Ionizing Radiation and the Immune Response, Part B, Volume 378 reviews the latest knowledge on the immune response induced by ionizing radiations. Specific chapters in this new release include NK functions in radio-induced immune response, TRT and immune response, Radio-induced immune response and lipid metabolism, Effect of protons and heavy ions on immune response, Effect of flash therapy and mini beam on immune response, Radio-induced lymphopenia, CT to potentiate radio-induced immune response, Impact of RT on healthy tissues (inflammation), Radio-induced macrophagic response, To use nanoparticles and ionizing radiations to modulate immune response: opinion of the chemist, biologist and clinician, and much more.
Other sections cover the Role of Dendritic cells in radiation-induced immune response, the Relationship between the tumor microenvironment and the efficacy of the radiotherapy/immunotherapy combination, and Biomarkers of radiation induced response to optimize radio-immunotherapy combination.
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Table of Contents
PrefaceLorenzo Galluzzi and Celine Mirjolet
1. Radio-induced lymphopenia in the era of anti-cancer immunotherapy: A clinical review
Fran?ois de Kermenguy, Lydia Meziani, Michele Mondini, C?line Cl?menson, Daphn? Morel, Eric Deutsch and Charlotte Robert
2. Radiotherapy as a means to unlock NK cell immune response in solid tumors
Baude J?r?my, Limagne Emeric, Ladjohounlou Riad and Mirjolet C?line
3. The role of dendritic cells in radiation-induced immune responses
Aanchal Preet Kaur, Alejandro Alice, Marka R. Crittenden and Michael J. Gough
4. Immunomodulatory effects of targeted radionuclide therapy
Julie Constanzo, Yasmine Bouden, Lisa Godry, Pierre-Olivier Kotzky, Emmanuel Deshayes and J.-P. Pouget
5. Opportunities and challenges of low-dose radiation to enable immunotherapy efficacy
Katiuska Passelli, David Rep?raz and Fernanda Herrera
6. Radiation therapy-activated nanoparticle & immunotherapy: The next milestone in oncology?
S?bastien Penninckx, Juliette Thariat and C?line Mirjolet
7. Relationship between the tumor microenvironment and the efficacy of the combination of radiotherapy and immunotherapy
Chang Su, Jonathon E. Himes and David G. Kirsch
8. Recent advances in targeting myeloid-derived suppressor cells and their applications to radiotherapy
Zi-Zhan Li, Jing-Yu He, Qiuji Wu, Bing Liu and Lin-Lin Bu
