Heavy Metal Toxicity and Neurodegeneration delves into the intricate relationship between heavy metals and neurodegenerative diseases. It synthesizes and presents the latest research findings, shedding light on the mechanisms by which heavy metals cause neuronal damage and contribute to disease progression. By integrating various perspectives and collating diverse studies, this book serves as an invaluable resource for those seeking to understand the profound impact of heavy metals on neurological health. In addition to detailing the mechanisms involved, the book highlights the importance of early detection and preventive measures.
It caters to researchers, clinicians, policymakers, and students, offering a comprehensive and accessible overview that bridges the gap between theory and practical application. This scholarly work is poised to inform and guide future research and policy decisions in the field of neurodegenerative disease.
It caters to researchers, clinicians, policymakers, and students, offering a comprehensive and accessible overview that bridges the gap between theory and practical application. This scholarly work is poised to inform and guide future research and policy decisions in the field of neurodegenerative disease.
Table of Contents
1. Biological Pathways of Heavy Metal Toxicity2. Mechanisms of Neurodegeneration Induced by Heavy Metals
3. Lead Toxicity and Its Impact on Cognitive Function
4. Mercury Poisoning: Effects on the Central Nervous System
5. Arsenic Exposure and Neurotoxic Effects
6. Cadmium and Its Role in Neurodegenerative Diseases
7. Chromium Toxicity: Neurological Implications
8. Interactions Between Heavy Metals and Neuroinflammatory Processes
9. Oxidative Stress and Heavy Metal-Induced Neuronal Damage
10. Genetic Susceptibility to Heavy Metal Toxicity
11. The Role of Glutathione in Heavy Metal Detoxification
12. Heavy Metals and Alzheimer's Disease: A Review
13. Parkinson's Disease and Heavy Metal Exposure
14. Multiple Sclerosis: The Impact of Heavy Metals
15. Heavy Metals and Amyotrophic Lateral Sclerosis (ALS)
16. Neurodevelopmental Disorders Linked to Heavy Metal Exposure
17. Childhood Exposure to Heavy Metals and Long-Term Neurodevelopmental Effects
18. Environmental Sources of Heavy Metals and Their Health Impacts
19. Biomarkers for Assessing Heavy Metal Toxicity
20. Diagnostic Techniques for Heavy Metal-Induced Neurotoxicity
21. Prevention and Mitigation Strategies for Heavy Metal Exposure
22. Therapeutic Approaches for Heavy Metal Detoxification
23. Dietary Interventions for Reducing Heavy Metal Toxicity
24. Pharmacological Treatments for Neurodegeneration Due to Heavy Metals
25. Role of Chelation Therapy in Heavy Metal Detoxification
26. Impact of Heavy Metals on Neuroplasticity
27. Heavy Metal Toxicity and Psychiatric Disorders
28. Epidemiological Studies on Heavy Metal Exposure and Neurodegeneration
29. Regulatory Standards and Guidelines for Heavy Metal Exposure
Authors
Prasann Kumar Assistant Professor, Department of Agronomy, School of Agricultural (ICAR-Accredited), Lovely Professional University, Punjab, India. Dr. Prasann Kumar, assistant professor cum research intensive faculty in theDepartment of Agronomy, School of Agricultural (ICAR-Accredited), Lovely
Professional University, Punjab, specializes in stress physiology, plant tissue culture,
physiology of plant?microbe/pathogen interaction, and biodiversity management.
Dr. Kumar has completed the International Agricultural Rural Development
Programme from Cornell University, Ithaca, New York, United States. He has
received a doctorate from Banaras Hindu University, Varanasi. He also has
authored 40 books published by national and international publishers, which find
a place in national as well as various Overseas Institutions' libraries. He has
guided 19 MSc students for their thesis. Neha Gogia Post-Doctoral Associate, Yale University, Connecticut, USA. Dr. Gogia is a Post-Doctoral Associate at Yale. Having completed her PhD degree at the University of Dayton, and Cornell University's International Agriculture and Rural Development Program (IARD) she was awarded the Gerald L. Willis Award of Excellence for Outstanding Teaching in 2019. Her current work focuses on understanding cellular and molecular mechanisms underlying polyglutamine diseases, namely the identification and validation of genetic modifiers which can serve as potential therapeutic targets and can ameliorate the onset or progression of neurodegenerative diseases.