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Frontiers in Natural Product Chemistry (Volume 9)

  • Book

  • March 2022
  • Bentham Science Publishers Ltd
  • ID: 5574861
Frontiers in Natural Product Chemistry is a book series devoted to publishing monographs that highlight important advances in natural product chemistry. The series covers all aspects of research in the chemistry and biochemistry of naturally occurring compounds, including research on natural substances derived from plants, microbes, and animals. Reviews of structure elucidation, biological activity, organic and experimental synthesis of natural products as well as developments of new methods are also included in the series.

Volume nine of the series features a variety of natural products and sources
  • Propolis and its key chemical constituents: a promising natural product in therapeutic applications
  • Investigation of the effects of using omega-3 fatty acids on egg quality in functional egg production 
  • Quercetin, a flavonoid with remarkable anticancer activity 
  • Swertiamarin for the treatment of metabolic syndrome
  • Overview of traditional uses, phytochemistry, and pharmacology of Peganum harmala l. 
  • Investigation of measurement methods of antioxidant activity and involved mechanisms
  • Recent progress on natural and synthetic flavanone and its derivatives
  • Role of virgin coconut oil as a multiple health-promoting function oil

Table of Contents

 Chapter 1 Propolis And Its Key Chemical Constituents: A Promising Natural Product In Therapeutic Applications 
  •  Introduction 
  •  Natural Products 
  •  Propolis
  •  Chemical Composition and Medicinal Properties of Propolis Pinocembrin 
  •  Polyphenols and Flavonoids from Propolis and Therapeutic Potential   
  •  Caffeic Acid Phenethyl Ester (CAPE)  
  •  Conclusion 
  •  Consent for Publication 
  •  Conflict of Interest   
  •  Acknowledgements 
  •  References 

  Chapter 2 Investigation Of The Effects Of Using Omega-Fatty Acids On Egg Quality In Functional Egg Production
  • Introduction 
  •  Health Effects Of Omega- Fatty Acids 
  •  Egg as a Functional Food  
  •  Conclusion 
  •  Consent for Publication 
  •  Conflict of Interest   
  •  Acknowledgements
  •  References  

  Chapter 3 Quercetin, A Flavonoid With Remarkable Anticancer Activity 
  •  Introduction 
  •  Anticancer Effects Of QCT 
  •  Breast Cancer 
  •  Liver Cancer  
  •  Gastric Cancer 
  •  Lung Cancer   
  •  Glioma  
  •  Glioblastoma 
  •  Colon Cancer 
  •  Ovarian Cancer   
  •  Prostate Cancer  
  •  Cervical Cancer   
  •  Melanoma
  •  Oral Cancer   
  •  Uterine Leiomyoma
  •  Retinoblastoma   
  •  Chronic Myeloid Leukemia    
  •  Conclusions    
  •  Consent for Publication  
  •  Conflict of Interest   
  •  Acknowledgements  
  •  List of Abbreviations   
  •  References  

 Chapter 4 Swertiamarin For The Treatment Of Metabolic Syndrome  
  •  Introduction 
  •  Sources Of Swertiamarin   
  •  Chemistry, Biosynthesis And Derivatives Of Swertiamarin  
  •  Pathophysiology Of Metabolic Syndrome 
  •  Protective Effects Of Swertiamarin In Metabolic Disorder 
  •  Cardioprotective Effects Of Swertiamarin  
  •  Hypolipidemic And Anti-Atherogenic Effects Of Swertiamarin  
  •  Antioxidant Effects Swertiamarin 
  •  Anti-Inflammatory Effects Of Swertiamarin 
  •  Antihypertensive Effects Of Swertiamarin   
  •  Antidiabetic Effects Of Swertiamarin 
  •  Antiobesity Effects Of Swertiamarin 
  •  Concluding Remarks   
  •  Consent for Publication 
  •  Conflict of Interest   
  •  Acknowledgement   
  •  References 

  Chapter 5 Overview Of Traditional Uses, Phytochemistry And Pharmacology Of Peganum Harmala 
  •  Introduction 
  •  Botanical Classification    
  •  Botanical Description 
  •  Morphology   
  •  Distribution   
  •  Historical and Modern Cultivation    
  •  Phytochemistry    
  •  Dietary Composition 
  •  Medicinal Values and Traditional Uses 
  •  Pharmacology   
  •  Biosynthesis of Quinazoline   
  •  Green Synthesis of Metal Nanoparticles  
  •  Metabolism and Pharmacokinetics of Key Secondary Metabolites   
  •  Toxicology 
  •  Drug Interaction   
  •  Future Prospective   
  •  Conclusion  
  •  List of Abbreviations  
  •  Consent for Publication 
  •  Conflict of Interest   
  •  Acknowledgements 
  •  References  

 Chapter  6 Investigation Of Measurement Methods Of Antioxidant Activity And Involved Mechanisms  
  •  A Brief About Oxidation Reactions 
  •  Sample Preparation and Antioxidants Extraction 
  •  Plant Foods 
  •  Beverages  
  •  Oils   
  •  Increasing the Efficiency of Antioxidants Extraction 
  •  Main Chemical Reactions of Antioxidants 
  •  Single Electron Transfer (SET) and Hydrogen Atom Transfer (HAT)  
  •  Methods Using HAT Mechanism 
  •  Methods Using SET Mechanism  Methods
  •  Using HAT and SET Mechanisms Reactions  
  •  Principal Mechanisms Applied by Antioxidant Compounds    
  •  Factors Affecting Antioxidant Mechanisms And Capacity    
  •  Type of Bioactive Compounds   
  •  Ascorbic Acid
  •  Phenolic Compounds    
  •  Carotenoids   
  •  Minerals    
  •  Vitamin E (α-tocopherol)  
  •  Other Compounds  
  •  Processing Methods
  •  Milling   
  •  Blanching  
  •  Drying   
  •  Cooking
  •  Effect of Cooking Methods on Radical Scavenging Activity (RSA)    
  •  Effect of Cooking Methods on Total Phenolic Contents (TPC) 
  •  Effect of Cooking Methods on Ascorbic Acid Content (ASA)  
  •  Freezing 
  •  Ascorbic Acid Content  
  •  Anthocyanins Content   
  •  Acidity and pH 
  •  Some Other Methods 
  •  Solvents, Separated Fractions And Interferences Effects  
  •  Meddling Compounds  
  •  Practical Methods For Assessing Antioxidants In Laboratory    
  •  Determination of Total Phenolic Contents  Determination of Flavonoids Content    
  •  Determination of Flavonols Content  Determination of Ascorbic Acid Content   
  •  Determination of Vitamin E Contents   
  •  Determination of Carotenoids Content   
  •  Determination of Peroxide Value (PV)   
  •  Calibration of Fe (III):   
  •  Ferric Reducing Ability of Plasma Method (FRAP)  Advantages/Disadvantages 
  •  Trolox Equivalent Antioxidant Capacity Method (TEAC)  DPPH Approach   
  •  Oxygen Radical Absorbance Capacity Assay (ORAC Method)   
  •  ORAC Advantages / Disadvantages  Total Radical Trapping Antioxidant Parameter Method (TRAP)   
  •  TRAP Method Advantages / Disadvantages 
  •  Copper Reduction Method  Copper Reduction Method Advantages/Disadvantages  
  •  Total Oxidant Scavenging Capacity Method (TOSC)    
  •  Advantages / Disadvantages of TOSC   
  •  Conjugated Dienes TEST   
  •  Lipoxygenase Activity Inhibition Assay   
  •  Chemiluminescence (CL) Method   
  •  β-carotene Bleaching Assay    
  •  β-carotene Bleaching Inhibition   
  •  Deoxyribose Method 
  •  Fenton Reaction Mechanism   
  •  Tocopheroxyl Radical Attenuating Ability Method (TRAA)   
  •  Rancimat Method 
  •  Metals Chelating Method   
  •  Reducing Power Assay  Ferric Thiocyanate Method (FTC)   
  •  TBARS Method   
  •  Short TBARS and  Long TBARS  DMPD (N, N-Dimethyl-P-phenylenediamine) Method
  •  Scavenging Activity of Superoxide Anion 
  •  Nitric Oxide Radicals Trapping Method 
  •  HOCl Radicals Scavenging Method 
  •  Conclusion 
  •  Consent for Publication 
  •  Conflict of Interest  
  •  Acknowledgements 
  •  References  

 Chapter 7 Recent Progress On Natural And Synthetic Flavanone And Its Derivatives 
  •  Introduction  
  •  Synthetic Methods of Flavanones 
  •  Asymmetric Hydrogenation of Chromones 
  •  C-C Bond Formation
  •  Intramolecular Conjugation Addition to Chromones 
  •  β-Arylation of Chromanones  
  •  C-O Bond Formation    
  •  Cross Aldol Condensation Reaction (Claisen-Schmidt Condensation Reaction) of Aromatic Aldehyde  with ′-hydroxy acetophenone followed by Cyclization Reaction   
  •  Intermolecular Oxa-Michael addition of -hydroxy chalcones