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U.S. Next-generation Sequencing Library Preparation Market Size, Share & Trends Analysis Report By Sequencing Type (Targeted Genome Sequencing, Whole Genome Sequencing), By Product, By Application, By End Use, And Segment Forecasts, 2025 - 2033

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    Report

  • 100 Pages
  • July 2025
  • Region: United States
  • Grand View Research
  • ID: 6154752
Description Jump to:
The U.S. next-generation sequencing library preparation market size was estimated at USD 652.2 million in 2024 and is projected to reach USD 1.96 billion by 2033, growing at a CAGR of 13.09% from 2025 to 2033. Rapid advancements in sequencing technologies and bioinformatics have facilitated the detection of DNA variations.

Additionally, the broad adoption of Next-Generation Sequencing (NGS) and Whole-Genome Sequencing (WGS) allows for the simultaneous analysis of numerous genes on a single platform, enhancing the role of DNA sequencing in clinical diagnostics. These developments are anticipated to significantly propel market growth over the forecast period.

U.S. Next-generation Sequencing Library Preparation Market Report Segmentation

This report forecasts revenue growth at the country level and provides an analysis of the latest industry trends in each of the sub-segments from 2021 to 2033. For this study, the analyst has segmented the U.S. next-generation sequencing library preparation market report based on sequencing type, product, application, end use, and region:

Sequencing Type Outlook (Revenue, USD Million, 2021 - 2033)

  • Targeted Genome Sequencing
  • Whole Genome Sequencing
  • Whole Exome Sequencing
  • Other Sequencing Types

Product Outlook (Revenue, USD Million, 2021 - 2033)

  • Reagents & Consumables
  • DNA Library Preparation Kits
  • RNA Library Preparation Kits
  • Other Reagents & Consumables
  • Instruments

Application Outlook (Revenue, USD Million, 2021 - 2033)

  • Drug & Biomarker Discovery
  • Disease Diagnostics
  • Cancer Diagnostics
  • Reproductive Health Diagnostics
  • Infectious Disease Diagnostics
  • Other Disease Diagnostic Applications
  • Others

End Use Outlook (Revenue, USD Million, 2021 - 2033)

  • Hospitals and Clinics
  • Academic and Research Institutions
  • Pharmaceutical and Biotechnology Companies
  • Others

Why should you buy this report?

  • Comprehensive Market Analysis: Gain detailed insights into the global market across major regions and segments.
  • Competitive Landscape: Explore the market presence of key players worldwide.
  • Future Trends: Discover the pivotal trends and drivers shaping the future of the global market.
  • Actionable Recommendations: Utilize insights to uncover new revenue streams and guide strategic business decisions.

This report addresses:

  • Market intelligence to enable effective decision-making
  • Market estimates and forecasts from 2018 to 2030
  • Growth opportunities and trend analyses
  • Segment and regional revenue forecasts for market assessment
  • Competition strategy and market share analysis
  • Product innovation listing for you to stay ahead of the curve
  • COVID-19's impact and how to sustain in these fast-evolving markets

This product will be delivered within 2 business days.

Table of Contents

Chapter 1. Methodology and Scope
1.1. Market Segmentation & Scope
1.2. Market Definitions
1.2.1. Sequencing Type Segment
1.2.2. Product Segment
1.2.3. Application Segment
1.2.4. End Use Segment
1.3. Information analysis
1.3.1. Market formulation & data visualization
1.4. Data validation & publishing
1.5. Information Procurement
1.5.1. Primary Research
1.6. Information or Data Analysis
1.7. Market Formulation & Validation
1.8. Market Model
1.9. Total Market: CAGR Calculation
1.10. Objectives
Chapter 2. Executive Summary
2.1. Market Outlook
2.2. Segmental Snapshot
2.3. Competitive Landscape Snapshot
Chapter 3. Market Variables, Trends, and Scope
3.1. Market Lineage
3.1.1. Parent Market Analysis
3.1.2. Ancillary Market Analysis
3.2. U.S. Next-generation Sequencing Library Preparation Market - Market Dynamics
3.2.1. Market Driver Analysis
3.2.2. Market Restraint Analysis
3.3. Market Analysis Tools
3.3.1. Porter’s Five Forces Analysis
3.3.2. SWOT Analysis, By Factor (Political & Legal, Economic And Technological)
3.3.3. COVID-19 Impact Analysis
Chapter 4. U.S. Next-generation Sequencing Library Preparation Market: Sequencing Type Business Analysis
4.1. Sequencing Type Segment Dashboard
4.2. U.S. Next-generation Sequencing Library Preparation Market Sequencing Type Movement Analysis, 2024 & 2033
4.3. U.S. Next-generation Sequencing Library Preparation Market Size & Trend Analysis, by Sequencing Type, 2021 to 2033 (USD Million)
4.4. Targeted Genome Sequencing
4.4.1. Targeted Genome Sequencing Market Estimates And Forecasts, 2021 - 2033 (USD Million)
4.5. Whole Genome Sequencing
4.5.1. Whole Genome Sequencing Market Estimates And Forecasts, 2021 - 2033 (USD Million)
4.6. Whole Exome Sequencing
4.6.1. Whole Exome Sequencing Market Estimates And Forecasts, 2021 - 2033 (USD Million)
4.7. Other Sequencing Types
4.7.1. Other Sequencing Types Market Estimates And Forecasts, 2021 - 2033 (USD Million)
Chapter 5. U.S. Next-generation Sequencing Library Preparation Market: Product Business Analysis
5.1. Product Segment Dashboard
5.2. U.S. Next-generation Sequencing Library Preparation Market Product Movement Analysis, 2024 & 2033
5.3. U.S. Next-generation Sequencing Library Preparation Market Size & Trend Analysis, by Product, 2021 to 2033 (USD Million)
5.4. Reagents & Consumables
5.4.1. Reagents & Consumables Market Estimates And Forecasts, 2021 - 2033 (USD Million)
5.4.2. DNA Library Preparation Kits
5.4.2.1. DNA Library Preparation Kits Market Estimates And Forecasts, 2021 - 2033 (USD Million)
5.4.3. RNA Library Preparation Kits
5.4.3.1. RNA Library Preparation Kits Market Estimates And Forecasts, 2021 - 2033 (USD Million)
5.4.4. Other Reagents & Consumables
5.4.4.1. Other Reagents & Consumables Market Estimates And Forecasts, 2021 - 2033 (USD Million)
5.5. Instruments
5.5.1. Instruments Market Estimates And Forecasts, 2021 - 2033 (USD Million)
Chapter 6. U.S. Next-generation Sequencing Library Preparation Market: Application Business Analysis
6.1. Application Segment Dashboard
6.2. U.S. Next-generation Sequencing Library Preparation Market Application Movement Analysis, 2024 & 2033
6.3. U.S. Next-generation Sequencing Library Preparation Market Size & Trend Analysis, by Application, 2021 to 2033 (USD Million)
6.4. Drug & Biomarker Discovery
6.4.1. Drug & Biomarker Discovery Market Estimates And Forecasts, 2021 - 2033 (USD Million)
6.5. Disease Diagnostics
6.5.1. Disease Diagnostics Market Estimates And Forecasts, 2021 - 2033 (USD Million)
6.5.2. Cancer Diagnostics
6.5.2.1. Cancer Diagnostics Market Estimates And Forecasts, 2021 - 2033 (USD Million)
6.5.3. Reproductive Health Diagnostics
6.5.3.1. Reproductive Health Diagnostics Market Estimates And Forecasts, 2021 - 2033 (USD Million)
6.5.4. Infectious Disease Diagnostics
6.5.4.1. Infectious Disease Diagnostics Market Estimates And Forecasts, 2021 - 2033 (USD Million)
6.5.5. Other Disease Diagnostic Applications
6.5.5.1. Other Disease Diagnostic Applications Market Estimates And Forecasts, 2021 - 2033 (USD Million)
6.6. Others
6.6.1. Others Market Estimates And Forecasts, 2021 - 2033 (USD Million)
Chapter 7. U.S. Next-generation Sequencing Library Preparation Market: End Use Business Analysis
7.1. End Use Segment Dashboard
7.2. U.S. Next-generation Sequencing Library Preparation Market End Use Movement Analysis, 2024 & 2033
7.3. U.S. Next-generation Sequencing Library Preparation Market Size & Trend Analysis, by End Use, 2021 to 2033 (USD Million)
7.4. Hospitals and Clinics
7.4.1. Hospitals and Clinics Market Estimates And Forecasts, 2021 - 2033 (USD Million)
7.5. Academic and Research Institutions
7.5.1. Academic and Research Institutions Market Estimates And Forecasts, 2021 - 2033 (USD Million)
7.6. Pharmaceutical and Biotechnology Companies
7.6.1. Pharmaceutical and Biotechnology Companies Market Estimates And Forecasts, 2021 - 2033 (USD Million)
7.7. Others
7.7.1. Others Market Estimates And Forecasts, 2021 - 2033 (USD Million)
Chapter 8. Competitive Landscape
8.1. Company/Competition Categorization
8.2. Strategy Mapping
8.3. Company Market Position Analysis, 2024
8.4. Company Profiles/Listing
8.4.1. Illumina, Inc.
8.4.1.1. Company overview
8.4.1.2. Financial performance
8.4.1.3. Product benchmarking
8.4.1.4. Strategic initiatives
8.4.2. Agilent Technologies, Inc.
8.4.2.1. Company overview
8.4.2.2. Financial performance
8.4.2.3. Product benchmarking
8.4.2.4. Strategic initiatives
8.4.3. F. Hoffmann-La Roche AG, Inc.
8.4.3.1. Company overview
8.4.3.2. Financial performance
8.4.3.3. Product benchmarking
8.4.3.4. Strategic initiatives
8.4.4. BD
8.4.4.1. Company overview
8.4.4.2. Financial performance
8.4.4.3. Product benchmarking
8.4.4.4. Strategic initiatives
8.4.5. Oxford Nanopore Technologies
8.4.5.1. Company overview
8.4.5.2. Financial performance
8.4.5.3. Product benchmarking
8.4.5.4. Strategic initiatives
8.4.6. New England Biolabs Inc.
8.4.6.1. Company overview
8.4.6.2. Financial performance
8.4.6.3. Product benchmarking
8.4.6.4. Strategic initiatives
8.4.7. Revvity, Inc.
8.4.7.1. Company overview
8.4.7.2. Financial performance
8.4.7.3. Product benchmarking
8.4.7.4. Strategic initiatives
8.4.8. QIAGEN N.V.
8.4.8.1. Company overview
8.4.8.2. Financial performance
8.4.8.3. Product benchmarking
8.4.8.4. Strategic initiatives
8.4.9. Pacific Biosciences of California, Inc.
8.4.9.1. Company overview
8.4.9.2. Financial performance
8.4.9.3. Product benchmarking
8.4.9.4. Strategic initiatives
8.4.10. Thermo Fisher Scientific Inc.
8.4.10.1. Company overview
8.4.10.2. Financial performance
8.4.10.3. Product benchmarking
8.4.10.4. Strategic initiatives
List of Tables
Table 1 List of secondary sources
Table 2 List of abbreviations
Table 3 U.S. next-generation sequencing library preparation market, by product, 2021 - 2033 (USD Million)
Table 4 U.S. next-generation sequencing library preparation market, by sequencing type, 2021 - 2033 (USD Million)
Table 5 U.S. next-generation sequencing library preparation market, by application, 2021 - 2033 (USD Million)
Table 6 U.S. next-generation sequencing library preparation market, by end use, 2021 - 2033 (USD Million)
Table 7 Participant's overview
Table 8 Financial performance
Table 9 Key companies undergoing expansions
Table 10 Key companies undergoing acquisitions
Table 11 Key companies undergoing collaborations
Table 12 Key companies launching new products/services
Table 13 Key companies undergoing partnerships
Table 14 Key companies undertaking other strategies
List of Figures
Fig. 1 U.S. next-generation sequencing library preparation market segmentation
Fig. 2 Data analysis models
Fig. 3 Market formulation and validation
Fig. 4 Data validating & publishing
Fig. 5 Market research process
Fig. 6 Information procurement
Fig. 7 Primary research
Fig. 8 Value-chain-based sizing & forecasting
Fig. 9 QFD modelling for market share assessment
Fig. 10 Market formulation & validation
Fig. 11 Commodity flow analysis
Fig. 12 Market outlook
Fig. 13 Segment snapshot-1
Fig. 14 Segment snapshot-2
Fig. 15 Competitive landscape snapshot
Fig. 16 Market trends & outlook
Fig. 17 Porter’s five force analysis
Fig. 18 PESTEL analysis
Fig. 19 U.S. next-generation sequencing library preparation market: Sequencing type outlook and key takeaways
Fig. 20 U.S. next-generation sequencing library preparation market: Sequencing type market share analysis, 2024 & 2033
Fig. 21 Targeted genome sequencing market, 2021 - 2033 (USD Million)
Fig. 22 Whole genome sequencing market, 2021 - 2033 (USD Million)
Fig. 23 Whole exome sequencing market, 2021 - 2033 (USD Million)
Fig. 24 other sequencing types market, 2021 - 2033 (USD Million)
Fig. 25 U.S. next-generation sequencing library preparation market: Product outlook and key takeaways
Fig. 26 U.S. next-generation sequencing library preparation market: Product market share analysis, 2024 & 2033
Fig. 27 Instruments market, 2021 - 2033 (USD Million)
Fig. 28 Reagents & consumables market, 2021 - 2033 (USD Million)
Fig. 29 RNA library preparation kits market, 2021 - 2033 (USD Million)
Fig. 30 Other reagents & consumables market, 2021 - 2033 (USD Million)
Fig. 31 U.S. next-generation sequencing library preparation market: Application outlook and key takeaways
Fig. 32 U.S. next-generation sequencing library preparation market: Application market share analysis, 2024 & 2033
Fig. 33 Drug & biomarker discovery market, 2021 - 2033 (USD Million)
Fig. 34 Disease diagnostics market, 2021 - 2033 (USD Million)
Fig. 35 Cancer diagnostics market, 2021 - 2033 (USD Million)
Fig. 36 Reproductive health diagnostics market, 2021 - 2033 (USD Million)
Fig. 37 Infectious disease diagnostics market, 2021 - 2033 (USD Million)
Fig. 38 Other disease diagnostics market, 2021 - 2033 (USD Million)
Fig. 39 Other applications market, 2021 - 2033 (USD Million)
Fig. 40 U.S. next-generation sequencing library preparation market: End use outlook and key takeaways
Fig. 41 U.S. next-generation sequencing library preparation market: End use market share analysis, 2024 & 2033
Fig. 42 Academic & research institutes market, 2021 - 2033 (USD Million)
Fig. 43 Hospitals & clinics market, 2021 - 2033 (USD Million)
Fig. 44 Pharmaceutical & biotechnology companies market, 2021 - 2033 (USD Million)
Fig. 45 Others market, 2021 - 2033 (USD Million)
Fig. 46 Key company categorization
Fig. 47 Company market positioning, 2024
Fig. 48 Strategy framework

Companies Mentioned

  • Illumina, Inc.
  • Agilent Technologies, Inc.
  • F. Hoffmann-La Roche AG, Inc.
  • BD
  • Oxford Nanopore Technologies
  • New England Biolabs Inc.
  • Revvity, Inc.
  • QIAGEN N.V.
  • Pacific Biosciences of California, Inc.
  • Thermo Fisher Scientific Inc.

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About the NGS Library Preparation Market

The NGS Library Preparation market is a segment of the biotechnology industry that focuses on the preparation of libraries for Next Generation Sequencing (NGS). This process involves the fragmentation of DNA, the addition of adapters, and the amplification of the fragments. The libraries are then used to sequence the DNA and generate data for downstream analysis. The NGS Library Preparation market is driven by the increasing demand for NGS-based applications in research and clinical settings. This includes applications such as gene expression analysis, genotyping, and metagenomics. The market is also driven by the development of new technologies and products that enable faster and more accurate library preparation. Companies in the NGS Library Preparation market include Illumina, Thermo Fisher Scientific, Agilent Technologies, QIAGEN, and New England Biolabs. Show Less Read more

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