Disease Pathways. An Atlas of Human Disease Signaling Pathways

Table of Contents

1. Part One1. Introduction to the cell signaling biochemistry and proteomics2. System biology and signaling pathways3. Complexity of molecular mechanisms of human diseases

2. Part Two1. Cardiovascular Diseases2. Dermatological Diseases3. Endocrine and Metabolic Diseases4. Intestinal Diseases5. Musculoskeletal System Diseases6. Neurological Diseases7. Obstetrics and Gynecology Diseases8. Ophthalmology/Eye Diseases9. Otolaryngological Diseases10. Respirator and Pulmonology Diseases11. Nephrology Diseases

3. Part Three1. Methods of using intracellular maps for diagnosis of diseases in personalized medicine2. Conclusion

Authors

Anastasia P. Nesterova Senior Scientist, Elsevier Inc., Rockville, MD, USA. Dr. Nesterova is a senior scientist in the Life Science Research and Development Department at Elsevier with a focus on mammalian genetics and human diseases. For five years, her team compiled signaling pathways for over 250 diseases using the Elsevier Pathway StudioT software and database. Anton Yuryev Elsevier Inc., Rockville, MD, USA. Dr. Anton Yuryev works as the Professional Services Director at Elsevier and is responsible for development of targeted bioinformatics solutions using Elsevier software and knowledge bases for areas of drug research, personalized medicine and agrobiology. Eugene A. Klimov Elsevier Inc. / Novel Software Systems, Moscow, Russia. Dr. Eugene A. Klimov is Head of the group of Medical and Veterinary Genetics in the Faculty of Biology and is the lecturer at Lomonosov Moscow State University. Dr. Klimov has 15 years of experience in structural and functional genomics, molecular biology, viral and neurological diseases. Maria Zharkova Scientist, Elsevier Inc. / Novel Software Systems, Moscow, Russia. Dr. Maria Zharkova, Novel Software Systems employee, working as a scientist at the Life Science Research and Development Department at Elsevier with primary research interests in protein biology and biochemistry. Maria Shkrob Elsevier Inc., Rockville, MD, USA. Dr. Maria Shkrob has 7 years of experience in the bioinformatics industry, working on the solutions for text and data mining. At Elsevier, she works as a Consultant for Elsevier Professional Services applying the rich R&D Solutions portfolio to address customers' needs. Natalia V. Ivanikova Scientist, Elsevier Inc. / Novel Software Systems, Saint-Petersburg, Russia. Natalia Ivanikova, PhD, Novel Software Systems employee, works as a senior scientist at the Content and Innovation group at Elsevier's Operations division with a focus on the automated construction of biological knowledge bases using natural language processing technologies. Sergey Sozin Scientist, Elsevier Inc. / Novel Software Systems, Saint-Petersburg, Russia. Sergei Sozin, M.D., Novel Software Systems employee, works as a scientist at the Life Science Research and Development Department at Elsevier with a focus on internal medicine, hematology, cancer biology, oncogenomics, and clinical trials. Vladimir Sobolev Scientist, Elsevier Inc. / Novel Software Systems, Moscow, Russia. Dr. Vladimir Sobolev is a senior scientist at the Mechnikov Research Institute of Vaccines and Sera, and at the Center for Theoretical Problems of Physicochemical Pharmacology, Russian Academy of Science. Dr. Sobolev specializes in cell biology and immunology.