Design Strategies to Avoid Drug Resistance, Volume 668 in the Methods in Enzymology serial, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of topics, including Machine learning in predicting the molecular mechanisms of drug resistance, TP53 mutations as molecular drivers in metastatic cancers, Avoiding antibiotic resistance in DHFR, Mutational fitness landscape and resistance, Avoiding Resistance in antivirals, Molecular mechanisms of antiviral resistance, and more.
Table of Contents
1. Machine learning in predicting the molecular mechanisms of drug resistanceCelia Schiffer
2. TP53 mutations as molecular drivers in metastatic cancers
Daruka Mahadevan
3. Avoiding antibiotic resistance in DHFR
Dennis Wright
4. Mutational fitness landscape and resistance
Dan Bolon
5. Avoiding Resistance in antivirals
Daria Hazuda
6. Molecular mechanisms of antiviral resistance
Pricilla Yang
