Terumo Blood and Cell Technologies 
  • Thermo Fisher Scientific
  • University of California
  • University of Maryland 
  • University of Missouri
  • Vanderbilt University
  • VERDOT Ips²
  • WaterSep BioSeparations (acquired by Sartorius)
  • Xyleco

Methodology

 

 

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